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PeproTech rhil-21
Rhil 21, supplied by PeproTech, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/rhil-+21/rhil+21/pmc11556684-94-39-42
Average 90 stars, based on 1 article reviews
rhil-21 - by Bioz Stars, 2026-09
90/100 stars

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Article Title: TRAIL-dependent apoptosis of peritoneal mesothelial cells by NK cells promotes ovarian cancer invasion
Article Snippet: In individual experiments, NK cells were treated with the following cytokines – alone or in combination – for two days: 10 ng/mL rh-TNFα (PeproTech, Hamburg, Germany), 10 ng/mL rh-IFNγ (Biomol), 20 ng/mL rh-IL-2 (ImmunoTools, Friesoythe, Germany), and 10 ng/mL rh-IL-21 (PeproTech).

Article Title: Defective peripheral B cell selection in common variable immune deficiency patients with autoimmune manifestations.
Article Snippet: Sorted naive B cells were stimulated 1 mg/mL rhCD40L (Enzo Life Sciences) plus 10 mg/mL anti-IgM/IgG/IgA (Jackson Immunoresearch) and 20 ng/mL rhIL-21 (Peprotech) in complete medium at a concentration of 2.5x106 cells/ml for 48 h.

Article Title: Intensified NK cell therapy in combination with low-dose chemoradiotherapy against human colorectal cancer
Article Snippet: The medium was replaced every 2–3 days with fresh RPMI 1640 medium supplemented with 10 U/mL rhIL-2 and 5 ng/mL rhIL-21 (PeproTech, Rocky Hill, NJ, USA).

Article Title: Generation of primary feline chimeric antigen receptor T cells.
Article Snippet: 1 X 105 enriched T cells/well were seeded in 100 μL of complete XVIVO-15 in 96-well round-bottom tissue culture plates (Thermo) with 10 ng/mL rfIL-2 (R&D Systems) alone or in combination with 100 ng/mL recombinant human IL-21 (rhIL-21; Peprotech), 5 μg/ mL ConA (Sigma), or 25 ng/mL PMA (Sigma) + 1 μg/ mL ionomycin (Sigma) for 24 hours.

Article Title: A clinically-relevant STING agonist restrains human T H 17 cell inflammatory profile.
Article Snippet: The STING signaling pathway has gained attention over the last few years due to its ability to incite antimicrobial and antitumoral immunity.. Conversely, in mouse models of autoimmunity such as colitis and multiple sclerosis, where TH17 cells are implicated in tissue inflammation, STING activation has been associated with the attenuation of immunogenic responses.. In this line, STING was found to limit murine TH17 pro-inflammatory program in vitro.

Article Title: TRAIL-dependent apoptosis of peritoneal mesothelial cells by NK cells promotes ovarian cancer invasion
Article Snippet: rh-IL-21 , PeproTech , Cat# 200-21.

Article Title: B cell receptor dependent enhancement of dengue virus infection
Article Snippet: Both 7B9 and 2F3 cells were generated by transduction of IgM–CD27+ memory B cells with a retrovirus encoding human B cell lymphoma (BCL)-6 and BCL-xL and enhanced green fluorescent protein (GFP) and culture on CD40L-expressing L cell fibroblasts and rhIL-21 (25 ng/mL, Peprotech) as described [ ].

Article Title: Intensified NK cell therapy in combination with low-dose chemoradiotherapy against human colorectal cancer.
Article Snippet: The therapeutic potential of adoptive natural Killer (NK) cells immunotherapy in combination with chemoradiotherapy, the main treatment modality for colorectal cancer (CRC), has not yet been explored.. Here, we aimed to investigate the efficacy of NK cells to potentiate primary tumor control and improve survival outcomes, especially in combination with low-dose chemoradiotherapy.. Ex vivo activated NK cells (> 90% purity) from healthy donors were obtained.

Transduction:

Article Title: TRAIL-dependent apoptosis of peritoneal mesothelial cells by NK cells promotes ovarian cancer invasion
Article Snippet: In individual experiments, NK cells were treated with the following cytokines – alone or in combination – for two days: 10 ng/mL rh-TNFα (PeproTech, Hamburg, Germany), 10 ng/mL rh-IFNγ (Biomol), 20 ng/mL rh-IL-2 (ImmunoTools, Friesoythe, Germany), and 10 ng/mL rh-IL-21 (PeproTech).

Article Title: Defective peripheral B cell selection in common variable immune deficiency patients with autoimmune manifestations.
Article Snippet: Sorted naive B cells were stimulated 1 mg/mL rhCD40L (Enzo Life Sciences) plus 10 mg/mL anti-IgM/IgG/IgA (Jackson Immunoresearch) and 20 ng/mL rhIL-21 (Peprotech) in complete medium at a concentration of 2.5x106 cells/ml for 48 h.

Article Title: Intensified NK cell therapy in combination with low-dose chemoradiotherapy against human colorectal cancer
Article Snippet: The medium was replaced every 2–3 days with fresh RPMI 1640 medium supplemented with 10 U/mL rhIL-2 and 5 ng/mL rhIL-21 (PeproTech, Rocky Hill, NJ, USA).

Article Title: Generation of primary feline chimeric antigen receptor T cells.
Article Snippet: 1 X 105 enriched T cells/well were seeded in 100 μL of complete XVIVO-15 in 96-well round-bottom tissue culture plates (Thermo) with 10 ng/mL rfIL-2 (R&D Systems) alone or in combination with 100 ng/mL recombinant human IL-21 (rhIL-21; Peprotech), 5 μg/ mL ConA (Sigma), or 25 ng/mL PMA (Sigma) + 1 μg/ mL ionomycin (Sigma) for 24 hours.

Article Title: A clinically-relevant STING agonist restrains human T H 17 cell inflammatory profile.
Article Snippet: The STING signaling pathway has gained attention over the last few years due to its ability to incite antimicrobial and antitumoral immunity.. Conversely, in mouse models of autoimmunity such as colitis and multiple sclerosis, where TH17 cells are implicated in tissue inflammation, STING activation has been associated with the attenuation of immunogenic responses.. In this line, STING was found to limit murine TH17 pro-inflammatory program in vitro.

Article Title: TRAIL-dependent apoptosis of peritoneal mesothelial cells by NK cells promotes ovarian cancer invasion
Article Snippet: rh-IL-21 , PeproTech , Cat# 200-21.

Article Title: B cell receptor dependent enhancement of dengue virus infection
Article Snippet: Both 7B9 and 2F3 cells were generated by transduction of IgM–CD27+ memory B cells with a retrovirus encoding human B cell lymphoma (BCL)-6 and BCL-xL and enhanced green fluorescent protein (GFP) and culture on CD40L-expressing L cell fibroblasts and rhIL-21 (25 ng/mL, Peprotech) as described [ ].

Article Title: Intensified NK cell therapy in combination with low-dose chemoradiotherapy against human colorectal cancer.
Article Snippet: The therapeutic potential of adoptive natural Killer (NK) cells immunotherapy in combination with chemoradiotherapy, the main treatment modality for colorectal cancer (CRC), has not yet been explored.. Here, we aimed to investigate the efficacy of NK cells to potentiate primary tumor control and improve survival outcomes, especially in combination with low-dose chemoradiotherapy.. Ex vivo activated NK cells (> 90% purity) from healthy donors were obtained.



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