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Body weight was measured every 2-day interval during the treatment. A significant reduction in body weight has been observed after adenine treatment. However, treatment with eitherT3, Baicalein (BAI) and combined (T3 + BAI) showed a significant gain in the body weight of animals. n = 10 per group. **, and *** indicate the significance level at p ≤ 0.01, and p ≤ 0.001, respectively.

Journal: bioRxiv

Article Title: A Dual intervention of Triiodothyronine and Baicalein bi-directionally upregulates Klotho with attenuation of chronic kidney disease and its complications in aged BALB/c mice

doi: 10.1101/2024.09.08.611868

Figure Lengend Snippet: Body weight was measured every 2-day interval during the treatment. A significant reduction in body weight has been observed after adenine treatment. However, treatment with eitherT3, Baicalein (BAI) and combined (T3 + BAI) showed a significant gain in the body weight of animals. n = 10 per group. **, and *** indicate the significance level at p ≤ 0.01, and p ≤ 0.001, respectively.

Article Snippet: Baicalein (BAI) (Sigma Aldrich, USA) were named after their treatment.

Techniques:

Schematic representation of bi-directional treatment using Triiodothyronine and Baicalein to upregulate and stabilize Klotho expression.

Journal: bioRxiv

Article Title: A Dual intervention of Triiodothyronine and Baicalein bi-directionally upregulates Klotho with attenuation of chronic kidney disease and its complications in aged BALB/c mice

doi: 10.1101/2024.09.08.611868

Figure Lengend Snippet: Schematic representation of bi-directional treatment using Triiodothyronine and Baicalein to upregulate and stabilize Klotho expression.

Article Snippet: Baicalein (BAI) (Sigma Aldrich, USA) were named after their treatment.

Techniques: Expressing