structural analysis program pymol (DeLano Scientific)
90
Structured Review
DeLano Scientific
structural analysis program pymol
Structural Analysis Program Pymol, supplied by DeLano Scientific, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/pymol+program/structural+analysis+program+pymol/bio_rxiv__475293-55-42-45
Average 90 stars, based on 1 article reviews
Structural Analysis Program Pymol, supplied by DeLano Scientific, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/pymol+program/structural+analysis+program+pymol/bio_rxiv__475293-55-42-45
Average 90 stars, based on 1 article reviews
structural analysis program pymol - by Bioz Stars,
2026-10
90/100 stars
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1) Product Images from "Activation of Multiple Signalling Pathways by P152Lp53 Mutant Reveals New Gain-of-function Implicating Tumorigenesis"
Article Title: Activation of Multiple Signalling Pathways by P152Lp53 Mutant Reveals New Gain-of-function Implicating Tumorigenesis
Journal: bioRxiv
doi: 10.1101/475293
Figure Legend Snippet: (a) Immunohistochemistry for mutant p53 by PAb240 antibody (indicated by →) on oral cancer sample, (b) Sequence chromatogram showing C>T substitution at 152 position, (c) location of P152 (shown in pink) in 3-D structure of p53 core domain bound to DNA visualized by PyMol (molecular visualization software), (d) Multiple sequence alignment of human TP53 protein sequence across various organism. The P152 residue is indicated by a black arrow, (e) Prevalence of missence mutations in a strecth of 150-155amino acid of p53 analyzed from COSMIC database version 86, (f) Bar plot representation of number and frequency of various missense mutation present at TP53 (P152) loci out of 111 samples available data at COSMIC. The percentage frequency of various amino acid substitutions are shown above the bars. (g) Bar plot representation of number and frequency distribution of TP53 (P152L) mutation occurrence over various cancer tissue type out of 111 samples of P152L mutations. CNS: central nervous system, others: adrenal gland, breast, haematopoietic and lymphoid tissue, liver, lung, pancreas, skin, soft tissue and stomach tissue.
Techniques Used: Immunohistochemistry, Mutagenesis, Sequencing, Software, Residue
Related Articles
Mutagenesis:Article Title: Activation of Multiple Signalling Pathways by P152Lp53 Mutant Reveals New Gain-of-function Implicating Tumorigenesis Article Snippet: To model the location of proline at position 152 of p53, coordinates of the human p53 DNA-binding domain bound to DNA with Article Title: The cancer-associated, gain-of-function TP53 variant P152Lp53 activates multiple signaling pathways implicated in tumorigenesis Article Snippet: To model the location of proline at position 152 of p53, coordinates of the human p53 DNA-binding domain bound to DNA with Article Title: The cancer-associated, gain-of-function TP53 variant P152Lp53 activates multiple signaling pathways implicated in tumorigenesis Article Snippet: substitution at 152nd amino acid position in p53: To model the location of proline at position 152 of p53, coordinates of the human p53 DNA-binding domain bound to DNA with Immunohistochemistry:Article Title: Activation of Multiple Signalling Pathways by P152Lp53 Mutant Reveals New Gain-of-function Implicating Tumorigenesis Article Snippet: To model the location of proline at position 152 of p53, coordinates of the human p53 DNA-binding domain bound to DNA with Article Title: The cancer-associated, gain-of-function TP53 variant P152Lp53 activates multiple signaling pathways implicated in tumorigenesis Article Snippet: To model the location of proline at position 152 of p53, coordinates of the human p53 DNA-binding domain bound to DNA with Article Title: The cancer-associated, gain-of-function TP53 variant P152Lp53 activates multiple signaling pathways implicated in tumorigenesis Article Snippet: substitution at 152nd amino acid position in p53: To model the location of proline at position 152 of p53, coordinates of the human p53 DNA-binding domain bound to DNA with Sequencing:Article Title: Activation of Multiple Signalling Pathways by P152Lp53 Mutant Reveals New Gain-of-function Implicating Tumorigenesis Article Snippet: To model the location of proline at position 152 of p53, coordinates of the human p53 DNA-binding domain bound to DNA with Article Title: The cancer-associated, gain-of-function TP53 variant P152Lp53 activates multiple signaling pathways implicated in tumorigenesis Article Snippet: To model the location of proline at position 152 of p53, coordinates of the human p53 DNA-binding domain bound to DNA with Article Title: The cancer-associated, gain-of-function TP53 variant P152Lp53 activates multiple signaling pathways implicated in tumorigenesis Article Snippet: substitution at 152nd amino acid position in p53: To model the location of proline at position 152 of p53, coordinates of the human p53 DNA-binding domain bound to DNA with Software:Article Title: Activation of Multiple Signalling Pathways by P152Lp53 Mutant Reveals New Gain-of-function Implicating Tumorigenesis Article Snippet: To model the location of proline at position 152 of p53, coordinates of the human p53 DNA-binding domain bound to DNA with Article Title: The cancer-associated, gain-of-function TP53 variant P152Lp53 activates multiple signaling pathways implicated in tumorigenesis Article Snippet: To model the location of proline at position 152 of p53, coordinates of the human p53 DNA-binding domain bound to DNA with Article Title: The cancer-associated, gain-of-function TP53 variant P152Lp53 activates multiple signaling pathways implicated in tumorigenesis Article Snippet: substitution at 152nd amino acid position in p53: To model the location of proline at position 152 of p53, coordinates of the human p53 DNA-binding domain bound to DNA with Residue:Article Title: Activation of Multiple Signalling Pathways by P152Lp53 Mutant Reveals New Gain-of-function Implicating Tumorigenesis Article Snippet: To model the location of proline at position 152 of p53, coordinates of the human p53 DNA-binding domain bound to DNA with Article Title: The cancer-associated, gain-of-function TP53 variant P152Lp53 activates multiple signaling pathways implicated in tumorigenesis Article Snippet: To model the location of proline at position 152 of p53, coordinates of the human p53 DNA-binding domain bound to DNA with Article Title: The cancer-associated, gain-of-function TP53 variant P152Lp53 activates multiple signaling pathways implicated in tumorigenesis Article Snippet: substitution at 152nd amino acid position in p53: To model the location of proline at position 152 of p53, coordinates of the human p53 DNA-binding domain bound to DNA with |
