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fluorescence module  (Nikon)


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    Structured Review

    Nikon fluorescence module
    Fluorescence Module, supplied by Nikon, used in various techniques. Bioz Stars score: 95/100, based on 311 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/eclipse+ts2-fl/Maximum+Magnification+Module/pm38890499-120-36-39
    Average 95 stars, based on 311 article reviews
    fluorescence module - by Bioz Stars, 2026-11
    95/100 stars

    Images

    Related Articles

    Microscopy:

    Article Title: Methods for multiplex imaging using labeled nucleic acid imaging agents
    Article Snippet: .. Samples were loaded onto an inverted Nikon Eclipse Ti microscope (Nikon Instruments) with a fluorescence module and an Andor Zyla sCMOS camera. ..

    Article Title: Methods for multiplex imaging using labeled nucleic acid imaging agents
    Article Snippet: .. Samples were imaged using an inverted Nikon Eclipse Ti microscope (Nikon Instruments) with a fluorescence module and an Andor Zyla sCMOS camera. ..

    Article Title: Enhancing Lateral Resolution Using Two-Colour Direct Stochastic Optical Reconstruction Microscopy to Unravel Synaptic Tau Pathology in Alzheimer's Disease.
    Article Snippet: Aims: In Alzheimer's disease (AD), the pathological accumulation of tau in synapses contributes to synapse dysfunction and loss.. However, the small and complex structure of synapses limits the investigation when using conventional techniques.. In this work, we describe the combination of array tomography (AT) with twocolour direct stochastic optical reconstruction microscopy (dSTORM) to enhance lateral resolution for resolving synaptic terminals in human postmortem brain.

    Fluorescence:

    Article Title: Methods for multiplex imaging using labeled nucleic acid imaging agents
    Article Snippet: .. Samples were loaded onto an inverted Nikon Eclipse Ti microscope (Nikon Instruments) with a fluorescence module and an Andor Zyla sCMOS camera. ..

    Article Title: Methods for multiplex imaging using labeled nucleic acid imaging agents
    Article Snippet: .. Samples were imaged using an inverted Nikon Eclipse Ti microscope (Nikon Instruments) with a fluorescence module and an Andor Zyla sCMOS camera. ..

    Software:

    Article Title: Amylin exacerbates tau pathology in the visual cortex of diabetic mice by impairing lysosomal activity
    Article Snippet: .. High-magnification z-stack images 265 were converted to maximum intensity 2D projections and deconvolved in NIS-Elements 266 software (Nikon) 52. ..

    Article Title: Enhancing Lateral Resolution Using Two-Colour Direct Stochastic Optical Reconstruction Microscopy to Unravel Synaptic Tau Pathology in Alzheimer's Disease.
    Article Snippet: Aims: In Alzheimer's disease (AD), the pathological accumulation of tau in synapses contributes to synapse dysfunction and loss.. However, the small and complex structure of synapses limits the investigation when using conventional techniques.. In this work, we describe the combination of array tomography (AT) with twocolour direct stochastic optical reconstruction microscopy (dSTORM) to enhance lateral resolution for resolving synaptic terminals in human postmortem brain.

    other:

    Article Title: Synergistic Effects of Polycationic and Polyfluorinated Functionalities for Efficient Intracellular Protein Delivery.
    Article Snippet: Intracellular protein therapy is a promising strategy in biologics, including vaccine development, gene editing, and cancer therapeutics.. However, protein-based drug delivery remains a significant challenge, particularly in penetrating cell barriers to reach intracellular targets.. Inspired by transport adjuvants, we designed a series of polymeric vectors to achieve efficient functional protein trafficking with low cytotoxicity.

    Imaging:

    Article Title: Enhancing Lateral Resolution Using Two-Colour Direct Stochastic Optical Reconstruction Microscopy to Unravel Synaptic Tau Pathology in Alzheimer's Disease.
    Article Snippet: Aims: In Alzheimer's disease (AD), the pathological accumulation of tau in synapses contributes to synapse dysfunction and loss.. However, the small and complex structure of synapses limits the investigation when using conventional techniques.. In this work, we describe the combination of array tomography (AT) with twocolour direct stochastic optical reconstruction microscopy (dSTORM) to enhance lateral resolution for resolving synaptic terminals in human postmortem brain.

    Immunofluorescence:

    Article Title: Enhancing Lateral Resolution Using Two-Colour Direct Stochastic Optical Reconstruction Microscopy to Unravel Synaptic Tau Pathology in Alzheimer's Disease.
    Article Snippet: Aims: In Alzheimer's disease (AD), the pathological accumulation of tau in synapses contributes to synapse dysfunction and loss.. However, the small and complex structure of synapses limits the investigation when using conventional techniques.. In this work, we describe the combination of array tomography (AT) with twocolour direct stochastic optical reconstruction microscopy (dSTORM) to enhance lateral resolution for resolving synaptic terminals in human postmortem brain.

    Activation Assay:

    Article Title: Enhancing Lateral Resolution Using Two-Colour Direct Stochastic Optical Reconstruction Microscopy to Unravel Synaptic Tau Pathology in Alzheimer's Disease.
    Article Snippet: Aims: In Alzheimer's disease (AD), the pathological accumulation of tau in synapses contributes to synapse dysfunction and loss.. However, the small and complex structure of synapses limits the investigation when using conventional techniques.. In this work, we describe the combination of array tomography (AT) with twocolour direct stochastic optical reconstruction microscopy (dSTORM) to enhance lateral resolution for resolving synaptic terminals in human postmortem brain.



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    Nikon eclipse ts2 fl microscope
    KY-05009 impairs platelet tethering to immobilized fibrinogen. Adhesion of (A) vehicle (0.5% v/v dimethylsulfoxide [DMSO]) or (B) KY-05009 (10 μM)-treated platelets (4 × 10 7 cells/mL) to fibrinogen (100 μg/mL). F-actin was stained with Alexa Fluor 568 phalloidin (1:100 dilution). Platelets were visualized with a Nikon Eclipse <t>Ts2</t> Fl <t>microscope</t> using a 40X/0.65 objective. Representative images are shown: (C) percentage platelet coverage and (D) mean data; n = 4. Data are presented as mean ± SEM. Data analyzed by 1-way ANOVA; ∗ P < .03.
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    Image Search Results


    KY-05009 impairs platelet tethering to immobilized fibrinogen. Adhesion of (A) vehicle (0.5% v/v dimethylsulfoxide [DMSO]) or (B) KY-05009 (10 μM)-treated platelets (4 × 10 7 cells/mL) to fibrinogen (100 μg/mL). F-actin was stained with Alexa Fluor 568 phalloidin (1:100 dilution). Platelets were visualized with a Nikon Eclipse Ts2 Fl microscope using a 40X/0.65 objective. Representative images are shown: (C) percentage platelet coverage and (D) mean data; n = 4. Data are presented as mean ± SEM. Data analyzed by 1-way ANOVA; ∗ P < .03.

    Journal: Research and Practice in Thrombosis and Haemostasis

    Article Title: TRAF2 and NCK interacting kinase: a novel regulator of integrin α IIb β 3 signaling in platelets

    doi: 10.1016/j.rpth.2025.103204

    Figure Lengend Snippet: KY-05009 impairs platelet tethering to immobilized fibrinogen. Adhesion of (A) vehicle (0.5% v/v dimethylsulfoxide [DMSO]) or (B) KY-05009 (10 μM)-treated platelets (4 × 10 7 cells/mL) to fibrinogen (100 μg/mL). F-actin was stained with Alexa Fluor 568 phalloidin (1:100 dilution). Platelets were visualized with a Nikon Eclipse Ts2 Fl microscope using a 40X/0.65 objective. Representative images are shown: (C) percentage platelet coverage and (D) mean data; n = 4. Data are presented as mean ± SEM. Data analyzed by 1-way ANOVA; ∗ P < .03.

    Article Snippet: Representative images were taken using a Nikon Eclipse Ts2 Fl microscope with a 40X/0.65 objective.

    Techniques: Staining, Microscopy

    KY-05009 treatment attenuates thrombus formation under arterial shear stress. DIOC6 labeled whole blood was treated with (A) vehicle (DMSO, 1% v/v), (B) KY-05009 (10 μM), (C) KY-05009 (50 μM), or (D) KY-05009 (100 μM) and perfused over collagen coated (100μg/mL) Vena8 Fluoro+ Biochips using a Cellix perfusion system at arterial sheer stress (20 dynes/cm 2 ) for 10 minutes. Thrombus formation was determined by monitoring the change in fluorescence intensity observed over recorded intervals. Representative images were taken using a Nikon Eclipse Ts2 Fl microscope with a 40X/0.65 objective. The fluorescence intensity of the formed thrombi were normalized to the maximum fluorescence intensity value of the vehicle after 10 minutes and expressed as a percentage; n = 6. Decimated averages at each time point are presented ± SEM. (E) Annexin V binding to platelets treated with vehicle (DMSO, 1% v/v) or KY-005009 (10-100 μM). Platelets were gated and 10 000 events were recorded. Mean ± SEM of raw median fluorescence intensity data are presented; n = 3. Thrombus formation data analyzed by 2-way ANOVA; flow cytometry data analyzed by 1-way ANOVA; ∗ P < .03.

    Journal: Research and Practice in Thrombosis and Haemostasis

    Article Title: TRAF2 and NCK interacting kinase: a novel regulator of integrin α IIb β 3 signaling in platelets

    doi: 10.1016/j.rpth.2025.103204

    Figure Lengend Snippet: KY-05009 treatment attenuates thrombus formation under arterial shear stress. DIOC6 labeled whole blood was treated with (A) vehicle (DMSO, 1% v/v), (B) KY-05009 (10 μM), (C) KY-05009 (50 μM), or (D) KY-05009 (100 μM) and perfused over collagen coated (100μg/mL) Vena8 Fluoro+ Biochips using a Cellix perfusion system at arterial sheer stress (20 dynes/cm 2 ) for 10 minutes. Thrombus formation was determined by monitoring the change in fluorescence intensity observed over recorded intervals. Representative images were taken using a Nikon Eclipse Ts2 Fl microscope with a 40X/0.65 objective. The fluorescence intensity of the formed thrombi were normalized to the maximum fluorescence intensity value of the vehicle after 10 minutes and expressed as a percentage; n = 6. Decimated averages at each time point are presented ± SEM. (E) Annexin V binding to platelets treated with vehicle (DMSO, 1% v/v) or KY-005009 (10-100 μM). Platelets were gated and 10 000 events were recorded. Mean ± SEM of raw median fluorescence intensity data are presented; n = 3. Thrombus formation data analyzed by 2-way ANOVA; flow cytometry data analyzed by 1-way ANOVA; ∗ P < .03.

    Article Snippet: Representative images were taken using a Nikon Eclipse Ts2 Fl microscope with a 40X/0.65 objective.

    Techniques: Shear, Labeling, Fluorescence, Microscopy, Binding Assay, Flow Cytometry