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Illustrative image of melanoma evolution from an epigenetic point of view, highlighting the aberrant DNA methylation events occurring during the malignization of melanocytes. TSGs, tumor suppressor genes.

Journal: Annals of Translational Medicine

Article Title: Epigenetic mechanisms involved in melanoma pathogenesis and chemoresistance

doi: 10.3978/j.issn.2305-5839.2015.06.20

Figure Lengend Snippet: Illustrative image of melanoma evolution from an epigenetic point of view, highlighting the aberrant DNA methylation events occurring during the malignization of melanocytes. TSGs, tumor suppressor genes.

Article Snippet: Interestingly, Moran et al . demonstrated the suitability of Infinium 450K DNA methylation microarray platform to analyze DNA samples coming from FFPE tissue, obtaining similar results as comparing with frozen tissue counterparts ( 62 ).

Techniques: DNA Methylation Assay