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ova  (MedChemExpress)
94
MedChemExpress ova
Inhibition of the ACC Glu ‐AIC Glu pathway fails to alleviate visceral hypersensitivity in a non‐mental stress model. (A,B) VMR to 40 and 60mmHg CRD stimulation. <t>OVA:</t> ovalbumin. Representative external abdominal oblique muscle EMG recordings in (A), analysis of the mean amplitude of △EMG in (B) (one‐way ANOVA test followed by Tukey's post‐hoc test, B, 40mmHg, F (2, 17) = 67.67, p < 0.0001; Kruskal–Wallis test followed by Dunnett's post‐hoc test, B, 60mmHg, p = 0.0003. (C) Schematic of bilateral rAAV virus injections in ACC of OVA rats. (D) Representative image of <t>ACC</t> <t>injection</t> sites. Scale bar, 200 µm. (E,F) C‐fos expression in ACC post‐virus injection. Representative images of colocalization in (E), statistical results in (F), Scale bar, 20 µm (unpaired Student's t ‐test, F, t (10) = 8.202, p < 0.0001). (G–J) Inhibition of ACC Glu relieves the visceral hypersensitivity induced by OVA. Representative external abdominal oblique muscle EMG recordings in (G), analysis of the mean amplitude of △EMG in (H–J) (Paired Student's t ‐test, H, 40mmHg, t (5) = 2.347, p = 0.0658; 60mmHg, t (5) = 0.2801, p = 0.7906; I, 40mmHg, t (5) = 4.486, p = 0.0065; 60mmHg, t (5) = 3.139, p = 0.0257; Unpaired Student's t ‐test, J, 40mmHg, t (10) = 7.46, p < 0.0001; 60mmHg, t (10) = 4.313, p = 0.0015. (K) Schematic of bilateral anterograde‐DIO (in ACC) and retrograde‐CRE (in AIC) virus injections in OVA rats. (L) Representative image of ACC injection sites. Scale bar, 200 µm. (M,N) C‐fos expression in ACC post‐virus injection. Representative images of colocalization in (M), statistical results in (N), Scale bar, 20 µm (unpaired Student's t ‐test, N, t (10) = 0.1144, p = 0.9112). (O‐R) Failure of ACC‐AIC circuit inhibition to reduce OVA‐induced visceral hypersensitivity. Representative external abdominal oblique muscle EMG recordings in (O), analysis of the mean amplitude of △EMG in (P‐R) (paired Student's t ‐test, P, 40mmHg, t (5) = 0.4976, p = 0.6399; 60mmHg, t (5) = 0.2252, p = 0.8308; Q, 40mmHg, t (5) = 0.9588, p = 0.3817; 60mmHg, t (5) = 0.7854, p = 0.4678; unpaired Student's t ‐test, R, 40mmHg, t (10) = 0.5248, p = 0.6111; 60mmHg, t (10) = 0.1117, p = 0.9132). Data presented as mean ± SEM ( n = 8 rats for the NC group and n = 6 rats for all other groups). * p < 0.05, ** p < 0.01, *** p < 0.001, **** p < 0.0001.
Ova, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/aluminum+hydroxide/Aluminum+Hydroxide/pmc13418048-245-13-15
Average 94 stars, based on 1 article reviews
ova - by Bioz Stars, 2026-11
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aluminum hydroxide  (InvivoGen)
99
InvivoGen aluminum hydroxide
Inhibition of the ACC Glu ‐AIC Glu pathway fails to alleviate visceral hypersensitivity in a non‐mental stress model. (A,B) VMR to 40 and 60mmHg CRD stimulation. <t>OVA:</t> ovalbumin. Representative external abdominal oblique muscle EMG recordings in (A), analysis of the mean amplitude of △EMG in (B) (one‐way ANOVA test followed by Tukey's post‐hoc test, B, 40mmHg, F (2, 17) = 67.67, p < 0.0001; Kruskal–Wallis test followed by Dunnett's post‐hoc test, B, 60mmHg, p = 0.0003. (C) Schematic of bilateral rAAV virus injections in ACC of OVA rats. (D) Representative image of <t>ACC</t> <t>injection</t> sites. Scale bar, 200 µm. (E,F) C‐fos expression in ACC post‐virus injection. Representative images of colocalization in (E), statistical results in (F), Scale bar, 20 µm (unpaired Student's t ‐test, F, t (10) = 8.202, p < 0.0001). (G–J) Inhibition of ACC Glu relieves the visceral hypersensitivity induced by OVA. Representative external abdominal oblique muscle EMG recordings in (G), analysis of the mean amplitude of △EMG in (H–J) (Paired Student's t ‐test, H, 40mmHg, t (5) = 2.347, p = 0.0658; 60mmHg, t (5) = 0.2801, p = 0.7906; I, 40mmHg, t (5) = 4.486, p = 0.0065; 60mmHg, t (5) = 3.139, p = 0.0257; Unpaired Student's t ‐test, J, 40mmHg, t (10) = 7.46, p < 0.0001; 60mmHg, t (10) = 4.313, p = 0.0015. (K) Schematic of bilateral anterograde‐DIO (in ACC) and retrograde‐CRE (in AIC) virus injections in OVA rats. (L) Representative image of ACC injection sites. Scale bar, 200 µm. (M,N) C‐fos expression in ACC post‐virus injection. Representative images of colocalization in (M), statistical results in (N), Scale bar, 20 µm (unpaired Student's t ‐test, N, t (10) = 0.1144, p = 0.9112). (O‐R) Failure of ACC‐AIC circuit inhibition to reduce OVA‐induced visceral hypersensitivity. Representative external abdominal oblique muscle EMG recordings in (O), analysis of the mean amplitude of △EMG in (P‐R) (paired Student's t ‐test, P, 40mmHg, t (5) = 0.4976, p = 0.6399; 60mmHg, t (5) = 0.2252, p = 0.8308; Q, 40mmHg, t (5) = 0.9588, p = 0.3817; 60mmHg, t (5) = 0.7854, p = 0.4678; unpaired Student's t ‐test, R, 40mmHg, t (10) = 0.5248, p = 0.6111; 60mmHg, t (10) = 0.1117, p = 0.9132). Data presented as mean ± SEM ( n = 8 rats for the NC group and n = 6 rats for all other groups). * p < 0.05, ** p < 0.01, *** p < 0.001, **** p < 0.0001.
Aluminum Hydroxide, supplied by InvivoGen, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/aluminum+hydroxide/Alhydrogel+adjuvant+2%25/pmc13524200-45-0-5
Average 99 stars, based on 1 article reviews
aluminum hydroxide - by Bioz Stars, 2026-11
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rea cws alum  (MedChemExpress)
94
MedChemExpress rea cws alum
Inhibition of the ACC Glu ‐AIC Glu pathway fails to alleviate visceral hypersensitivity in a non‐mental stress model. (A,B) VMR to 40 and 60mmHg CRD stimulation. <t>OVA:</t> ovalbumin. Representative external abdominal oblique muscle EMG recordings in (A), analysis of the mean amplitude of △EMG in (B) (one‐way ANOVA test followed by Tukey's post‐hoc test, B, 40mmHg, F (2, 17) = 67.67, p < 0.0001; Kruskal–Wallis test followed by Dunnett's post‐hoc test, B, 60mmHg, p = 0.0003. (C) Schematic of bilateral rAAV virus injections in ACC of OVA rats. (D) Representative image of <t>ACC</t> <t>injection</t> sites. Scale bar, 200 µm. (E,F) C‐fos expression in ACC post‐virus injection. Representative images of colocalization in (E), statistical results in (F), Scale bar, 20 µm (unpaired Student's t ‐test, F, t (10) = 8.202, p < 0.0001). (G–J) Inhibition of ACC Glu relieves the visceral hypersensitivity induced by OVA. Representative external abdominal oblique muscle EMG recordings in (G), analysis of the mean amplitude of △EMG in (H–J) (Paired Student's t ‐test, H, 40mmHg, t (5) = 2.347, p = 0.0658; 60mmHg, t (5) = 0.2801, p = 0.7906; I, 40mmHg, t (5) = 4.486, p = 0.0065; 60mmHg, t (5) = 3.139, p = 0.0257; Unpaired Student's t ‐test, J, 40mmHg, t (10) = 7.46, p < 0.0001; 60mmHg, t (10) = 4.313, p = 0.0015. (K) Schematic of bilateral anterograde‐DIO (in ACC) and retrograde‐CRE (in AIC) virus injections in OVA rats. (L) Representative image of ACC injection sites. Scale bar, 200 µm. (M,N) C‐fos expression in ACC post‐virus injection. Representative images of colocalization in (M), statistical results in (N), Scale bar, 20 µm (unpaired Student's t ‐test, N, t (10) = 0.1144, p = 0.9112). (O‐R) Failure of ACC‐AIC circuit inhibition to reduce OVA‐induced visceral hypersensitivity. Representative external abdominal oblique muscle EMG recordings in (O), analysis of the mean amplitude of △EMG in (P‐R) (paired Student's t ‐test, P, 40mmHg, t (5) = 0.4976, p = 0.6399; 60mmHg, t (5) = 0.2252, p = 0.8308; Q, 40mmHg, t (5) = 0.9588, p = 0.3817; 60mmHg, t (5) = 0.7854, p = 0.4678; unpaired Student's t ‐test, R, 40mmHg, t (10) = 0.5248, p = 0.6111; 60mmHg, t (10) = 0.1117, p = 0.9132). Data presented as mean ± SEM ( n = 8 rats for the NC group and n = 6 rats for all other groups). * p < 0.05, ** p < 0.01, *** p < 0.001, **** p < 0.0001.
Rea Cws Alum, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/aluminum+hydroxide/Aluminum+Hydroxide/pm42048730-88-14-13
Average 94 stars, based on 1 article reviews
rea cws alum - by Bioz Stars, 2026-11
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aluminum hydroxide al oh 3 gel  (InvivoGen)
99
InvivoGen aluminum hydroxide al oh 3 gel
Inhibition of the ACC Glu ‐AIC Glu pathway fails to alleviate visceral hypersensitivity in a non‐mental stress model. (A,B) VMR to 40 and 60mmHg CRD stimulation. <t>OVA:</t> ovalbumin. Representative external abdominal oblique muscle EMG recordings in (A), analysis of the mean amplitude of △EMG in (B) (one‐way ANOVA test followed by Tukey's post‐hoc test, B, 40mmHg, F (2, 17) = 67.67, p < 0.0001; Kruskal–Wallis test followed by Dunnett's post‐hoc test, B, 60mmHg, p = 0.0003. (C) Schematic of bilateral rAAV virus injections in ACC of OVA rats. (D) Representative image of <t>ACC</t> <t>injection</t> sites. Scale bar, 200 µm. (E,F) C‐fos expression in ACC post‐virus injection. Representative images of colocalization in (E), statistical results in (F), Scale bar, 20 µm (unpaired Student's t ‐test, F, t (10) = 8.202, p < 0.0001). (G–J) Inhibition of ACC Glu relieves the visceral hypersensitivity induced by OVA. Representative external abdominal oblique muscle EMG recordings in (G), analysis of the mean amplitude of △EMG in (H–J) (Paired Student's t ‐test, H, 40mmHg, t (5) = 2.347, p = 0.0658; 60mmHg, t (5) = 0.2801, p = 0.7906; I, 40mmHg, t (5) = 4.486, p = 0.0065; 60mmHg, t (5) = 3.139, p = 0.0257; Unpaired Student's t ‐test, J, 40mmHg, t (10) = 7.46, p < 0.0001; 60mmHg, t (10) = 4.313, p = 0.0015. (K) Schematic of bilateral anterograde‐DIO (in ACC) and retrograde‐CRE (in AIC) virus injections in OVA rats. (L) Representative image of ACC injection sites. Scale bar, 200 µm. (M,N) C‐fos expression in ACC post‐virus injection. Representative images of colocalization in (M), statistical results in (N), Scale bar, 20 µm (unpaired Student's t ‐test, N, t (10) = 0.1144, p = 0.9112). (O‐R) Failure of ACC‐AIC circuit inhibition to reduce OVA‐induced visceral hypersensitivity. Representative external abdominal oblique muscle EMG recordings in (O), analysis of the mean amplitude of △EMG in (P‐R) (paired Student's t ‐test, P, 40mmHg, t (5) = 0.4976, p = 0.6399; 60mmHg, t (5) = 0.2252, p = 0.8308; Q, 40mmHg, t (5) = 0.9588, p = 0.3817; 60mmHg, t (5) = 0.7854, p = 0.4678; unpaired Student's t ‐test, R, 40mmHg, t (10) = 0.5248, p = 0.6111; 60mmHg, t (10) = 0.1117, p = 0.9132). Data presented as mean ± SEM ( n = 8 rats for the NC group and n = 6 rats for all other groups). * p < 0.05, ** p < 0.01, *** p < 0.001, **** p < 0.0001.
Aluminum Hydroxide Al Oh 3 Gel, supplied by InvivoGen, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/aluminum+hydroxide/Alum+Hydroxide/pm42399893-81-0-8
Average 99 stars, based on 1 article reviews
aluminum hydroxide al oh 3 gel - by Bioz Stars, 2026-11
99/100 stars
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aluminum hydroxide gel  (InvivoGen)
99
InvivoGen aluminum hydroxide gel
Inhibition of the ACC Glu ‐AIC Glu pathway fails to alleviate visceral hypersensitivity in a non‐mental stress model. (A,B) VMR to 40 and 60mmHg CRD stimulation. <t>OVA:</t> ovalbumin. Representative external abdominal oblique muscle EMG recordings in (A), analysis of the mean amplitude of △EMG in (B) (one‐way ANOVA test followed by Tukey's post‐hoc test, B, 40mmHg, F (2, 17) = 67.67, p < 0.0001; Kruskal–Wallis test followed by Dunnett's post‐hoc test, B, 60mmHg, p = 0.0003. (C) Schematic of bilateral rAAV virus injections in ACC of OVA rats. (D) Representative image of <t>ACC</t> <t>injection</t> sites. Scale bar, 200 µm. (E,F) C‐fos expression in ACC post‐virus injection. Representative images of colocalization in (E), statistical results in (F), Scale bar, 20 µm (unpaired Student's t ‐test, F, t (10) = 8.202, p < 0.0001). (G–J) Inhibition of ACC Glu relieves the visceral hypersensitivity induced by OVA. Representative external abdominal oblique muscle EMG recordings in (G), analysis of the mean amplitude of △EMG in (H–J) (Paired Student's t ‐test, H, 40mmHg, t (5) = 2.347, p = 0.0658; 60mmHg, t (5) = 0.2801, p = 0.7906; I, 40mmHg, t (5) = 4.486, p = 0.0065; 60mmHg, t (5) = 3.139, p = 0.0257; Unpaired Student's t ‐test, J, 40mmHg, t (10) = 7.46, p < 0.0001; 60mmHg, t (10) = 4.313, p = 0.0015. (K) Schematic of bilateral anterograde‐DIO (in ACC) and retrograde‐CRE (in AIC) virus injections in OVA rats. (L) Representative image of ACC injection sites. Scale bar, 200 µm. (M,N) C‐fos expression in ACC post‐virus injection. Representative images of colocalization in (M), statistical results in (N), Scale bar, 20 µm (unpaired Student's t ‐test, N, t (10) = 0.1144, p = 0.9112). (O‐R) Failure of ACC‐AIC circuit inhibition to reduce OVA‐induced visceral hypersensitivity. Representative external abdominal oblique muscle EMG recordings in (O), analysis of the mean amplitude of △EMG in (P‐R) (paired Student's t ‐test, P, 40mmHg, t (5) = 0.4976, p = 0.6399; 60mmHg, t (5) = 0.2252, p = 0.8308; Q, 40mmHg, t (5) = 0.9588, p = 0.3817; 60mmHg, t (5) = 0.7854, p = 0.4678; unpaired Student's t ‐test, R, 40mmHg, t (10) = 0.5248, p = 0.6111; 60mmHg, t (10) = 0.1117, p = 0.9132). Data presented as mean ± SEM ( n = 8 rats for the NC group and n = 6 rats for all other groups). * p < 0.05, ** p < 0.01, *** p < 0.001, **** p < 0.0001.
Aluminum Hydroxide Gel, supplied by InvivoGen, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/aluminum+hydroxide/Alhydrogel+adjuvant+2%25/pm42346145-58-27-31
Average 99 stars, based on 1 article reviews
aluminum hydroxide gel - by Bioz Stars, 2026-11
99/100 stars
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aluminum hydroxide gel alum adjuvant  (InvivoGen)
99
InvivoGen aluminum hydroxide gel alum adjuvant
Inhibition of the ACC Glu ‐AIC Glu pathway fails to alleviate visceral hypersensitivity in a non‐mental stress model. (A,B) VMR to 40 and 60mmHg CRD stimulation. <t>OVA:</t> ovalbumin. Representative external abdominal oblique muscle EMG recordings in (A), analysis of the mean amplitude of △EMG in (B) (one‐way ANOVA test followed by Tukey's post‐hoc test, B, 40mmHg, F (2, 17) = 67.67, p < 0.0001; Kruskal–Wallis test followed by Dunnett's post‐hoc test, B, 60mmHg, p = 0.0003. (C) Schematic of bilateral rAAV virus injections in ACC of OVA rats. (D) Representative image of <t>ACC</t> <t>injection</t> sites. Scale bar, 200 µm. (E,F) C‐fos expression in ACC post‐virus injection. Representative images of colocalization in (E), statistical results in (F), Scale bar, 20 µm (unpaired Student's t ‐test, F, t (10) = 8.202, p < 0.0001). (G–J) Inhibition of ACC Glu relieves the visceral hypersensitivity induced by OVA. Representative external abdominal oblique muscle EMG recordings in (G), analysis of the mean amplitude of △EMG in (H–J) (Paired Student's t ‐test, H, 40mmHg, t (5) = 2.347, p = 0.0658; 60mmHg, t (5) = 0.2801, p = 0.7906; I, 40mmHg, t (5) = 4.486, p = 0.0065; 60mmHg, t (5) = 3.139, p = 0.0257; Unpaired Student's t ‐test, J, 40mmHg, t (10) = 7.46, p < 0.0001; 60mmHg, t (10) = 4.313, p = 0.0015. (K) Schematic of bilateral anterograde‐DIO (in ACC) and retrograde‐CRE (in AIC) virus injections in OVA rats. (L) Representative image of ACC injection sites. Scale bar, 200 µm. (M,N) C‐fos expression in ACC post‐virus injection. Representative images of colocalization in (M), statistical results in (N), Scale bar, 20 µm (unpaired Student's t ‐test, N, t (10) = 0.1144, p = 0.9112). (O‐R) Failure of ACC‐AIC circuit inhibition to reduce OVA‐induced visceral hypersensitivity. Representative external abdominal oblique muscle EMG recordings in (O), analysis of the mean amplitude of △EMG in (P‐R) (paired Student's t ‐test, P, 40mmHg, t (5) = 0.4976, p = 0.6399; 60mmHg, t (5) = 0.2252, p = 0.8308; Q, 40mmHg, t (5) = 0.9588, p = 0.3817; 60mmHg, t (5) = 0.7854, p = 0.4678; unpaired Student's t ‐test, R, 40mmHg, t (10) = 0.5248, p = 0.6111; 60mmHg, t (10) = 0.1117, p = 0.9132). Data presented as mean ± SEM ( n = 8 rats for the NC group and n = 6 rats for all other groups). * p < 0.05, ** p < 0.01, *** p < 0.001, **** p < 0.0001.
Aluminum Hydroxide Gel Alum Adjuvant, supplied by InvivoGen, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/aluminum+hydroxide/Alhydrogel+adjuvant+2%25/pm42333701-74-9-16
Average 99 stars, based on 1 article reviews
aluminum hydroxide gel alum adjuvant - by Bioz Stars, 2026-11
99/100 stars
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aluminum hydroxide  (Brenntag Inc)
86
Brenntag Inc aluminum hydroxide
Inhibition of the ACC Glu ‐AIC Glu pathway fails to alleviate visceral hypersensitivity in a non‐mental stress model. (A,B) VMR to 40 and 60mmHg CRD stimulation. <t>OVA:</t> ovalbumin. Representative external abdominal oblique muscle EMG recordings in (A), analysis of the mean amplitude of △EMG in (B) (one‐way ANOVA test followed by Tukey's post‐hoc test, B, 40mmHg, F (2, 17) = 67.67, p < 0.0001; Kruskal–Wallis test followed by Dunnett's post‐hoc test, B, 60mmHg, p = 0.0003. (C) Schematic of bilateral rAAV virus injections in ACC of OVA rats. (D) Representative image of <t>ACC</t> <t>injection</t> sites. Scale bar, 200 µm. (E,F) C‐fos expression in ACC post‐virus injection. Representative images of colocalization in (E), statistical results in (F), Scale bar, 20 µm (unpaired Student's t ‐test, F, t (10) = 8.202, p < 0.0001). (G–J) Inhibition of ACC Glu relieves the visceral hypersensitivity induced by OVA. Representative external abdominal oblique muscle EMG recordings in (G), analysis of the mean amplitude of △EMG in (H–J) (Paired Student's t ‐test, H, 40mmHg, t (5) = 2.347, p = 0.0658; 60mmHg, t (5) = 0.2801, p = 0.7906; I, 40mmHg, t (5) = 4.486, p = 0.0065; 60mmHg, t (5) = 3.139, p = 0.0257; Unpaired Student's t ‐test, J, 40mmHg, t (10) = 7.46, p < 0.0001; 60mmHg, t (10) = 4.313, p = 0.0015. (K) Schematic of bilateral anterograde‐DIO (in ACC) and retrograde‐CRE (in AIC) virus injections in OVA rats. (L) Representative image of ACC injection sites. Scale bar, 200 µm. (M,N) C‐fos expression in ACC post‐virus injection. Representative images of colocalization in (M), statistical results in (N), Scale bar, 20 µm (unpaired Student's t ‐test, N, t (10) = 0.1144, p = 0.9112). (O‐R) Failure of ACC‐AIC circuit inhibition to reduce OVA‐induced visceral hypersensitivity. Representative external abdominal oblique muscle EMG recordings in (O), analysis of the mean amplitude of △EMG in (P‐R) (paired Student's t ‐test, P, 40mmHg, t (5) = 0.4976, p = 0.6399; 60mmHg, t (5) = 0.2252, p = 0.8308; Q, 40mmHg, t (5) = 0.9588, p = 0.3817; 60mmHg, t (5) = 0.7854, p = 0.4678; unpaired Student's t ‐test, R, 40mmHg, t (10) = 0.5248, p = 0.6111; 60mmHg, t (10) = 0.1117, p = 0.9132). Data presented as mean ± SEM ( n = 8 rats for the NC group and n = 6 rats for all other groups). * p < 0.05, ** p < 0.01, *** p < 0.001, **** p < 0.0001.
Aluminum Hydroxide, supplied by Brenntag Inc, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/aluminum+hydroxide/aluminum+gel+hydroxide/us12653875-409-3-8
Average 86 stars, based on 1 article reviews
aluminum hydroxide - by Bioz Stars, 2026-11
86/100 stars
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aluminum hydroxide  (Macklin Inc)
86
Macklin Inc aluminum hydroxide
Inhibition of the ACC Glu ‐AIC Glu pathway fails to alleviate visceral hypersensitivity in a non‐mental stress model. (A,B) VMR to 40 and 60mmHg CRD stimulation. <t>OVA:</t> ovalbumin. Representative external abdominal oblique muscle EMG recordings in (A), analysis of the mean amplitude of △EMG in (B) (one‐way ANOVA test followed by Tukey's post‐hoc test, B, 40mmHg, F (2, 17) = 67.67, p < 0.0001; Kruskal–Wallis test followed by Dunnett's post‐hoc test, B, 60mmHg, p = 0.0003. (C) Schematic of bilateral rAAV virus injections in ACC of OVA rats. (D) Representative image of <t>ACC</t> <t>injection</t> sites. Scale bar, 200 µm. (E,F) C‐fos expression in ACC post‐virus injection. Representative images of colocalization in (E), statistical results in (F), Scale bar, 20 µm (unpaired Student's t ‐test, F, t (10) = 8.202, p < 0.0001). (G–J) Inhibition of ACC Glu relieves the visceral hypersensitivity induced by OVA. Representative external abdominal oblique muscle EMG recordings in (G), analysis of the mean amplitude of △EMG in (H–J) (Paired Student's t ‐test, H, 40mmHg, t (5) = 2.347, p = 0.0658; 60mmHg, t (5) = 0.2801, p = 0.7906; I, 40mmHg, t (5) = 4.486, p = 0.0065; 60mmHg, t (5) = 3.139, p = 0.0257; Unpaired Student's t ‐test, J, 40mmHg, t (10) = 7.46, p < 0.0001; 60mmHg, t (10) = 4.313, p = 0.0015. (K) Schematic of bilateral anterograde‐DIO (in ACC) and retrograde‐CRE (in AIC) virus injections in OVA rats. (L) Representative image of ACC injection sites. Scale bar, 200 µm. (M,N) C‐fos expression in ACC post‐virus injection. Representative images of colocalization in (M), statistical results in (N), Scale bar, 20 µm (unpaired Student's t ‐test, N, t (10) = 0.1144, p = 0.9112). (O‐R) Failure of ACC‐AIC circuit inhibition to reduce OVA‐induced visceral hypersensitivity. Representative external abdominal oblique muscle EMG recordings in (O), analysis of the mean amplitude of △EMG in (P‐R) (paired Student's t ‐test, P, 40mmHg, t (5) = 0.4976, p = 0.6399; 60mmHg, t (5) = 0.2252, p = 0.8308; Q, 40mmHg, t (5) = 0.9588, p = 0.3817; 60mmHg, t (5) = 0.7854, p = 0.4678; unpaired Student's t ‐test, R, 40mmHg, t (10) = 0.5248, p = 0.6111; 60mmHg, t (10) = 0.1117, p = 0.9132). Data presented as mean ± SEM ( n = 8 rats for the NC group and n = 6 rats for all other groups). * p < 0.05, ** p < 0.01, *** p < 0.001, **** p < 0.0001.
Aluminum Hydroxide, supplied by Macklin Inc, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/aluminum+hydroxide/aluminum+hydroxide/pm42276317-82-39-41
Average 86 stars, based on 1 article reviews
aluminum hydroxide - by Bioz Stars, 2026-11
86/100 stars
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Inhibition of the ACC Glu ‐AIC Glu pathway fails to alleviate visceral hypersensitivity in a non‐mental stress model. (A,B) VMR to 40 and 60mmHg CRD stimulation. OVA: ovalbumin. Representative external abdominal oblique muscle EMG recordings in (A), analysis of the mean amplitude of △EMG in (B) (one‐way ANOVA test followed by Tukey's post‐hoc test, B, 40mmHg, F (2, 17) = 67.67, p < 0.0001; Kruskal–Wallis test followed by Dunnett's post‐hoc test, B, 60mmHg, p = 0.0003. (C) Schematic of bilateral rAAV virus injections in ACC of OVA rats. (D) Representative image of ACC injection sites. Scale bar, 200 µm. (E,F) C‐fos expression in ACC post‐virus injection. Representative images of colocalization in (E), statistical results in (F), Scale bar, 20 µm (unpaired Student's t ‐test, F, t (10) = 8.202, p < 0.0001). (G–J) Inhibition of ACC Glu relieves the visceral hypersensitivity induced by OVA. Representative external abdominal oblique muscle EMG recordings in (G), analysis of the mean amplitude of △EMG in (H–J) (Paired Student's t ‐test, H, 40mmHg, t (5) = 2.347, p = 0.0658; 60mmHg, t (5) = 0.2801, p = 0.7906; I, 40mmHg, t (5) = 4.486, p = 0.0065; 60mmHg, t (5) = 3.139, p = 0.0257; Unpaired Student's t ‐test, J, 40mmHg, t (10) = 7.46, p < 0.0001; 60mmHg, t (10) = 4.313, p = 0.0015. (K) Schematic of bilateral anterograde‐DIO (in ACC) and retrograde‐CRE (in AIC) virus injections in OVA rats. (L) Representative image of ACC injection sites. Scale bar, 200 µm. (M,N) C‐fos expression in ACC post‐virus injection. Representative images of colocalization in (M), statistical results in (N), Scale bar, 20 µm (unpaired Student's t ‐test, N, t (10) = 0.1144, p = 0.9112). (O‐R) Failure of ACC‐AIC circuit inhibition to reduce OVA‐induced visceral hypersensitivity. Representative external abdominal oblique muscle EMG recordings in (O), analysis of the mean amplitude of △EMG in (P‐R) (paired Student's t ‐test, P, 40mmHg, t (5) = 0.4976, p = 0.6399; 60mmHg, t (5) = 0.2252, p = 0.8308; Q, 40mmHg, t (5) = 0.9588, p = 0.3817; 60mmHg, t (5) = 0.7854, p = 0.4678; unpaired Student's t ‐test, R, 40mmHg, t (10) = 0.5248, p = 0.6111; 60mmHg, t (10) = 0.1117, p = 0.9132). Data presented as mean ± SEM ( n = 8 rats for the NC group and n = 6 rats for all other groups). * p < 0.05, ** p < 0.01, *** p < 0.001, **** p < 0.0001.

Journal: Advanced Science

Article Title: An Anterior Cingulate Cortex‐Anterior Insular Cortex Glutamatergic Circuit Gates Stress‐Induced Visceral Hypersensitivity and Anxiety via Ionotropic Glutamate Receptors Trafficking

doi: 10.1002/advs.76298

Figure Lengend Snippet: Inhibition of the ACC Glu ‐AIC Glu pathway fails to alleviate visceral hypersensitivity in a non‐mental stress model. (A,B) VMR to 40 and 60mmHg CRD stimulation. OVA: ovalbumin. Representative external abdominal oblique muscle EMG recordings in (A), analysis of the mean amplitude of △EMG in (B) (one‐way ANOVA test followed by Tukey's post‐hoc test, B, 40mmHg, F (2, 17) = 67.67, p < 0.0001; Kruskal–Wallis test followed by Dunnett's post‐hoc test, B, 60mmHg, p = 0.0003. (C) Schematic of bilateral rAAV virus injections in ACC of OVA rats. (D) Representative image of ACC injection sites. Scale bar, 200 µm. (E,F) C‐fos expression in ACC post‐virus injection. Representative images of colocalization in (E), statistical results in (F), Scale bar, 20 µm (unpaired Student's t ‐test, F, t (10) = 8.202, p < 0.0001). (G–J) Inhibition of ACC Glu relieves the visceral hypersensitivity induced by OVA. Representative external abdominal oblique muscle EMG recordings in (G), analysis of the mean amplitude of △EMG in (H–J) (Paired Student's t ‐test, H, 40mmHg, t (5) = 2.347, p = 0.0658; 60mmHg, t (5) = 0.2801, p = 0.7906; I, 40mmHg, t (5) = 4.486, p = 0.0065; 60mmHg, t (5) = 3.139, p = 0.0257; Unpaired Student's t ‐test, J, 40mmHg, t (10) = 7.46, p < 0.0001; 60mmHg, t (10) = 4.313, p = 0.0015. (K) Schematic of bilateral anterograde‐DIO (in ACC) and retrograde‐CRE (in AIC) virus injections in OVA rats. (L) Representative image of ACC injection sites. Scale bar, 200 µm. (M,N) C‐fos expression in ACC post‐virus injection. Representative images of colocalization in (M), statistical results in (N), Scale bar, 20 µm (unpaired Student's t ‐test, N, t (10) = 0.1144, p = 0.9112). (O‐R) Failure of ACC‐AIC circuit inhibition to reduce OVA‐induced visceral hypersensitivity. Representative external abdominal oblique muscle EMG recordings in (O), analysis of the mean amplitude of △EMG in (P‐R) (paired Student's t ‐test, P, 40mmHg, t (5) = 0.4976, p = 0.6399; 60mmHg, t (5) = 0.2252, p = 0.8308; Q, 40mmHg, t (5) = 0.9588, p = 0.3817; 60mmHg, t (5) = 0.7854, p = 0.4678; unpaired Student's t ‐test, R, 40mmHg, t (10) = 0.5248, p = 0.6111; 60mmHg, t (10) = 0.1117, p = 0.9132). Data presented as mean ± SEM ( n = 8 rats for the NC group and n = 6 rats for all other groups). * p < 0.05, ** p < 0.01, *** p < 0.001, **** p < 0.0001.

Article Snippet: Briefly, rats were sensitized to OVA by intraperitoneal injection of a solution containing OVA (100μg, MCE, Monmouth Junction, NJ, USA) as the antigen and aluminum hydroxide (10mg, MCE, Monmouth Junction, NJ, USA) as an adjuvant in 1mL saline.

Techniques: Inhibition, Virus, Injection, Expressing