Journal: bioRxiv

Article Title: Early life stress of maternal deprivation and peer-rearing jeopardize mesoprefrontal and mesolimbic dopamine receptors in the rhesus monkey

doi: 10.64898/2026.02.28.708755

Figure Lengend Snippet:

Article Snippet: After being dipped in cold ddH2O, the slide-mounted sections were immediately dried, using a cool stream of air, for approximately 15 min. Then, both autoradiographic 125I microscale standards (Amersham Life Science, Inc., www.amersham.com ) and the 125 I-Epidepride labeled sections were apposed to Kodak BiomaxMR X-ray film (Kodak, www.kodak.com ) for 1-3 days.

Techniques: Binding Assay

Journal: bioRxiv

Article Title: Early life stress of maternal deprivation and peer-rearing jeopardize mesoprefrontal and mesolimbic dopamine receptors in the rhesus monkey

doi: 10.64898/2026.02.28.708755

Figure Lengend Snippet: (A): A pair of rhesus monkey autoradiograms from one mother-reared (MR) subject “RMC7” and one nursery-reared (NR) subject “RGZ6” illustrate [125I]-(+)-SCH 23982 binding for Dopamine Receptor-1 (DRD1) within the orbital prefrontal cortex (oPFC, indicated by arrow in bottom image). (B) : While not significantly different in the medial or dorsolateral areas of the prefrontal cortex monkeys significantly differed in the degree of DRD1 (dpm/mg) binding within the oPFC. MR (N=6) monkeys possessed greater DRD1 than NR (N=6) monkeys (1-Tail, RMANOVA, F (1, 11) = 4.138, p<.05, η2 = 0.293).

Article Snippet: After being dipped in cold ddH2O, the slide-mounted sections were immediately dried, using a cool stream of air, for approximately 15 min. Then, both autoradiographic 125I microscale standards (Amersham Life Science, Inc., www.amersham.com ) and the 125 I-Epidepride labeled sections were apposed to Kodak BiomaxMR X-ray film (Kodak, www.kodak.com ) for 1-3 days.

Techniques: Binding Assay