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Tiered workflow and decision tree for integrating rapid electroencephalography (EEG) with artificial intelligence (AI) from prehospital screening to emergency department (ED) confirmation. This figure is intended as a conceptual workflow rather than a study-by-study evidence map. (A) Prehospital pathway: In cases of suspected status epilepticus (SE), nonconvulsive status epilepticus (NCSE), or unexplained altered mental status (AMS), rapid EEG is initiated after airway–breathing–circulation (ABC) stabilization. If quality control (QC) is inadequate, electrodes are adjusted and recording repeated. <t>Interpretable</t> <t>AI-based</t> clinical decision support (CDS) detects electrographic seizures or highly epileptiform patterns (HEP); high-risk outputs prompt pre-notification without delaying benzodiazepines. (B) ED decision tree: Upon ED arrival, rapid EEG is started promptly. EEG/AI outputs are integrated with clinical data to stratify patients into high-, intermediate-, or low-risk categories, guiding escalation, monitoring, and disposition decisions as shown. Risk thresholds and action protocols require calibration to specific device performance and local workflows; AI outputs function as decision support and must be interpreted within the clinical context.
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Tiered workflow and decision tree for integrating rapid electroencephalography (EEG) with artificial intelligence (AI) from prehospital screening to emergency department (ED) confirmation. This figure is intended as a conceptual workflow rather than a study-by-study evidence map. (A) Prehospital pathway: In cases of suspected status epilepticus (SE), nonconvulsive status epilepticus (NCSE), or unexplained altered mental status (AMS), rapid EEG is initiated after airway–breathing–circulation (ABC) stabilization. If quality control (QC) is inadequate, electrodes are adjusted and recording repeated. <t>Interpretable</t> <t>AI-based</t> clinical decision support (CDS) detects electrographic seizures or highly epileptiform patterns (HEP); high-risk outputs prompt pre-notification without delaying benzodiazepines. (B) ED decision tree: Upon ED arrival, rapid EEG is started promptly. EEG/AI outputs are integrated with clinical data to stratify patients into high-, intermediate-, or low-risk categories, guiding escalation, monitoring, and disposition decisions as shown. Risk thresholds and action protocols require calibration to specific device performance and local workflows; AI outputs function as decision support and must be interpreted within the clinical context.
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Tiered workflow and decision tree for integrating rapid electroencephalography (EEG) with artificial intelligence (AI) from prehospital screening to emergency department (ED) confirmation. This figure is intended as a conceptual workflow rather than a study-by-study evidence map. (A) Prehospital pathway: In cases of suspected status epilepticus (SE), nonconvulsive status epilepticus (NCSE), or unexplained altered mental status (AMS), rapid EEG is initiated after airway–breathing–circulation (ABC) stabilization. If quality control (QC) is inadequate, electrodes are adjusted and recording repeated. Interpretable AI-based clinical decision support (CDS) detects electrographic seizures or highly epileptiform patterns (HEP); high-risk outputs prompt pre-notification without delaying benzodiazepines. (B) ED decision tree: Upon ED arrival, rapid EEG is started promptly. EEG/AI outputs are integrated with clinical data to stratify patients into high-, intermediate-, or low-risk categories, guiding escalation, monitoring, and disposition decisions as shown. Risk thresholds and action protocols require calibration to specific device performance and local workflows; AI outputs function as decision support and must be interpreted within the clinical context.

Journal: Frontiers in Neurology

Article Title: From prehospital care to the emergency department: current status and future directions of rapid EEG and artificial intelligence in the early recognition of status epilepticus

doi: 10.3389/fneur.2026.1806106

Figure Lengend Snippet: Tiered workflow and decision tree for integrating rapid electroencephalography (EEG) with artificial intelligence (AI) from prehospital screening to emergency department (ED) confirmation. This figure is intended as a conceptual workflow rather than a study-by-study evidence map. (A) Prehospital pathway: In cases of suspected status epilepticus (SE), nonconvulsive status epilepticus (NCSE), or unexplained altered mental status (AMS), rapid EEG is initiated after airway–breathing–circulation (ABC) stabilization. If quality control (QC) is inadequate, electrodes are adjusted and recording repeated. Interpretable AI-based clinical decision support (CDS) detects electrographic seizures or highly epileptiform patterns (HEP); high-risk outputs prompt pre-notification without delaying benzodiazepines. (B) ED decision tree: Upon ED arrival, rapid EEG is started promptly. EEG/AI outputs are integrated with clinical data to stratify patients into high-, intermediate-, or low-risk categories, guiding escalation, monitoring, and disposition decisions as shown. Risk thresholds and action protocols require calibration to specific device performance and local workflows; AI outputs function as decision support and must be interpreted within the clinical context.

Article Snippet: AI-based language tools (Grammarly) were used for grammar correction and readability improvement during manuscript preparation.

Techniques: Control