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Veracyte Inc afirma gene expression classifier gec
Afirma Gene Expression Classifier Gec, supplied by Veracyte Inc, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/microarray-based+gene-expression+test/afirma+classifier+expression+gene/10__2147_slash_pgpm__s181520-37-1-6
Average 86 stars, based on 1 article reviews
afirma gene expression classifier gec - by Bioz Stars, 2026-11
86/100 stars

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Article Title: Phase II trial of combination radiation, hormone, and immunotherapy in grade group 5 prostate cancer.
Article Snippet: A Decipher Prostate Cancer Genomic Classifier (Veracyte, South San Francisco, California, USA) was performed on all enrolled patients.

Article Title: IP47-08 PREDICTING RECURRENCE OF NON-MUSCLE INVASIVE BLADDER CANCER WITH SINGLE CELL RESOLUTION SPATIAL PROTEOMIC ANALYSIS
Article Snippet: INTRODUCTION AND OBJECTIVES: High-risk non-muscleinvasive bladder cancer (HR-NMIBC) is associated with substantial progression and recurrence rates.. Some patients with HR-NMIBC will die from their disease, and aggressive tumors could be treated earlier with radical cystectomy (RC).. Previous work revealed higher rates of pathological upstaging at RC for NMIBC with a non-luminal molecular subtype.

Article Title: Development of an extended version of GALEAS bladder: Detection of FGFR3 fusions in urine and associations between genomic alterations and gene expression
Article Snippet: JJD is a paid consultant and ED an employee of Veracyte Inc, makers of the Decipher Bladder Genomic Subtyping Classifier tissue test (USA).

Formalin-fixed Paraffin-Embedded:

Article Title: Development of an extended version of GALEAS bladder: Detection of FGFR3 fusions in urine and associations between genomic alterations and gene expression
Article Snippet: .. RNA was extracted from macrodissected FFPE tissues and genome-wide gene expression analysed using the Decipher Bladder Genomic Subtyping Classifier (GSC) oligonucleotide microarray assay in a CAP/CLIA laboratory (Veracyte, Inc San Diego, CA). .. Data were SCAN normalized and FGFR1-4 gene expression was extracted and signatures of FGFR3 co-expressed genes and lncRNA-based FGFR3 activity generated using locked classifiers available in the GRID bioinformatics platform (v3.1, Veracyte, Inc).

Genome Wide:

Article Title: Development of an extended version of GALEAS bladder: Detection of FGFR3 fusions in urine and associations between genomic alterations and gene expression
Article Snippet: .. RNA was extracted from macrodissected FFPE tissues and genome-wide gene expression analysed using the Decipher Bladder Genomic Subtyping Classifier (GSC) oligonucleotide microarray assay in a CAP/CLIA laboratory (Veracyte, Inc San Diego, CA). .. Data were SCAN normalized and FGFR1-4 gene expression was extracted and signatures of FGFR3 co-expressed genes and lncRNA-based FGFR3 activity generated using locked classifiers available in the GRID bioinformatics platform (v3.1, Veracyte, Inc).

Article Title: The role of HAI-1 in urothelial bladder cancer: Tissue expression, ectodomain shedding and clinical outcomes
Article Snippet: .. Genome-wide gene expression was analysed using the Decipher Bladder Genomic Subtyping Classifier (GSC) oligonucleotide microarray assay in a CAP/CLIA laboratory (Veracyte, Inc San Diego, CA). .. Statistical tests were carried out using GraphPad Prism (v10.5.0).

Gene Expression:

Article Title: Development of an extended version of GALEAS bladder: Detection of FGFR3 fusions in urine and associations between genomic alterations and gene expression
Article Snippet: .. RNA was extracted from macrodissected FFPE tissues and genome-wide gene expression analysed using the Decipher Bladder Genomic Subtyping Classifier (GSC) oligonucleotide microarray assay in a CAP/CLIA laboratory (Veracyte, Inc San Diego, CA). .. Data were SCAN normalized and FGFR1-4 gene expression was extracted and signatures of FGFR3 co-expressed genes and lncRNA-based FGFR3 activity generated using locked classifiers available in the GRID bioinformatics platform (v3.1, Veracyte, Inc).

Article Title: The role of HAI-1 in urothelial bladder cancer: Tissue expression, ectodomain shedding and clinical outcomes
Article Snippet: .. Genome-wide gene expression was analysed using the Decipher Bladder Genomic Subtyping Classifier (GSC) oligonucleotide microarray assay in a CAP/CLIA laboratory (Veracyte, Inc San Diego, CA). .. Statistical tests were carried out using GraphPad Prism (v10.5.0).

Microarray:

Article Title: Development of an extended version of GALEAS bladder: Detection of FGFR3 fusions in urine and associations between genomic alterations and gene expression
Article Snippet: .. RNA was extracted from macrodissected FFPE tissues and genome-wide gene expression analysed using the Decipher Bladder Genomic Subtyping Classifier (GSC) oligonucleotide microarray assay in a CAP/CLIA laboratory (Veracyte, Inc San Diego, CA). .. Data were SCAN normalized and FGFR1-4 gene expression was extracted and signatures of FGFR3 co-expressed genes and lncRNA-based FGFR3 activity generated using locked classifiers available in the GRID bioinformatics platform (v3.1, Veracyte, Inc).

Article Title: The role of HAI-1 in urothelial bladder cancer: Tissue expression, ectodomain shedding and clinical outcomes
Article Snippet: .. Genome-wide gene expression was analysed using the Decipher Bladder Genomic Subtyping Classifier (GSC) oligonucleotide microarray assay in a CAP/CLIA laboratory (Veracyte, Inc San Diego, CA). .. Statistical tests were carried out using GraphPad Prism (v10.5.0).

Diagnostic Assay:

Article Title: Decreased Interobserver Variability in Nuclear Atypia of Undetermined Significance After Consensus Review of Thyroid Fine Needle Aspirations.
Article Snippet: Introduction: The 2023 Bethesda System for Reporting Thyroid Cytopathology (TBS) subcategorizes Atypia of Undetermined Significance (AUS) into two tiers: nuclear atypia and other.. Despite this standardized reporting system, limitations still exist, specifically the low reproducibility of AUS.. We sought to determine if group review can improve interobserver variability with the twotiered AUS before implementation at our institution.

Article Title: Subcentimeter thyroid nodules: Diagnostic challenges, risk stratification and management in contemporary surgical oncology practice.
Article Snippet: Subcentimeter thyroid nodules, defined as those measuring less than 10 mm in maximum diameter, represent a growing diagnostic and surgical oncology challenge.. The proliferation of neck ultrasonography has dramatically increased their incidental detection, yet existing risk stratification systems were validated predominantly in larger nodule cohorts.. This is a narrative review of contemporary evidence, incorporating data from the ElaTION randomised controlled trial, the recent 2026 BTA/BAETS Joint Consensus Statement, and service-level analyses from a single UK centre, to evaluate the diagnostic performance, risk stratification and optimal management of subcentimeter thyroid nodules.

Genomic Sequencing:

Article Title: Decreased Interobserver Variability in Nuclear Atypia of Undetermined Significance After Consensus Review of Thyroid Fine Needle Aspirations.
Article Snippet: Introduction: The 2023 Bethesda System for Reporting Thyroid Cytopathology (TBS) subcategorizes Atypia of Undetermined Significance (AUS) into two tiers: nuclear atypia and other.. Despite this standardized reporting system, limitations still exist, specifically the low reproducibility of AUS.. We sought to determine if group review can improve interobserver variability with the twotiered AUS before implementation at our institution.

Sequencing:

Article Title: Subcentimeter thyroid nodules: Diagnostic challenges, risk stratification and management in contemporary surgical oncology practice.
Article Snippet: Subcentimeter thyroid nodules, defined as those measuring less than 10 mm in maximum diameter, represent a growing diagnostic and surgical oncology challenge.. The proliferation of neck ultrasonography has dramatically increased their incidental detection, yet existing risk stratification systems were validated predominantly in larger nodule cohorts.. This is a narrative review of contemporary evidence, incorporating data from the ElaTION randomised controlled trial, the recent 2026 BTA/BAETS Joint Consensus Statement, and service-level analyses from a single UK centre, to evaluate the diagnostic performance, risk stratification and optimal management of subcentimeter thyroid nodules.



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