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TargetMol nmda antagonist dizocilpine
Heat maps of median changes in coherence for δ, θ, α, and β frequency bands across lead pairs after administration of saline (NaCl), caffeine (CAF), sulpiride (SLP), haloperidol (HAL), <t>dizocilpine</t> (DIZ), galantamine (GAL), tropicamide (TRO), hydroxyzine (HXZ), aminophenylbutyric acid (PHB), phenazepam (PHE), atipamezole (ATI), dexmedetomidine (DEX), and 5-ethyl-5-phenyl-2,4,6(1H,3H,5H)-pyrimidinetrione (PhBT). Initial data were differences between mean frequency band coherence ~20 min after administration and values before administration (~30 min of baseline recording). For each group, 6–10 recordings were made.
Nmda Antagonist Dizocilpine, supplied by TargetMol, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Cell Signaling Technology Inc rabbit anti glun2a
Heat maps of median changes in coherence for δ, θ, α, and β frequency bands across lead pairs after administration of saline (NaCl), caffeine (CAF), sulpiride (SLP), haloperidol (HAL), <t>dizocilpine</t> (DIZ), galantamine (GAL), tropicamide (TRO), hydroxyzine (HXZ), aminophenylbutyric acid (PHB), phenazepam (PHE), atipamezole (ATI), dexmedetomidine (DEX), and 5-ethyl-5-phenyl-2,4,6(1H,3H,5H)-pyrimidinetrione (PhBT). Initial data were differences between mean frequency band coherence ~20 min after administration and values before administration (~30 min of baseline recording). For each group, 6–10 recordings were made.
Rabbit Anti Glun2a, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Tajima Shoji Co Ltd nmda receptors
Heat maps of median changes in coherence for δ, θ, α, and β frequency bands across lead pairs after administration of saline (NaCl), caffeine (CAF), sulpiride (SLP), haloperidol (HAL), <t>dizocilpine</t> (DIZ), galantamine (GAL), tropicamide (TRO), hydroxyzine (HXZ), aminophenylbutyric acid (PHB), phenazepam (PHE), atipamezole (ATI), dexmedetomidine (DEX), and 5-ethyl-5-phenyl-2,4,6(1H,3H,5H)-pyrimidinetrione (PhBT). Initial data were differences between mean frequency band coherence ~20 min after administration and values before administration (~30 min of baseline recording). For each group, 6–10 recordings were made.
Nmda Receptors, supplied by Tajima Shoji Co Ltd, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Alomone Labs nmda receptor antagonist d ap5
Heat maps of median changes in coherence for δ, θ, α, and β frequency bands across lead pairs after administration of saline (NaCl), caffeine (CAF), sulpiride (SLP), haloperidol (HAL), <t>dizocilpine</t> (DIZ), galantamine (GAL), tropicamide (TRO), hydroxyzine (HXZ), aminophenylbutyric acid (PHB), phenazepam (PHE), atipamezole (ATI), dexmedetomidine (DEX), and 5-ethyl-5-phenyl-2,4,6(1H,3H,5H)-pyrimidinetrione (PhBT). Initial data were differences between mean frequency band coherence ~20 min after administration and values before administration (~30 min of baseline recording). For each group, 6–10 recordings were made.
Nmda Receptor Antagonist D Ap5, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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TargetMol nmda
Heat maps of median changes in coherence for δ, θ, α, and β frequency bands across lead pairs after administration of saline (NaCl), caffeine (CAF), sulpiride (SLP), haloperidol (HAL), <t>dizocilpine</t> (DIZ), galantamine (GAL), tropicamide (TRO), hydroxyzine (HXZ), aminophenylbutyric acid (PHB), phenazepam (PHE), atipamezole (ATI), dexmedetomidine (DEX), and 5-ethyl-5-phenyl-2,4,6(1H,3H,5H)-pyrimidinetrione (PhBT). Initial data were differences between mean frequency band coherence ~20 min after administration and values before administration (~30 min of baseline recording). For each group, 6–10 recordings were made.
Nmda, supplied by TargetMol, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Tocris nmda receptors
Heat maps of median changes in coherence for δ, θ, α, and β frequency bands across lead pairs after administration of saline (NaCl), caffeine (CAF), sulpiride (SLP), haloperidol (HAL), <t>dizocilpine</t> (DIZ), galantamine (GAL), tropicamide (TRO), hydroxyzine (HXZ), aminophenylbutyric acid (PHB), phenazepam (PHE), atipamezole (ATI), dexmedetomidine (DEX), and 5-ethyl-5-phenyl-2,4,6(1H,3H,5H)-pyrimidinetrione (PhBT). Initial data were differences between mean frequency band coherence ~20 min after administration and values before administration (~30 min of baseline recording). For each group, 6–10 recordings were made.
Nmda Receptors, supplied by Tocris, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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MedChemExpress nmda receptor mediated epscs
Heat maps of median changes in coherence for δ, θ, α, and β frequency bands across lead pairs after administration of saline (NaCl), caffeine (CAF), sulpiride (SLP), haloperidol (HAL), <t>dizocilpine</t> (DIZ), galantamine (GAL), tropicamide (TRO), hydroxyzine (HXZ), aminophenylbutyric acid (PHB), phenazepam (PHE), atipamezole (ATI), dexmedetomidine (DEX), and 5-ethyl-5-phenyl-2,4,6(1H,3H,5H)-pyrimidinetrione (PhBT). Initial data were differences between mean frequency band coherence ~20 min after administration and values before administration (~30 min of baseline recording). For each group, 6–10 recordings were made.
Nmda Receptor Mediated Epscs, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Dawley Inc postsynaptic nmda receptor activation
Heat maps of median changes in coherence for δ, θ, α, and β frequency bands across lead pairs after administration of saline (NaCl), caffeine (CAF), sulpiride (SLP), haloperidol (HAL), <t>dizocilpine</t> (DIZ), galantamine (GAL), tropicamide (TRO), hydroxyzine (HXZ), aminophenylbutyric acid (PHB), phenazepam (PHE), atipamezole (ATI), dexmedetomidine (DEX), and 5-ethyl-5-phenyl-2,4,6(1H,3H,5H)-pyrimidinetrione (PhBT). Initial data were differences between mean frequency band coherence ~20 min after administration and values before administration (~30 min of baseline recording). For each group, 6–10 recordings were made.
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Heat maps of median changes in coherence for δ, θ, α, and β frequency bands across lead pairs after administration of saline (NaCl), caffeine (CAF), sulpiride (SLP), haloperidol (HAL), dizocilpine (DIZ), galantamine (GAL), tropicamide (TRO), hydroxyzine (HXZ), aminophenylbutyric acid (PHB), phenazepam (PHE), atipamezole (ATI), dexmedetomidine (DEX), and 5-ethyl-5-phenyl-2,4,6(1H,3H,5H)-pyrimidinetrione (PhBT). Initial data were differences between mean frequency band coherence ~20 min after administration and values before administration (~30 min of baseline recording). For each group, 6–10 recordings were made.

Journal: Methods and Protocols

Article Title: Comparison of the Utility of Amplitude–Spectral and Coherence Features of Psychotropic Drugs’ Action on ECoG Signal for Pharmaco-EEG Based Drug Screening in Rats

doi: 10.3390/mps9050123

Figure Lengend Snippet: Heat maps of median changes in coherence for δ, θ, α, and β frequency bands across lead pairs after administration of saline (NaCl), caffeine (CAF), sulpiride (SLP), haloperidol (HAL), dizocilpine (DIZ), galantamine (GAL), tropicamide (TRO), hydroxyzine (HXZ), aminophenylbutyric acid (PHB), phenazepam (PHE), atipamezole (ATI), dexmedetomidine (DEX), and 5-ethyl-5-phenyl-2,4,6(1H,3H,5H)-pyrimidinetrione (PhBT). Initial data were differences between mean frequency band coherence ~20 min after administration and values before administration (~30 min of baseline recording). For each group, 6–10 recordings were made.

Article Snippet: The training set, against which test-set pharmacological effects were classified, comprised previously published matrices of drug effects [ , , , , ]: the NMDA antagonist dizocilpine (Targetmol Chemicals Inc., Wellesley Hills, MA, USA); D2/D3 dopamine antagonists haloperidol (OOO Velpharm, Russia) and sulpiride (AO Organica, Novokuznetsk, Russia); the M-anticholinergic tropicamide (Tocris Bioscience, Bristol, UK); the H1/5-HT2A receptor blocker hydroxyzine (Sigma-Aldrich Chemie GmbH, Taufkirchen, Germany); the acetylcholinesterase inhibitor galantamine (Sopharma AD, Sofia, Bulgaria); the α2-adrenergic agonist dexmedetomidine (Orion Corporation, Espoo, Finland); and GABA-mimetics aminophenylbutyric acid (phenibut) (Tocris Bioscience, Bristol, UK) and bromdihydrochlorophenylbenzodiazepine (phenazepam) (AO Novosibkhimpharm, Novosibirsk, Russia) ( C).

Techniques: Saline