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Image Search Results
Journal: International Journal of Molecular Sciences
Article Title: Phage S144, a New Polyvalent Phage Infecting Salmonella spp. and Cronobacter sakazakii
doi: 10.3390/ijms21155196
Figure Lengend Snippet: Summary of the restriction analysis of phage S144 DNA, propagated on C. sakazakii CS1, S. Infantis S15 and S. Muenster S394. DNA from phage Lambda (methylated and unmethylated) have been used as controls. The restriction site for each of the nine used enzymes is specified and in each cell, it is indicated if the DNA was cut (1, in orange) or not (0, in white). SspI and PacI, the only two enzymes able to cut S144 DNA, are in bold. RE, restriction enzymes; RS, restriction sites, met., methylated; unmet., unmethylated.
Article Snippet: S144 DNA was digested with the
Techniques: Methylation
Journal: Acta Neuropathologica Communications
Article Title: Down syndrome cell adhesion molecule like-1 (DSCAML1) links the GABA system and seizure susceptibility
doi: 10.1186/s40478-020-01082-6
Figure Lengend Snippet: DSCAML1 A2105T mutation of a patient with epilepsy and Dscaml1 A2105T knock-in mice. a, b Pedigree and genomic sequence of the DSCAML1 A2105T heterozygous patient. c Evolutionarily conserved c- terminal protein sequences of DSCAML1. d Generation of Dscaml1 A2105T knock-in mice. Negative restriction enzyme ( NarI ) selection of heterozygous founder (red arrow). e Scratch-loss of hairs and whiskers in an adult male of Dscaml1 A2105T/A2105T by hyper-grooming. f Representative ECoG of Dscaml1 A2105T/A2105T mouse. g Numbers of epileptic spike-and-wave discharges in 6 h ( n = 5–7, * p < 0.05, ** p < 0.01, Man-Whitney U - test, Error bars: s.e.m)
Article Snippet: In order to evaluate the substitution, the target region of the PCR-amplified tail DNA was cut with
Techniques: Mutagenesis, Knock-In, Sequencing, Selection