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BioSolveIT GmbH flexx docking algorithm
TABLE 1
Flexx Docking Algorithm, supplied by BioSolveIT GmbH, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/docking+software+biosolveit%E2%80%99s+flexx+program/flexx+docking+algorithm/pmc03401010-54-2-5
Average 90 stars, based on 1 article reviews
flexx docking algorithm - by Bioz Stars, 2026-09
90/100 stars

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1) Product Images from "Identification and Validation of Novel Human Pregnane X Receptor Activators among Prescribed Drugs via Ligand-Based Virtual Screening "

Article Title: Identification and Validation of Novel Human Pregnane X Receptor Activators among Prescribed Drugs via Ligand-Based Virtual Screening

Journal: Drug Metabolism and Disposition

doi: 10.1124/dmd.110.035808

TABLE 1
Figure Legend Snippet: TABLE 1

Techniques Used: Biomarker Discovery

Related Articles

Software:

Article Title: Spiro-acridine inhibiting tyrosinase enzyme: Kinetic, protein-ligand interaction and molecular docking studies.
Article Snippet: AC C EP TE D M AN U SC R Here, we evaluate spiro-acridines as inhibitors of tyrosinase, a key enzyme to melanogenesis.. For this purpose, the spiro-acridines 3-(acridin-9-yl)-N-benzylidene-2-cyanoacrylohydrazide (AMTAC-01) and 3-(acridin-9-yl)-2-cyano-N-(4-metoxybenzylidene)-acrylohydrazide (AMTAC-02) were synthesized and their enzymatic inhibition types and mechanisms were investigated.. In addition, the interaction of these compounds with the enzyme were studied by UV-vis spectroscopy, spectrofluorimetry, 1 H NMR titration as well as molecular docking.

Article Title: Computer-aided Discovery of a New Nav1.7 Inhibitor for Treatment of Pain and Itch
Article Snippet: .. Binding positions of each ligand retrieved from the similarity search were generated, scored for predicted binding affinity, and ranked using the FlexX algorithm (LeadIT software package version 2.3.2, BioSolveIT GmbH, Germany). ..

Article Title: Repurposing of FDA-Approved NSAIDs for DPP-4 Inhibition as an Alternative for Diabetes Mellitus Treatment: Computational and in Vitro Study
Article Snippet: .. For this purpose, FDA-approved NSAIDs were chosen to do docking simulations using the FlexX docking algorithm [ ] provided by LeadIT software package version 2.3.2 (BioSolveIT GmbH, Sankt Augustin, Germany). ..

Binding Assay:

Article Title: Spiro-acridine inhibiting tyrosinase enzyme: Kinetic, protein-ligand interaction and molecular docking studies.
Article Snippet: AC C EP TE D M AN U SC R Here, we evaluate spiro-acridines as inhibitors of tyrosinase, a key enzyme to melanogenesis.. For this purpose, the spiro-acridines 3-(acridin-9-yl)-N-benzylidene-2-cyanoacrylohydrazide (AMTAC-01) and 3-(acridin-9-yl)-2-cyano-N-(4-metoxybenzylidene)-acrylohydrazide (AMTAC-02) were synthesized and their enzymatic inhibition types and mechanisms were investigated.. In addition, the interaction of these compounds with the enzyme were studied by UV-vis spectroscopy, spectrofluorimetry, 1 H NMR titration as well as molecular docking.

Article Title: Computer-aided Discovery of a New Nav1.7 Inhibitor for Treatment of Pain and Itch
Article Snippet: .. Binding positions of each ligand retrieved from the similarity search were generated, scored for predicted binding affinity, and ranked using the FlexX algorithm (LeadIT software package version 2.3.2, BioSolveIT GmbH, Germany). ..

Generated:

Article Title: Computer-aided Discovery of a New Nav1.7 Inhibitor for Treatment of Pain and Itch
Article Snippet: .. Binding positions of each ligand retrieved from the similarity search were generated, scored for predicted binding affinity, and ranked using the FlexX algorithm (LeadIT software package version 2.3.2, BioSolveIT GmbH, Germany). ..

other:

Article Title: Over View on Molecular Docking: A Powerful Approach for Structure Based Drug Discovery
Article Snippet: Flex X Algorithm – Incremental reconstruction Scoring Term – Modified Bohm scoring function Advantages – Provides large number of conformations Organization – BioSolveIT Docking Speed – Fast Accuracy of Docking – 75% Availability – Commercial Website – https://www.biosolveit.de/FlexX/ 59 8.



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BioSolveIT GmbH docking software biosolveit’s flexx program
Docking Software Biosolveit’s Flexx Program, supplied by BioSolveIT GmbH, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/docking+software+biosolveit%E2%80%99s+flexx+program/flexx+version+2+0+2+linux64/pm30836241-78-41-40
Average 90 stars, based on 1 article reviews
docking software biosolveit’s flexx program - by Bioz Stars, 2026-09
90/100 stars
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