gene expression profile (Scherf GmbH)
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Gene Expression Profile, supplied by Scherf GmbH, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/gene+pattern/gene+expression+patterns/pm12226758-36-3-32
Average 90 stars, based on 1 article reviews
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other:Article Title: CHEK2 genomic and proteomic analyses reveal genetic inactivation or endogenous activation across the 60 cell lines of the US National Cancer Institute Article Snippet: The Article Title: Role of cis-regulatory elements on the ring-specific hrp3 promoter in the human parasite Plasmodium falciparum. Article Snippet: Identification of promoter elements responsible for regulation of gene expression has been hampered by the AT richness of P. falciparum intergenic regions.. Nested deletions of histidine-rich protein 3 (hrp3) promoter suggested the presence of a multipartite ring-specific element.. Linker scanning (LS) of this ring-specific promoter showed that the alteration of several promoter regions decreased the luciferase activity compared to the wild-type configuration, indicating that these regions played a role in gene expression. Article Title: Gordon Research Conferences Article Snippet: c conferences, where leading investigators from around the globe discuss their latest work and future challenges in a uniquely informal, interactive format.. Session II 2009 meetings will be held in New England in the United States and internationally in Italy, China, Switzerland, and the United Kingdom.. Apply to a Gordon Research Conference now and see why attendees consistently rate them “the best conference I’ve attended this year”. Article Title: Botulinum toxin type A in multimodal management of age-related macular degeneration and related diseases. Article Snippet: Age related macular degeneration (AMD) is the major cause of visual loss in the aging population in the Western world.. In past decade, intra ocular injections of anti-vascular endothelial growth factor (anti-VEGF) pharmaceuticals have revolutionized therapy for exudative (edematous-wet) AMD and become standard practice for the near term.. However repeated intra-ocular injections are required for years and long terms results have been limited. Gene Expression:Article Title: Gene expression profile of peripheral blood mononuclear cells in response to HIV-VLPs stimulation Article Snippet: .. Ross DT, Scherf U, Eisen MB, Perou CM, Rees C, Spellman PT, Iyer V, Jeffrey SS, Van de Rijn M, Waltham M, Pergamenschikov A, Lee JC, Lashkari D, Shalon D, Myers TG, Weinstein JN, Botstein D, Brown PO: Systematic variation in Article Title: Differential gene expression as a potential classifier of 2-(4-amino-3-methylphenyl)-5-fluorobenzothiazole-sensitive and -insensitive cell lines. Article Snippet: 2-(4-Amino-3-methylphenyl)-5-fluorobenzothiazole (5F-203) is a candidate antitumor agent empirically discovered with the aid of the National Cancer Institute (NCI) Anticancer Drug Screen.. In an effort to determine whether basal expression of genes could be used to classify cell sensitivity to this agent, serial analysis of gene expression (SAGE) libraries were generated for three sensitive and two insensitive human tumor cell lines.. When the SAGE tags expressed within these cell line libraries were compared and evaluated for differences, several genes seemed more highly expressed in 5F-203-sensitive cell lines than in the insensitive cell lines. Article Title: Toxicogenomics and cross-species biomarker discovery: applications in drug discovery and safety assessment. Article Snippet: Toxicogenomics has evolved into a useful technique for providing greater mechanistic insights into adverse effects that will spur the development of novel approaches for identifying and understanding toxicity issues.. The ability to capture a snapshot of the transcriptome at any given time during the development of an adverse phenotype allows unprecedented molecular views into the dynamic physiological changes that are occurring on either time or dose continuum for a toxicology study of interest advancing our basic knowledge of adverse events, and providing the necessary scientific framework for developing new strategies and tools for safety assessment programs.. The development of an effective subset of cost effective devices for identifying toxicity earlier in the drug development process will help identify the most promising candidate compounds to move forward leading to a reduction in compound attrition due to toxicity. Activity Assay:Article Title: Toxicogenomics and cross-species biomarker discovery: applications in drug discovery and safety assessment. Article Snippet: Toxicogenomics has evolved into a useful technique for providing greater mechanistic insights into adverse effects that will spur the development of novel approaches for identifying and understanding toxicity issues.. The ability to capture a snapshot of the transcriptome at any given time during the development of an adverse phenotype allows unprecedented molecular views into the dynamic physiological changes that are occurring on either time or dose continuum for a toxicology study of interest advancing our basic knowledge of adverse events, and providing the necessary scientific framework for developing new strategies and tools for safety assessment programs.. The development of an effective subset of cost effective devices for identifying toxicity earlier in the drug development process will help identify the most promising candidate compounds to move forward leading to a reduction in compound attrition due to toxicity. |
