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GenMark Diagnostics esensor 2c19 test reagents
Esensor 2c19 Test Reagents, supplied by GenMark Diagnostics, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/esensor+system/esensor+2c19+test/pmc03310336-191-39-49
Average 90 stars, based on 1 article reviews
esensor 2c19 test reagents - by Bioz Stars, 2026-09
90/100 stars

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Related Articles

Variant Assay:

Article Title: An allele-specific PCR system for rapid detection and discrimination of the CYP2C19∗4A, ∗4B, and ∗17 alleles: implications for clopidogrel response testing.
Article Snippet: For both cohorts, genomic DNA was isolated with the Puregene DNA Purification kit (Qiagen, Valencia, CA) according to the manufacturer’s instructions. .. 1⁄2F1 1⁄2T1 318 319 320 321 322 323 324 325 326 327 328 329 330 331 332 333 334 335 Genotyping The designations of all CYP2C19 alleles refer to those defined by the Cytochrome P450 Allele Nomenclature Committee (http://www.cypalleles.ki.se/cyp2c19.htm, last accessed September 5, 2013).7 Eleven variant CYP2C19 alleles (*2 to *10, *13, *17) were genotyped with the eSensor 2C19 Test (GenMark Diagnostics, Carlsbad, CA) according to the manufacturer’s instructions and as previously described.12 The wild-type (*1) CYP2C19 allele was assigned in the absence of other detectable variant alleles, and representative positive control samples for the CYP2C19*17 and CYP2C19*4 alleles were confirmed by bidirectional sequencing with the use of Mutation Surveyor software version 4.0 (SoftGenetics, State College, PA). ..

Article Title: Identification of CYP2C19 * 4B : pharmacogenetic implications for drug metabolism including clopidogrel responsiveness
Article Snippet: .. 3 Eleven variant CYP2C19 alleles (* 2 –* 10 , * 13 and * 17 ) were genotyped using the eSensor 2C19 Test (GenMark Diagnostics, Carlsbad, CA, USA) as per the manufacturer’s instructions. ..

Positive Control:

Article Title: An allele-specific PCR system for rapid detection and discrimination of the CYP2C19∗4A, ∗4B, and ∗17 alleles: implications for clopidogrel response testing.
Article Snippet: For both cohorts, genomic DNA was isolated with the Puregene DNA Purification kit (Qiagen, Valencia, CA) according to the manufacturer’s instructions. .. 1⁄2F1 1⁄2T1 318 319 320 321 322 323 324 325 326 327 328 329 330 331 332 333 334 335 Genotyping The designations of all CYP2C19 alleles refer to those defined by the Cytochrome P450 Allele Nomenclature Committee (http://www.cypalleles.ki.se/cyp2c19.htm, last accessed September 5, 2013).7 Eleven variant CYP2C19 alleles (*2 to *10, *13, *17) were genotyped with the eSensor 2C19 Test (GenMark Diagnostics, Carlsbad, CA) according to the manufacturer’s instructions and as previously described.12 The wild-type (*1) CYP2C19 allele was assigned in the absence of other detectable variant alleles, and representative positive control samples for the CYP2C19*17 and CYP2C19*4 alleles were confirmed by bidirectional sequencing with the use of Mutation Surveyor software version 4.0 (SoftGenetics, State College, PA). ..

Sequencing:

Article Title: An allele-specific PCR system for rapid detection and discrimination of the CYP2C19∗4A, ∗4B, and ∗17 alleles: implications for clopidogrel response testing.
Article Snippet: For both cohorts, genomic DNA was isolated with the Puregene DNA Purification kit (Qiagen, Valencia, CA) according to the manufacturer’s instructions. .. 1⁄2F1 1⁄2T1 318 319 320 321 322 323 324 325 326 327 328 329 330 331 332 333 334 335 Genotyping The designations of all CYP2C19 alleles refer to those defined by the Cytochrome P450 Allele Nomenclature Committee (http://www.cypalleles.ki.se/cyp2c19.htm, last accessed September 5, 2013).7 Eleven variant CYP2C19 alleles (*2 to *10, *13, *17) were genotyped with the eSensor 2C19 Test (GenMark Diagnostics, Carlsbad, CA) according to the manufacturer’s instructions and as previously described.12 The wild-type (*1) CYP2C19 allele was assigned in the absence of other detectable variant alleles, and representative positive control samples for the CYP2C19*17 and CYP2C19*4 alleles were confirmed by bidirectional sequencing with the use of Mutation Surveyor software version 4.0 (SoftGenetics, State College, PA). ..

Mutagenesis:

Article Title: An allele-specific PCR system for rapid detection and discrimination of the CYP2C19∗4A, ∗4B, and ∗17 alleles: implications for clopidogrel response testing.
Article Snippet: For both cohorts, genomic DNA was isolated with the Puregene DNA Purification kit (Qiagen, Valencia, CA) according to the manufacturer’s instructions. .. 1⁄2F1 1⁄2T1 318 319 320 321 322 323 324 325 326 327 328 329 330 331 332 333 334 335 Genotyping The designations of all CYP2C19 alleles refer to those defined by the Cytochrome P450 Allele Nomenclature Committee (http://www.cypalleles.ki.se/cyp2c19.htm, last accessed September 5, 2013).7 Eleven variant CYP2C19 alleles (*2 to *10, *13, *17) were genotyped with the eSensor 2C19 Test (GenMark Diagnostics, Carlsbad, CA) according to the manufacturer’s instructions and as previously described.12 The wild-type (*1) CYP2C19 allele was assigned in the absence of other detectable variant alleles, and representative positive control samples for the CYP2C19*17 and CYP2C19*4 alleles were confirmed by bidirectional sequencing with the use of Mutation Surveyor software version 4.0 (SoftGenetics, State College, PA). ..

Software:

Article Title: An allele-specific PCR system for rapid detection and discrimination of the CYP2C19∗4A, ∗4B, and ∗17 alleles: implications for clopidogrel response testing.
Article Snippet: For both cohorts, genomic DNA was isolated with the Puregene DNA Purification kit (Qiagen, Valencia, CA) according to the manufacturer’s instructions. .. 1⁄2F1 1⁄2T1 318 319 320 321 322 323 324 325 326 327 328 329 330 331 332 333 334 335 Genotyping The designations of all CYP2C19 alleles refer to those defined by the Cytochrome P450 Allele Nomenclature Committee (http://www.cypalleles.ki.se/cyp2c19.htm, last accessed September 5, 2013).7 Eleven variant CYP2C19 alleles (*2 to *10, *13, *17) were genotyped with the eSensor 2C19 Test (GenMark Diagnostics, Carlsbad, CA) according to the manufacturer’s instructions and as previously described.12 The wild-type (*1) CYP2C19 allele was assigned in the absence of other detectable variant alleles, and representative positive control samples for the CYP2C19*17 and CYP2C19*4 alleles were confirmed by bidirectional sequencing with the use of Mutation Surveyor software version 4.0 (SoftGenetics, State College, PA). ..

other:

Article Title: Identification of CYP2C19 * 4B : pharmacogenetic implications for drug metabolism including clopidogrel responsiveness
Article Snippet: This research was supported in part by a research training grant (5 T32 GM082773) and a grant (UL1RR029887) for the Mount Sinai Institutes for Clinical and Translational Sciences from the National Center for Research Resources, National Institutes of Health. eSensor 2C19 Test reagents for this study were supplied by GenMark Diagnostics (Carlsbad, CA, USA).

Article Title: Exome Sequencing of Extreme Clopidogrel Response Phenotypes Identifies B4GALT2 as a Determinant of On-treatment Platelet Reactivity
Article Snippet: For the replication cohort (see below), 11 CYP2C19 alleles (* 2 - * 10 , * 13 , * 17 ) were genotyped using the eSensor® 2C19 Test (GenMark Diagnostics, Carlsbad, CA, USA) as per the manufacturer's instructions.

Article Title: Multi-ethnic Distribution of Clinically Relevant CYP2C Genotypes and Haplotypes
Article Snippet: Eleven variant CYP2C19 alleles (* 2 – * 10 , * , * 17 ) were genotyped using the eSensor® 2C19 Test (GenMark Diagnostics, Carlsbad, CA) as per the manufacturer's instructions, and five additional variant CYP2C19 alleles (* 12 , * 14 – * , * 22 ) and ABCB1 c.3435C>T were genotyped using a custom multiplexed SNaPshot® single base extension assay (Applied Biosystems, Carlsbad, CA) as previously described.



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Evidence for the role of HRV in adults with symptoms of lower respiratory infection from studies with matched controls

Journal: Respiratory Research

Article Title: Hidden in plain sight: the impact of human rhinovirus infection in adults

doi: 10.1186/s12931-025-03178-w

Figure Lengend Snippet: Evidence for the role of HRV in adults with symptoms of lower respiratory infection from studies with matched controls

Article Snippet: GenMark Dx eSensor RVP , HRV only , 89.2 , 96.1 , Reports HRV-specific detection Lower sensitivity.

Techniques: Infection, Virus, Control

Comparison of Commercial Multiplex PCR Assays for Detection of Human Rhinoviruses (HRVs) and Enteroviruses (EVs)

Journal: Respiratory Research

Article Title: Hidden in plain sight: the impact of human rhinovirus infection in adults

doi: 10.1186/s12931-025-03178-w

Figure Lengend Snippet: Comparison of Commercial Multiplex PCR Assays for Detection of Human Rhinoviruses (HRVs) and Enteroviruses (EVs)

Article Snippet: GenMark Dx eSensor RVP , HRV only , 89.2 , 96.1 , Reports HRV-specific detection Lower sensitivity.

Techniques: Comparison, Multiplex Assay, Luminex