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ovarian cancer and normal tissue high density tissue microarray ov208  (Biomax Inc)

 
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    Biomax Inc ovarian cancer and normal tissue high density tissue microarray ov208
    RCC2 was over-expressed in lung cancers and ovarian cancers. a IHC of HeLa cells was performed with anti-RCC2 antibody (D14F3, cell signaling). RCC2 signals were seen in nucleus and midbody of a telophase cell as expected. Cytoplasmic RCC2 was also observed. b RCC2 expression in a lung cancer tissue <t>microarray</t> was evaluated by IHC. RCC2 were not seen in normal lung (left) but highly expressed in lung cancer (10×, scale bar: 100 μm). In addition to nuclei, RCC2 signals were also seen in cytoplasm in some lung cancers ( c ). d RCC2 expression in an ovarian cancer tissue microarray was evaluated by IHC. Normal ovaries expressed none or weak RCC2 (−~+) (left). Increased RCC2 expression was seen in majority of ovarian cancers
    Ovarian Cancer And Normal Tissue High Density Tissue Microarray Ov208, supplied by Biomax Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/high-density+oligonucleotides+microarray+analysis/tissue+microarray+samples+ov208a/pmc05763756-107-14-21
    Average 90 stars, based on 1 article reviews
    ovarian cancer and normal tissue high density tissue microarray ov208 - by Bioz Stars, 2026-11
    90/100 stars

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    1) Product Images from "RCC2 over-expression in tumor cells alters apoptosis and drug sensitivity by regulating Rac1 activation"

    Article Title: RCC2 over-expression in tumor cells alters apoptosis and drug sensitivity by regulating Rac1 activation

    Journal: BMC Cancer

    doi: 10.1186/s12885-017-3908-y

    RCC2 was over-expressed in lung cancers and ovarian cancers. a IHC of HeLa cells was performed with anti-RCC2 antibody (D14F3, cell signaling). RCC2 signals were seen in nucleus and midbody of a telophase cell as expected. Cytoplasmic RCC2 was also observed. b RCC2 expression in a lung cancer tissue microarray was evaluated by IHC. RCC2 were not seen in normal lung (left) but highly expressed in lung cancer (10×, scale bar: 100 μm). In addition to nuclei, RCC2 signals were also seen in cytoplasm in some lung cancers ( c ). d RCC2 expression in an ovarian cancer tissue microarray was evaluated by IHC. Normal ovaries expressed none or weak RCC2 (−~+) (left). Increased RCC2 expression was seen in majority of ovarian cancers
    Figure Legend Snippet: RCC2 was over-expressed in lung cancers and ovarian cancers. a IHC of HeLa cells was performed with anti-RCC2 antibody (D14F3, cell signaling). RCC2 signals were seen in nucleus and midbody of a telophase cell as expected. Cytoplasmic RCC2 was also observed. b RCC2 expression in a lung cancer tissue microarray was evaluated by IHC. RCC2 were not seen in normal lung (left) but highly expressed in lung cancer (10×, scale bar: 100 μm). In addition to nuclei, RCC2 signals were also seen in cytoplasm in some lung cancers ( c ). d RCC2 expression in an ovarian cancer tissue microarray was evaluated by IHC. Normal ovaries expressed none or weak RCC2 (−~+) (left). Increased RCC2 expression was seen in majority of ovarian cancers

    Techniques Used: Expressing, Microarray

    Related Articles

    Microarray:

    Article Title: Decreased expression of ALDH5A1 predicts prognosis in patients with ovarian cancer
    Article Snippet: .. Tissue microarray samples were obtained from the University of Michigan, Biomax (OV208a) and included formalin-fixed paraffin-embedded serous papillary adenocarcinoma (n = 130), mucinous papillary adenocarcinoma(n = 24), adenocarcinoma (n = 7), serous adenocarcinoma (n = 2), disgerminoma (n = 5), endodermal sinus carcinoma(n = 7), endometrioid carcinoma(n = 3), embryonal carcinoma (n = 1), immature teratoma(n = 2), mature teratoma(n = 1), clear cell carcinoma (n = 1), transitional cell carcinoma(n = 1), strumal carcinoid(n = 1), squamous cell carcinoma from teratoma with malignant transformation(n = 3), granular cell tumor(n = 4), normal ovarian epithelial tissue (n = 2), and adjacent normal ovary tissue (n = 14). ..

    Article Title: RCC2 over-expression in tumor cells alters apoptosis and drug sensitivity by regulating Rac1 activation
    Article Snippet: .. Lung carcinoma progression tissue microarray (LC2083; Biomax; Rockville, MD, USA) and ovarian cancer and normal tissue high density tissue microarray (OV208; Biomax) were de-paraffinized in xylene, antigen-retrieved by heating in 0.01 M sodium citrate buffer (pH 6.0) at 95 °C for 10 min, blocked in 10% normal goat serum for 30 min and incubated with an anti-RCC2 antibody (D14F3; Cell Signaling, Danvers, MA, USA) overnight at 4 °C. .. Immunohistochemistry staining was performed using a mouse and rabbit specific HRP/AEC (ABC) detection IHC kit (Abcam Ab93705; Boston, MA, USA).

    Formalin-fixed Paraffin-Embedded:

    Article Title: Decreased expression of ALDH5A1 predicts prognosis in patients with ovarian cancer
    Article Snippet: .. Tissue microarray samples were obtained from the University of Michigan, Biomax (OV208a) and included formalin-fixed paraffin-embedded serous papillary adenocarcinoma (n = 130), mucinous papillary adenocarcinoma(n = 24), adenocarcinoma (n = 7), serous adenocarcinoma (n = 2), disgerminoma (n = 5), endodermal sinus carcinoma(n = 7), endometrioid carcinoma(n = 3), embryonal carcinoma (n = 1), immature teratoma(n = 2), mature teratoma(n = 1), clear cell carcinoma (n = 1), transitional cell carcinoma(n = 1), strumal carcinoid(n = 1), squamous cell carcinoma from teratoma with malignant transformation(n = 3), granular cell tumor(n = 4), normal ovarian epithelial tissue (n = 2), and adjacent normal ovary tissue (n = 14). ..

    Transformation Assay:

    Article Title: Decreased expression of ALDH5A1 predicts prognosis in patients with ovarian cancer
    Article Snippet: .. Tissue microarray samples were obtained from the University of Michigan, Biomax (OV208a) and included formalin-fixed paraffin-embedded serous papillary adenocarcinoma (n = 130), mucinous papillary adenocarcinoma(n = 24), adenocarcinoma (n = 7), serous adenocarcinoma (n = 2), disgerminoma (n = 5), endodermal sinus carcinoma(n = 7), endometrioid carcinoma(n = 3), embryonal carcinoma (n = 1), immature teratoma(n = 2), mature teratoma(n = 1), clear cell carcinoma (n = 1), transitional cell carcinoma(n = 1), strumal carcinoid(n = 1), squamous cell carcinoma from teratoma with malignant transformation(n = 3), granular cell tumor(n = 4), normal ovarian epithelial tissue (n = 2), and adjacent normal ovary tissue (n = 14). ..

    Incubation:

    Article Title: RCC2 over-expression in tumor cells alters apoptosis and drug sensitivity by regulating Rac1 activation
    Article Snippet: .. Lung carcinoma progression tissue microarray (LC2083; Biomax; Rockville, MD, USA) and ovarian cancer and normal tissue high density tissue microarray (OV208; Biomax) were de-paraffinized in xylene, antigen-retrieved by heating in 0.01 M sodium citrate buffer (pH 6.0) at 95 °C for 10 min, blocked in 10% normal goat serum for 30 min and incubated with an anti-RCC2 antibody (D14F3; Cell Signaling, Danvers, MA, USA) overnight at 4 °C. .. Immunohistochemistry staining was performed using a mouse and rabbit specific HRP/AEC (ABC) detection IHC kit (Abcam Ab93705; Boston, MA, USA).



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