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Modules and gene assessed with Endopredict test.

Journal: Molecular Carcinogenesis

Article Title: Evaluation and Comparison of Prognostic Multigene Tests in Early‐Stage Breast Cancer: Which Is the Most Effective? A Literature Review Exploring Clinical Utility to Enhance Therapeutic Management in Luminal Patients

doi: 10.1002/mc.23893

Figure Lengend Snippet: Modules and gene assessed with Endopredict test.

Article Snippet: ENDOPREDICT (12 GENES) EndoPredict (Myriad Genetics, Salt Lake City, UT, USA) is a second‐generation RNA‐based 12‐gene expression test that determines the 10‐year absolute CT benefit for patients with ER+/HER2‐primary breast cancer as well as the risk of distant recurrence up to 15 years [ ].

Techniques:

Summary of Original Recommendations for Question 1 With Focused Updated Recommendations

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Article Title: Use of Biomarkers to Guide Decisions on Adjuvant Systemic Therapy for Women With Early-Stage Invasive Breast Cancer: American Society of Clinical Oncology Clinical Practice Guideline Focused Update

doi: 10.1200/JCO.2017.74.0472

Figure Lengend Snippet: Summary of Original Recommendations for Question 1 With Focused Updated Recommendations

Article Snippet: 1.6 , If a patient has HER2-positive breast cancer or triple-negative breast cancer, the clinician should not use 12-gene risk score (EndoPredict; Sividon Diagnostics) to guide decisions for adjuvant systemic therapy. , Type: informal consensus Evidence quality: insufficient Strength of recommendation: strong.

Techniques: Adjuvant, Labeling, Immunohistochemistry, Gene Expression