kv1 5 Search Results


kv1 5  (Alomone Labs)
93
Alomone Labs kv1 5
Kv1 5, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 93 stars, based on 1 article reviews
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compound 4  (TargetMol)
93
TargetMol compound 4
Interactions between <t>compound</t> <t>4</t> with ATX enzyme. The compound 4 formed four π-π and one sigma-π interactions with ATX enzyme.
Compound 4, supplied by TargetMol, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/compound 4/product/TargetMol
Average 93 stars, based on 1 article reviews
compound 4 - by Bioz Stars, 2026-04
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kv1 5 antibody  (Santa Cruz Biotechnology)
93
Santa Cruz Biotechnology kv1 5 antibody
Interactions between <t>compound</t> <t>4</t> with ATX enzyme. The compound 4 formed four π-π and one sigma-π interactions with ATX enzyme.
Kv1 5 Antibody, supplied by Santa Cruz Biotechnology, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/kv1 5 antibody/product/Santa Cruz Biotechnology
Average 93 stars, based on 1 article reviews
kv1 5 antibody - by Bioz Stars, 2026-04
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swine  (Alomone Labs)
93
Alomone Labs swine
Interactions between <t>compound</t> <t>4</t> with ATX enzyme. The compound 4 formed four π-π and one sigma-π interactions with ATX enzyme.
Swine, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 93 stars, based on 1 article reviews
swine - by Bioz Stars, 2026-04
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kv1 5 shrna human ltv particles  (Santa Cruz Biotechnology)
85
Santa Cruz Biotechnology kv1 5 shrna human ltv particles
Interactions between <t>compound</t> <t>4</t> with ATX enzyme. The compound 4 formed four π-π and one sigma-π interactions with ATX enzyme.
Kv1 5 Shrna Human Ltv Particles, supplied by Santa Cruz Biotechnology, used in various techniques. Bioz Stars score: 85/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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kv1.5 experiments  (AstraZeneca ltd)
90
AstraZeneca ltd kv1.5 experiments
Interactions between <t>compound</t> <t>4</t> with ATX enzyme. The compound 4 formed four π-π and one sigma-π interactions with ATX enzyme.
Kv1.5 Experiments, supplied by AstraZeneca ltd, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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kv1.5 currents  (IDrug GmbH)
90
IDrug GmbH kv1.5 currents
Interactions between <t>compound</t> <t>4</t> with ATX enzyme. The compound 4 formed four π-π and one sigma-π interactions with ATX enzyme.
Kv1.5 Currents, supplied by IDrug GmbH, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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kv1.5  (ImmunoWay Biotechnology Company)
90
ImmunoWay Biotechnology Company kv1.5
(A) Western blot bands showing p-CaMKII together with p-RyR2. (B) and (C) The relative p-CaMKII and p-RyR2 protein expression. (D) Western blot bands of <t>Kv1.5,</t> Kir3.1 and Kir3.4. (E-G) The relative levels of Kv1.5, Kir3.1 and Kir3.4 proteins; (n = 3). *P < 0.05, **P < 0.01, ***P < 0.001 versus Con group; #P < 0.05, ##P < 0.01, ###P < 0.001, versus AngII group.
Kv1.5, supplied by ImmunoWay Biotechnology Company, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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kv1.5-specific blocker dmm  (Cardiome Inc)
90
Cardiome Inc kv1.5-specific blocker dmm
(A) Western blot bands showing p-CaMKII together with p-RyR2. (B) and (C) The relative p-CaMKII and p-RyR2 protein expression. (D) Western blot bands of <t>Kv1.5,</t> Kir3.1 and Kir3.4. (E-G) The relative levels of Kv1.5, Kir3.1 and Kir3.4 proteins; (n = 3). *P < 0.05, **P < 0.01, ***P < 0.001 versus Con group; #P < 0.05, ##P < 0.01, ###P < 0.001, versus AngII group.
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Image Search Results


Interactions between compound 4 with ATX enzyme. The compound 4 formed four π-π and one sigma-π interactions with ATX enzyme.

Journal: Scientific Reports

Article Title: Design and bioactivity evaluation of a novel autotaxin inhibitor with anti-hepatic fibrosis effects

doi: 10.1038/s41598-025-95464-2

Figure Lengend Snippet: Interactions between compound 4 with ATX enzyme. The compound 4 formed four π-π and one sigma-π interactions with ATX enzyme.

Article Snippet: Compound 4 was purchased from specs through TopScience Co., Ltd for in vitro experiments.

Techniques:

Effects of the compound 4 on liver fibrosis in vivo. Liver sections stained with Sirius red. ( A ) The normal control group. ( B ) Model group. Mice were injected intraperitoneally with 20% CCl4 in rapeseed oil (0.5 ml/100 g body weight, twice weekly) for 33 days. ( C – E ) Model mice were intraperitoneally injected with the compound 4 of low-dose group (7.5 mg/kg), middle-dose (15 mg/kg), high-dose (30 mg/kg), respectively, starting from the 14th day of the CCl4 injection for a total of 20 days. ( F ) The normal mice treated with compound 4 of high-doze group (30 mg/kg) administration. Six random microscope fields were assessed. Magnification×10.

Journal: Scientific Reports

Article Title: Design and bioactivity evaluation of a novel autotaxin inhibitor with anti-hepatic fibrosis effects

doi: 10.1038/s41598-025-95464-2

Figure Lengend Snippet: Effects of the compound 4 on liver fibrosis in vivo. Liver sections stained with Sirius red. ( A ) The normal control group. ( B ) Model group. Mice were injected intraperitoneally with 20% CCl4 in rapeseed oil (0.5 ml/100 g body weight, twice weekly) for 33 days. ( C – E ) Model mice were intraperitoneally injected with the compound 4 of low-dose group (7.5 mg/kg), middle-dose (15 mg/kg), high-dose (30 mg/kg), respectively, starting from the 14th day of the CCl4 injection for a total of 20 days. ( F ) The normal mice treated with compound 4 of high-doze group (30 mg/kg) administration. Six random microscope fields were assessed. Magnification×10.

Article Snippet: Compound 4 was purchased from specs through TopScience Co., Ltd for in vitro experiments.

Techniques: In Vivo, Staining, Control, Injection, Microscopy

Compound 4 inhibits inflammation of liver and effects on blood glucose, blood lipid and renal function in vivo.

Journal: Scientific Reports

Article Title: Design and bioactivity evaluation of a novel autotaxin inhibitor with anti-hepatic fibrosis effects

doi: 10.1038/s41598-025-95464-2

Figure Lengend Snippet: Compound 4 inhibits inflammation of liver and effects on blood glucose, blood lipid and renal function in vivo.

Article Snippet: Compound 4 was purchased from specs through TopScience Co., Ltd for in vitro experiments.

Techniques: Control

(A) Western blot bands showing p-CaMKII together with p-RyR2. (B) and (C) The relative p-CaMKII and p-RyR2 protein expression. (D) Western blot bands of Kv1.5, Kir3.1 and Kir3.4. (E-G) The relative levels of Kv1.5, Kir3.1 and Kir3.4 proteins; (n = 3). *P < 0.05, **P < 0.01, ***P < 0.001 versus Con group; #P < 0.05, ##P < 0.01, ###P < 0.001, versus AngII group.

Journal: PLOS ONE

Article Title: Hydrogen decreases susceptibility to AngII-induced atrial fibrillation and atrial fibrosis via the NOX4/ROS/NLRP3 and TGF-β1/Smad2/3 signaling pathways

doi: 10.1371/journal.pone.0310852

Figure Lengend Snippet: (A) Western blot bands showing p-CaMKII together with p-RyR2. (B) and (C) The relative p-CaMKII and p-RyR2 protein expression. (D) Western blot bands of Kv1.5, Kir3.1 and Kir3.4. (E-G) The relative levels of Kv1.5, Kir3.1 and Kir3.4 proteins; (n = 3). *P < 0.05, **P < 0.01, ***P < 0.001 versus Con group; #P < 0.05, ##P < 0.01, ###P < 0.001, versus AngII group.

Article Snippet: Thereafter, primary antibodies, which included NOX4 (14347-1-AP, Proteintech, 1:1000), p22phox (sc-271968, Santa Cruz Biotechnology, 1:200), NLRP3 (ab214185, Abcam, 1:1000), ASC (sc-514414, Santa Cruz Biotechnology, 1:200), caspase1-p20 (22915–1-AP, Santa Cruz Biotechnology, 1:1,000), phospho-CaMKII (ab182674, Abcam, 1:1000), phospho-RyR2 (Ser2814,GTX00626, Genetex, 1:1000), Kv1.5 (YT2507, ImmunoWay, 1:1000), Kir3.1 (YT2475, ImmunoWay, 1:1000), Kir3.4 (YT2475, ImmunoWay, 1:1000), TGF-β1 (ab215715, Abcam, 1:1000), phospho-TGFβR I (YP1191, ImmunoWay; 1:1000), phospho-TGFβR II (A1415, Abclonal, 1:1000), phospho-Smad2 (YP1185, ImmunoWay; 1:1000), phospho-Smad3 (YP0585, ImmunoWay; 1:1000), α-SMA (bs-10196R, Bioss, 1:1000), collagen I (bs-0578R, Bioss, 1:500), collagen III (bs-0549R,Bioss, 1:500), and GAPDH (10494-1-AP, Proteintech, 1:10000), were added for overnight membrane incubation under 4°C in the shaker.

Techniques: Western Blot, Expressing

(A) ROS production in HL-1 cells by immunofluorescence staining (×200). (B) Expression of NLRP3 within HL-1 cells by immunofluorescence staining (×200). (C) Intracellular Ca 2+ concentration in HL cells by fluorescent probes (×200). (D), (E) and (F) mRNAs of Kv1.5, Kir3.1 and Kir3.4 by qRT-PCR. (n = 3). * P < 0.05, ** P < 0.01, *** P < 0.001, versus Con group; # P < 0.05, ## P < 0.01, ### P < 0.001, versus AngII group.

Journal: PLOS ONE

Article Title: Hydrogen decreases susceptibility to AngII-induced atrial fibrillation and atrial fibrosis via the NOX4/ROS/NLRP3 and TGF-β1/Smad2/3 signaling pathways

doi: 10.1371/journal.pone.0310852

Figure Lengend Snippet: (A) ROS production in HL-1 cells by immunofluorescence staining (×200). (B) Expression of NLRP3 within HL-1 cells by immunofluorescence staining (×200). (C) Intracellular Ca 2+ concentration in HL cells by fluorescent probes (×200). (D), (E) and (F) mRNAs of Kv1.5, Kir3.1 and Kir3.4 by qRT-PCR. (n = 3). * P < 0.05, ** P < 0.01, *** P < 0.001, versus Con group; # P < 0.05, ## P < 0.01, ### P < 0.001, versus AngII group.

Article Snippet: Thereafter, primary antibodies, which included NOX4 (14347-1-AP, Proteintech, 1:1000), p22phox (sc-271968, Santa Cruz Biotechnology, 1:200), NLRP3 (ab214185, Abcam, 1:1000), ASC (sc-514414, Santa Cruz Biotechnology, 1:200), caspase1-p20 (22915–1-AP, Santa Cruz Biotechnology, 1:1,000), phospho-CaMKII (ab182674, Abcam, 1:1000), phospho-RyR2 (Ser2814,GTX00626, Genetex, 1:1000), Kv1.5 (YT2507, ImmunoWay, 1:1000), Kir3.1 (YT2475, ImmunoWay, 1:1000), Kir3.4 (YT2475, ImmunoWay, 1:1000), TGF-β1 (ab215715, Abcam, 1:1000), phospho-TGFβR I (YP1191, ImmunoWay; 1:1000), phospho-TGFβR II (A1415, Abclonal, 1:1000), phospho-Smad2 (YP1185, ImmunoWay; 1:1000), phospho-Smad3 (YP0585, ImmunoWay; 1:1000), α-SMA (bs-10196R, Bioss, 1:1000), collagen I (bs-0578R, Bioss, 1:500), collagen III (bs-0549R,Bioss, 1:500), and GAPDH (10494-1-AP, Proteintech, 1:10000), were added for overnight membrane incubation under 4°C in the shaker.

Techniques: Immunofluorescence, Staining, Expressing, Concentration Assay, Quantitative RT-PCR