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Identifying differences in the deep capillary plexus (DCP) between projection artifact removal (PAROCTA) and non-PAROCTA processed eyes. ( A, B ) Binarized images of the DCP using PAROCTA and non-PAROCTA versions of the software. ( C ) Pixels exclusive to PAROCTA obtained by subtracting the non-PAROCTA image from the PAROCTA image. ( D ) Pixels exclusive to non-PAROCTA obtained by subtracting the PAROCTA image from the non-PAROCTA image. ( E , F ) Pixels unique to each version of the software (green) overlaid on the superficial capillary plexus (SCP) (Red) with common pixels shown in yellow, demonstrating that differences unique to non-PAROCTA are mainly projection artifacts from the SCP while those exclusive from PAROCTA originate from the DCP. ( G ) Pixels unique to PAROCTA (green) when overlaid on the non-PAROCTA DCP (red) demonstrate “recovery” of finer capillaries not previously visualized on non-PAROCTA.

Journal: Translational Vision Science & Technology

Article Title: Optical Coherence Tomography Angiography Projection Artifact Removal: Impact on Capillary Density and Interaction with Diabetic Retinopathy Severity

doi: 10.1167/tvst.9.7.10

Figure Lengend Snippet: Identifying differences in the deep capillary plexus (DCP) between projection artifact removal (PAROCTA) and non-PAROCTA processed eyes. ( A, B ) Binarized images of the DCP using PAROCTA and non-PAROCTA versions of the software. ( C ) Pixels exclusive to PAROCTA obtained by subtracting the non-PAROCTA image from the PAROCTA image. ( D ) Pixels exclusive to non-PAROCTA obtained by subtracting the PAROCTA image from the non-PAROCTA image. ( E , F ) Pixels unique to each version of the software (green) overlaid on the superficial capillary plexus (SCP) (Red) with common pixels shown in yellow, demonstrating that differences unique to non-PAROCTA are mainly projection artifacts from the SCP while those exclusive from PAROCTA originate from the DCP. ( G ) Pixels unique to PAROCTA (green) when overlaid on the non-PAROCTA DCP (red) demonstrate “recovery” of finer capillaries not previously visualized on non-PAROCTA.

Article Snippet: Several strategies have been implemented to reduce the effects of projection artifacts, which range from slab removal to projection resolved OCTA (PR-OCTA)., Recently, Garrity et al. described the use of a novel 3-D projection artifact removal software (PAROCTA) currently available as part of the AngioVue software (RTvue XR Avanti; Optovue, Fremont, CA).

Techniques: Software

Comparison Between Manual non-PAROCTA and PAROCTA VD Measurements Across DR Severity

Journal: Translational Vision Science & Technology

Article Title: Optical Coherence Tomography Angiography Projection Artifact Removal: Impact on Capillary Density and Interaction with Diabetic Retinopathy Severity

doi: 10.1167/tvst.9.7.10

Figure Lengend Snippet: Comparison Between Manual non-PAROCTA and PAROCTA VD Measurements Across DR Severity

Article Snippet: Several strategies have been implemented to reduce the effects of projection artifacts, which range from slab removal to projection resolved OCTA (PR-OCTA)., Recently, Garrity et al. described the use of a novel 3-D projection artifact removal software (PAROCTA) currently available as part of the AngioVue software (RTvue XR Avanti; Optovue, Fremont, CA).

Techniques: Comparison

Differences between PAROCTA and non-PAROCTA vessel density measurements in superficial (SCP) and deep capillary plexus (DCP) across different DR severity levels.

Journal: Translational Vision Science & Technology

Article Title: Optical Coherence Tomography Angiography Projection Artifact Removal: Impact on Capillary Density and Interaction with Diabetic Retinopathy Severity

doi: 10.1167/tvst.9.7.10

Figure Lengend Snippet: Differences between PAROCTA and non-PAROCTA vessel density measurements in superficial (SCP) and deep capillary plexus (DCP) across different DR severity levels.

Article Snippet: Several strategies have been implemented to reduce the effects of projection artifacts, which range from slab removal to projection resolved OCTA (PR-OCTA)., Recently, Garrity et al. described the use of a novel 3-D projection artifact removal software (PAROCTA) currently available as part of the AngioVue software (RTvue XR Avanti; Optovue, Fremont, CA).

Techniques:

Bar graphs demonstrating the differences between PAROCTA and non-PAROCTA in different diabetic retinopathy (DR) severity levels. The upper row illustrates changes in the SCP demonstrating that with increasing DR severity levels vessel density (VD) and vessel length density (VLD) decreases in both versions of the software. PAROCTA measurements are lower for both the VD and VLD, with increasing disparity with higher DR severity levels. The lower row illustrates changes in the DCP demonstrating similar trends to the SCP. However, PAROCTA measurements are greater for both the VD and VLD, with greater disparity in milder DR.

Journal: Translational Vision Science & Technology

Article Title: Optical Coherence Tomography Angiography Projection Artifact Removal: Impact on Capillary Density and Interaction with Diabetic Retinopathy Severity

doi: 10.1167/tvst.9.7.10

Figure Lengend Snippet: Bar graphs demonstrating the differences between PAROCTA and non-PAROCTA in different diabetic retinopathy (DR) severity levels. The upper row illustrates changes in the SCP demonstrating that with increasing DR severity levels vessel density (VD) and vessel length density (VLD) decreases in both versions of the software. PAROCTA measurements are lower for both the VD and VLD, with increasing disparity with higher DR severity levels. The lower row illustrates changes in the DCP demonstrating similar trends to the SCP. However, PAROCTA measurements are greater for both the VD and VLD, with greater disparity in milder DR.

Article Snippet: Several strategies have been implemented to reduce the effects of projection artifacts, which range from slab removal to projection resolved OCTA (PR-OCTA)., Recently, Garrity et al. described the use of a novel 3-D projection artifact removal software (PAROCTA) currently available as part of the AngioVue software (RTvue XR Avanti; Optovue, Fremont, CA).

Techniques: Software

( A ) Figure illustrating differences in the superficial capillary plexus (SCP) and deep capillary plexus (DCP) between projection artifact removal optical coherence tomography angiography (PAROCTA) and non-PAROCTA in an eye with no DR. The SCP appears to have similar vessel density in both PAR and non-PAROCTA images. The DCP using non-PAROCTA has many projection artifacts ( blue arrowheads ) and appears less dense compared to the PAROCTA image. ( B ) Image showing the difference between projection artifact removal optical coherence tomography angiography (PAROCTA) and non-PAROCTA in an eye with proliferative diabetic retinopathy (PDR) showing decreased vessel density (VD) in the superficial capillary plexus (SCP) with similar VD in the deep capillary plexus (DCP). Due to a decrease in SCP VD, fewer projection artifacts ( blue arrowheads ) are visible in the DCP in this eye with PDR compared to the eye with no DR.

Journal: Translational Vision Science & Technology

Article Title: Optical Coherence Tomography Angiography Projection Artifact Removal: Impact on Capillary Density and Interaction with Diabetic Retinopathy Severity

doi: 10.1167/tvst.9.7.10

Figure Lengend Snippet: ( A ) Figure illustrating differences in the superficial capillary plexus (SCP) and deep capillary plexus (DCP) between projection artifact removal optical coherence tomography angiography (PAROCTA) and non-PAROCTA in an eye with no DR. The SCP appears to have similar vessel density in both PAR and non-PAROCTA images. The DCP using non-PAROCTA has many projection artifacts ( blue arrowheads ) and appears less dense compared to the PAROCTA image. ( B ) Image showing the difference between projection artifact removal optical coherence tomography angiography (PAROCTA) and non-PAROCTA in an eye with proliferative diabetic retinopathy (PDR) showing decreased vessel density (VD) in the superficial capillary plexus (SCP) with similar VD in the deep capillary plexus (DCP). Due to a decrease in SCP VD, fewer projection artifacts ( blue arrowheads ) are visible in the DCP in this eye with PDR compared to the eye with no DR.

Article Snippet: Several strategies have been implemented to reduce the effects of projection artifacts, which range from slab removal to projection resolved OCTA (PR-OCTA)., Recently, Garrity et al. described the use of a novel 3-D projection artifact removal software (PAROCTA) currently available as part of the AngioVue software (RTvue XR Avanti; Optovue, Fremont, CA).

Techniques: Tomography

Comparison Between PAROCTA and non-PAROCTA Vessel Density, Vessel Linear Density and Adjusted Flow Index in Full Thickness OCTA Slabs

Journal: Translational Vision Science & Technology

Article Title: Optical Coherence Tomography Angiography Projection Artifact Removal: Impact on Capillary Density and Interaction with Diabetic Retinopathy Severity

doi: 10.1167/tvst.9.7.10

Figure Lengend Snippet: Comparison Between PAROCTA and non-PAROCTA Vessel Density, Vessel Linear Density and Adjusted Flow Index in Full Thickness OCTA Slabs

Article Snippet: Several strategies have been implemented to reduce the effects of projection artifacts, which range from slab removal to projection resolved OCTA (PR-OCTA)., Recently, Garrity et al. described the use of a novel 3-D projection artifact removal software (PAROCTA) currently available as part of the AngioVue software (RTvue XR Avanti; Optovue, Fremont, CA).

Techniques: Comparison

Image demonstrating that pixels unique to projection artifact removal optical coherence tomography angiography (PAROCTA) (green) overlaid on the superficial capillary plexus (SCP) (red) for orientation, demonstrating that there are significantly greater differences in eyes with no diabetic retinopathy (DR) (left hand image) compared to eyes with proliferative diabetic retinopathy (PDR) (right hand image).

Journal: Translational Vision Science & Technology

Article Title: Optical Coherence Tomography Angiography Projection Artifact Removal: Impact on Capillary Density and Interaction with Diabetic Retinopathy Severity

doi: 10.1167/tvst.9.7.10

Figure Lengend Snippet: Image demonstrating that pixels unique to projection artifact removal optical coherence tomography angiography (PAROCTA) (green) overlaid on the superficial capillary plexus (SCP) (red) for orientation, demonstrating that there are significantly greater differences in eyes with no diabetic retinopathy (DR) (left hand image) compared to eyes with proliferative diabetic retinopathy (PDR) (right hand image).

Article Snippet: Several strategies have been implemented to reduce the effects of projection artifacts, which range from slab removal to projection resolved OCTA (PR-OCTA)., Recently, Garrity et al. described the use of a novel 3-D projection artifact removal software (PAROCTA) currently available as part of the AngioVue software (RTvue XR Avanti; Optovue, Fremont, CA).

Techniques: Tomography