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web-based platform system  (MedSciNet UK Ltd)

 
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    MedSciNet UK Ltd web-based platform system
    Web Based Platform System, supplied by MedSciNet UK Ltd, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/web-based+platform/web+based+platform/pm37248450-74-13-13
    Average 90 stars, based on 1 article reviews
    web-based platform system - by Bioz Stars, 2026-09
    90/100 stars

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    Related Articles

    other:

    Article Title: Treatments for unruptured intracranial aneurysms
    Article Snippet: Background Unruptured intracranial aneurysms are relatively common lesions in the general population, with a prevalence of 3.2%, and are being diagnosed with greater frequency as non-invasive techniques for imaging of intracranial vessels have become increasingly available and used.. If not treated, an intracranial aneurysm can be catastrophic.. Morbidity and mortality in aneurysmal subarachnoid hemorrhage are substantial: in people with subarachnoid hemorrhage, 12% die immediately, more than 30% die within one month, 25% to 50% die within six months, and 30% of survivors remain dependent.

    Article Title: Treatments for unruptured intracranial aneurysms
    Article Snippet: Allocation concealment (selection bias) , Low risk , Randomization was concealed, generated through a web‐based platform (MedSciNet)..

    Article Title: Treatments for unruptured intracranial aneurysms
    Article Snippet: Darsaut 2017 had a parallel‐group randomization (1:1), which was concealed and generated through a web‐based platform (MedSciNet). . Blinding The study design and the nature of the intervention and outcomes were such that health workers and participants were not blinded to treatment in either study. .

    Article Title: Treatments for unruptured intracranial aneurysms
    Article Snippet: Darsaut 2017 had a parallel‐group randomization (1:1), which was concealed and generated through a web‐based platform (MedSciNet).

    Article Title: Treatments for unruptured intracranial aneurysms
    Article Snippet: Allocation concealment (selection bias) Low risk Randomization was concealed, generated through a web‐based platform (MedSciNet).

    Article Title: Measuring resilience and stress during pregnancy and its relation to vulnerability and pregnancy outcomes in a nulliparous cohort study.
    Article Snippet: Standardized and validated (self-administered) instruments were applied and records were transcribed to the MedSciNet web-based platform system.

    Generated:

    Article Title: A Pragmatic Randomized Trial Comparing Surgical Clipping and Endovascular Treatment of Unruptured Intracranial Aneurysms
    Article Snippet: .. Randomization Parallel-group randomization (1:1) was concealed, generated through a webbased platform (https://www.medscinet. com/cures), and minimized for age older than 60 years, aneurysm size of$15mm, and posterior circulation location (posterior communicating artery aneurysms were considered to be in the anterior circulation). ..

    Article Title: A Pragmatic Randomized Trial Comparing Surgical Clipping and Endovascular Treatment of Unruptured Intracranial Aneurysms
    Article Snippet: .. Parallel-group randomization (1:1) was concealed, generated through a webbased platform (https://www.medscinet. com/cures), and minimized for age older than 60 years, aneurysm size of$15mm, and posterior circulation location (posterior communicating artery aneurysms were considered to be in the anterior circulation). ..



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    a , Schematic of the CRISPR–Cas9 knockout strategy targeting slc45a2 , designed to induce a visible pigmentation-loss phenotype for screening. Representative brightfield images of 6 and 21 dpf WT and cr slc45a2 zebrafish show loss of melanin pigmentation in mutants. b , Schematic of CRISPR guide RNA target sites (aa and ab) on the slc45a2 gene with representative Sanger sequencing traces and ICE analysis of indels from 7 dpf larvae injected at the one-cell stage with both guides. c , Indel efficiency rates for each slc45a2 CRISPR target site. d , Schematic of CRISPR guide RNA target sites (aa and ab) on the tgr5 gene with representative Sanger sequencing traces and ICE analysis from 7 dpf larvae co-injected at the one-cell stage with tgr5 and slc45a2 guides (latter not shown). e , Indel efficiency rates for each tgr5 CRISPR target site. f , Schematic of the CRISPR target site (ab) on cyp7a1 with corresponding Sanger sequencing traces and ICE analysis from 7 dpf larvae co-injected at the one-cell stage with cyp7a1 and slc45a2 guides (latter not shown). g , Indel efficiency rates for the cyp7a1 CRISPR target site. h-k , Biometrics of body length ( h , standard length, SL), muscle width ( i ), liver size ( j ) and adipose tissue size ( k ) in WT cr slc45a2 , WT cr tgr5 and WT cr cyp7a1 zebrafish at 21 dpf. l , Heat map of selected adipogenic, lipolytic, myogenic, proteolytic and inflammatory gene expression profiles in pooled WT, crslc45a2 , crtgr5 and crcyp7a1 zebrafish at 21 dpf, determined by bulk RNA-seq (n = 4 samples of 5 fish per condition). All data are mean ± s.e.m. P values were determined by one-way ANOVA with Tukey’s multiple-comparisons test ( h,i ) and Kruskal–Wallis test with Dunn’s multiple-comparisons post hoc adjustment ( j,k ). *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001.

    Journal: bioRxiv

    Article Title: YAP disrupts bile acid homeostasis to drive cancer-associated cachexia

    doi: 10.64898/2026.02.01.702698

    Figure Lengend Snippet: a , Schematic of the CRISPR–Cas9 knockout strategy targeting slc45a2 , designed to induce a visible pigmentation-loss phenotype for screening. Representative brightfield images of 6 and 21 dpf WT and cr slc45a2 zebrafish show loss of melanin pigmentation in mutants. b , Schematic of CRISPR guide RNA target sites (aa and ab) on the slc45a2 gene with representative Sanger sequencing traces and ICE analysis of indels from 7 dpf larvae injected at the one-cell stage with both guides. c , Indel efficiency rates for each slc45a2 CRISPR target site. d , Schematic of CRISPR guide RNA target sites (aa and ab) on the tgr5 gene with representative Sanger sequencing traces and ICE analysis from 7 dpf larvae co-injected at the one-cell stage with tgr5 and slc45a2 guides (latter not shown). e , Indel efficiency rates for each tgr5 CRISPR target site. f , Schematic of the CRISPR target site (ab) on cyp7a1 with corresponding Sanger sequencing traces and ICE analysis from 7 dpf larvae co-injected at the one-cell stage with cyp7a1 and slc45a2 guides (latter not shown). g , Indel efficiency rates for the cyp7a1 CRISPR target site. h-k , Biometrics of body length ( h , standard length, SL), muscle width ( i ), liver size ( j ) and adipose tissue size ( k ) in WT cr slc45a2 , WT cr tgr5 and WT cr cyp7a1 zebrafish at 21 dpf. l , Heat map of selected adipogenic, lipolytic, myogenic, proteolytic and inflammatory gene expression profiles in pooled WT, crslc45a2 , crtgr5 and crcyp7a1 zebrafish at 21 dpf, determined by bulk RNA-seq (n = 4 samples of 5 fish per condition). All data are mean ± s.e.m. P values were determined by one-way ANOVA with Tukey’s multiple-comparisons test ( h,i ) and Kruskal–Wallis test with Dunn’s multiple-comparisons post hoc adjustment ( j,k ). *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001.

    Article Snippet: Indels in the sequenced data were analysed using the Inference of CRISPR Edits (ICE) web-based platform (Synthego).

    Techniques: CRISPR, Knock-Out, Sequencing, Injection, Gene Expression, RNA Sequencing