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BIOTAGE pyrosequencer
Pyrosequencer, supplied by BIOTAGE, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/pyrosequencing/pyrosequencer/pm19893579-40-5-6
Average 90 stars, based on 1 article reviews
pyrosequencer - by Bioz Stars, 2026-09
90/100 stars

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Article Title: The Impact of a Single Nucleotide Polymorphism in SIGMAR1 on Depressive Symptoms in Major Depressive Disorder and Bipolar Disorder.
Article Snippet: Introduction: Ample evidence suggested a role of sigma-1 receptor in affective disorders since the interaction of numerous antidepressants with sigma receptors was discovered.. A recent study on Japanese subjects found a genetic variant within the encoding gene SIGMAR1 (rs1800866A[C) associated with major depressive disorder (MDD).. We aimed to evaluate the same polymorphism in both MDD and bipolar disorder (BD) as well as its relationship to response to treatment with antidepressants and mood stabilizers.

Article Title: Genetic Variants Within Key Nodes of the Cascade of Antipsychotic Mechanisms: Effects on Antipsychotic Response and Schizophrenia Psychopathology in a Naturalistic Treatment Setting in Two Independent Korean and Italian Samples.
Article Snippet: Introduction: Schizophrenia (SCZ) is one of the most disabling psychiatric disorders.. Genetic factors play an important role in both SCZ liability and its treatment outcome.. In the present paper, we investigated the effects of several single nucleotide polymorphisms (SNPs) within ten strong candidate genes involved with antipsychotics (APs) mechanisms of action.

Article Title: ZNF804A Gene Variants Have a Cross-diagnostic Influence on Psychosis and Treatment Improvement in Mood Disorders
Article Snippet: For the Korean sample, high-throughput genotyping using a pyrosequencer (Biotage AB, Uppsala, Sweden) was employed to genotype the genomic DNA from subjects blood.

Article Title: Neuroplasticity, Neurotransmission and Brain-Related Genes in Major Depression and Bipolar Disorder: Focus on Treatment Outcomes in an Asiatic Sample
Article Snippet: High-throughput genotyping using a pyrosequencer (Biotage, Sweden) was used to genotype the genomic desossiribonucleic acid (DNA) from blood.

Article Title: Genetic Variants Within Molecular Targets of Antipsychotic Treatment: Effects on Treatment Response, Schizophrenia Risk, and Psychopathological Features.
Article Snippet: Schizophrenia (SCZ) is a common and severe mental disorder.. Genetic factors likely play a role in its pathophysiology as well as in treatment response.. In the present study, we investigated the effects of several single nucleotide polymorphisms (SNPs) within 9 genes involved with antipsychotic (AP) mechanisms of action.

Article Title: Genes Involved in Neurodevelopment, Neuroplasticity, and Bipolar Disorder: CACNA1C, CHRNA1, and MAPK1.
Article Snippet: Background: Bipolar disorder (BPD) is a common and severe mental disorder.. The involvement of genetic factors in the pathophysiology of BPD is well known.. In the present study, we tested the association of several single-nucleotide polymorphisms (SNPs) within 3 strong candidate genes (CACNA1C, CHRNA7, and MAPK1) with BPD.

Article Title: Hot Genes in Schizophrenia: How Clinical Datasets Could Help to Refine their Role.
Article Snippet: We investigated the effect of a set of SNPs within 5 genes identified by GWASs as possible risk genes for schizophrenia (SCZ) in two independent samples, comprising 176 SCZ patients and 326 controls of Korean origin and 83 SCZ patients and 194 controls of Italian origin.. The PANSS was used to assess psychopathology severity and antipsychotic response (AR).. Several clinical features were assessed at recruitment.

Polymerase Chain Reaction:

Article Title: Natural Variation in a Dendritic Scaffold Protein Remodels Experience-Dependent Plasticity by Altering Neuropeptide Expression
Article Snippet: .. Lysates of 2 mL of thewormpellets were used as PCR templates and allele frequencies were quantified with a pyrosequencer (PyroMark Q96 ID; Biotage). ..



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