Journal: Vox Sanguinis

Article Title: Viscoelastic haemostatic assays in chronic liver disease—Profiling coagulation in the emergency department

doi: 10.1111/vox.70167

Figure Lengend Snippet: (a) Violin plots of rotational thromboelastometry (ROTEM) parameters ( n = 397). Blue violins show distributions with individual values (crosses), annotated medians and interquartile ranges (IQRs) and red shaded reference ranges. (b) Violin plots of thromboelastogram (TEG) parameters ( n = 397). Blue violins show distributions with individual values (crosses), annotated medians and IQRs and red shaded reference ranges. A10, amplitude 10 min after start of clotting time (CT); CFF, clot formation time; CK R, clotting time (R‐time) in citrated kaolin channel of TEG 6s; CRT, clot reaction time; EXTEM, extrinsically activated thromboelastometry; FIBTEM, fibrin‐based thromboelastometry; LY30, lysis 30 min after maximum amplitude; MA, maximum amplitude; ML, maximum lysis.

Article Snippet: ROTEM: FIBTEM A10 ≥ 11 mm + EXTEM A10 < 43 mm , 45 (11.3%) , 3 (7.3%).

Techniques: Coagulation, FIBTEM Assay, Lysis

Journal: Vox Sanguinis

Article Title: Viscoelastic haemostatic assays in chronic liver disease—Profiling coagulation in the emergency department

doi: 10.1111/vox.70167

Figure Lengend Snippet: (a) Patient‐level combinations of fibrinogen, platelet and coagulation factor deficiencies, and hyperfibrinolysis in rotational thromboelastometry (ROTEM) ( n = 397). (b) Patient‐level combinations of fibrinogen, platelet and coagulation factor deficiencies, and hyperfibrinolysis in thromboelastogram (TEG) ( n = 41). A10, amplitude 10 min after start of clotting time (CT); CFF, clot formation time; CK R, clotting time (R‐time) in citrated kaolin channel of TEG 6s; CRT, clot reaction time; EXTEM, extrinsically activated thromboelastometry; FIBTEM, fibrin‐based thromboelastometry; LY30, lysis 30 min after maximum amplitude; MA, maximum amplitude; ML, maximum lysis.

Article Snippet: ROTEM: FIBTEM A10 ≥ 11 mm + EXTEM A10 < 43 mm , 45 (11.3%) , 3 (7.3%).

Techniques: Coagulation, FIBTEM Assay, Lysis

Journal: Vox Sanguinis

Article Title: Viscoelastic haemostatic assays in chronic liver disease—Profiling coagulation in the emergency department

doi: 10.1111/vox.70167

Figure Lengend Snippet: Concordance of fibrinogen, platelet and coagulation factor deficiencies detected by viscoelastic haemostatic assay (VHA) and conventional coagulation test (CCT) in paired samples ( n = 120). Rotational thromboelastometry (ROTEM) and thromboelastogram (TEG) were combined. Definitions: Fibrinogen—ROTEM: Fibrin‐based thromboelastometry (FIBTEM) amplitude 10 min after start of clotting time (CT) (A10) <11 mm; TEG: citrated functional fibrinogen (CFF) maximum amplitude (MA) <15 mm; CCT: Fibrinogen <1.0 g/L. Platelet—ROTEM: FIBTEM A10 ≥11 mm + extrinsically activated thromboelastometry (EXTEM) A10 <43 mm; TEG: CFF MA ≥15 mm + clot reaction time (CRT) MA <50 mm; CCT: Platelets <50 × 10 9 /L. Coagulation factor—ROTEM: EXTEM CT >80 s; TEG: Clotting time (R‐time) in citrated kaolin channel of TEG 6s (CK R) > 9 min; CCT: international normalized ratio (INR) >1.5.

Article Snippet: ROTEM: FIBTEM A10 ≥ 11 mm + EXTEM A10 < 43 mm , 45 (11.3%) , 3 (7.3%).

Techniques: Coagulation, FIBTEM Assay, Functional Assay

Journal: Transfusion

Article Title: Adherence to local rotational thromboelastometry recommendations in the care of trauma patients: A retrospective cohort study

doi: 10.1111/trf.18349

Figure Lengend Snippet: Number of rotational thromboelastometry (ROTEM) abnormalities per patient on first ROTEM read across cohort ( N = 446).

Article Snippet: ROTEM EXTEM A10, mean (SD) , 51.13 (11.79) , 56.47 (7.39) , 46.43 (12.96) , 0.952.

Techniques:

Journal: Thrombosis Journal

Article Title: Point of care diagnostic of hypercoagulability and platelet function in COVID-19 induced acute respiratory distress syndrome: a retrospective observational study

doi: 10.1186/s12959-021-00293-8

Figure Lengend Snippet: Rotem® and Multiplate® results in ICU patients (total n = 18)

Article Snippet: Rotem® Delta ∆A10 (EXTEM minus FIBTEM) [mm] ∆MCF (EXTEM minus FIBTEM) [mm] , 33 (27–36) 36 (29–37) , 24 (19–35) 29 (22–36) , 29 (23–33) 28 (23–35) , 30 (24–36) 33 (25–40).

Techniques: FIBTEM Assay

Journal: Thrombosis Journal

Article Title: Point of care diagnostic of hypercoagulability and platelet function in COVID-19 induced acute respiratory distress syndrome: a retrospective observational study

doi: 10.1186/s12959-021-00293-8

Figure Lengend Snippet: Platelet aggregation ability by Multiplate®. Correlation between ∆A10 (EXTEM minus FIBTEM) and platelet count, mean platelet volume and platelet aggregation ability (Multiplate® with TRAP-6 and ADP). a ∆A10 vs. platelet count. b ∆A10 vs. mean platelet volume. c ∆A10 vs. Multiplate® with agonist TRAP-6. d ∆A10 vs. Multiplate® with agonist ADP. Values are presented during the course of ICU stay for day 1 (●), day 4 (■), day 7 (▲) and day 14 (▼) respectively. Spearman correlation coefficient is displayed by r s . Reference values for platelet count, mean platelet volume, TRAP-6 and ADP are indicated by pink boxes

Article Snippet: Rotem® Delta ∆A10 (EXTEM minus FIBTEM) [mm] ∆MCF (EXTEM minus FIBTEM) [mm] , 33 (27–36) 36 (29–37) , 24 (19–35) 29 (22–36) , 29 (23–33) 28 (23–35) , 30 (24–36) 33 (25–40).

Techniques: FIBTEM Assay

Journal: Thrombosis Journal

Article Title: Point of care diagnostic of hypercoagulability and platelet function in COVID-19 induced acute respiratory distress syndrome: a retrospective observational study

doi: 10.1186/s12959-021-00293-8

Figure Lengend Snippet: Typical examples of Rotem® INTEM, EXTEM and FIBTEM measurements for a COVID-19 ARDS patient and a healthy control. Typical examples of Rotem® INTEM, EXTEM and FIBTEM measurements for a COVID-19 ARDS patient and a healthy control. Units are displayed in square brackets and reference values in round brackets. Abnormal values are presented in red. Abbreviations: Clotting Time (CT), Clot Formation Time (CFT), Amplitude 10 min after CT (A10), Maximum Clot Firmness (MCF), Lysis Index 30 min (LI30).

Article Snippet: Rotem® Delta ∆A10 (EXTEM minus FIBTEM) [mm] ∆MCF (EXTEM minus FIBTEM) [mm] , 33 (27–36) 36 (29–37) , 24 (19–35) 29 (22–36) , 29 (23–33) 28 (23–35) , 30 (24–36) 33 (25–40).

Techniques: FIBTEM Assay, Control, Coagulation, Lysis