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Targeted therapies for driver genes in lung adenocarcinoma and lung squamous cell carcinoma.

Journal: Genes & Diseases

Article Title: Differences between lung adenocarcinoma and lung squamous cell carcinoma: Driver genes, therapeutic targets, and clinical efficacy

doi: 10.1016/j.gendis.2024.101374

Figure Lengend Snippet: Targeted therapies for driver genes in lung adenocarcinoma and lung squamous cell carcinoma.

Article Snippet: , Alflutinib , Listed , NCT03452592 , Alflutinib , 220 , NA , 9.6 , 74.0% , Allist Pharmaceuticals, Inc..

Techniques:

Summary of first, second, third and fourth generation of EGFR-TKIs

Journal: Journal of Cell Communication and Signaling

Article Title: Role of EGFR and FASN in breast cancer progression

doi: 10.1007/s12079-023-00771-w

Figure Lengend Snippet: Summary of first, second, third and fourth generation of EGFR-TKIs

Article Snippet: , Alflutinib (AST2818) was approved in China in March 3, 2021 , C797S , Shanghai Allist Pharmaceuticals , Irreversible inhibitor of exo19del or L858R, and T790M mutation , NA , , Murtuza et al. ( 2019 ).

Techniques: Inhibition, Binding Assay, Mutagenesis

Comparison of the structure of furmonertinib and osimertinib.

Journal: Lung Cancer: Targets and Therapy

Article Title: Spotlight on Furmonertinib (Alflutinib, AST2818). The Swiss Army Knife (del19, L858R, T790M, Exon 20 Insertions, “uncommon-G719X, S768I, L861Q”) Among the Third-Generation EGFR TKIs?

doi: 10.2147/LCTT.S385437

Figure Lengend Snippet: Comparison of the structure of furmonertinib and osimertinib.

Article Snippet: Furmonertinib (AST2818, Alflutinib) is manufactured by Shanghai Allist Pharmaceuticals Co., Ltd. in Shanghai, China.

Techniques: Comparison

Comparison of Incidence of QTc Prolongation Between Furmonertinib and Osimertinib

Journal: Lung Cancer: Targets and Therapy

Article Title: Spotlight on Furmonertinib (Alflutinib, AST2818). The Swiss Army Knife (del19, L858R, T790M, Exon 20 Insertions, “uncommon-G719X, S768I, L861Q”) Among the Third-Generation EGFR TKIs?

doi: 10.2147/LCTT.S385437

Figure Lengend Snippet: Comparison of Incidence of QTc Prolongation Between Furmonertinib and Osimertinib

Article Snippet: Furmonertinib (AST2818, Alflutinib) is manufactured by Shanghai Allist Pharmaceuticals Co., Ltd. in Shanghai, China.

Techniques: Comparison