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BioExpress
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Biocell Technology
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Image Search Results
Journal:
Article Title: The centrosomal protein TACC3 is essential for hematopoietic stem cell function and genetically interfaces with p53-regulated apoptosis
doi: 10.1093/emboj/21.4.653
Figure Lengend Snippet: Fig. 8. TACC3/p53-deficient fetal liver cells rescue lymphoid cell development and expansion in Jak3-deficient mice. (A) Analysis of the number of B lymphocytes in the blood of individual Jak3-deficient mice transplanted with fetal liver cells from embryos with the indicated genotypes. (B) Growth kinetics of FACS-purified splenic B cells from transplanted Jak3-deficient mice in reponse to mitogenic treatment with αCD40 and IL-4. The number of viable cells was determined by Trypan Blue exclusion.
Article Snippet: Splenic B cells from reconstituted mice were purified by FACS (B220 + /Thy1.2 – ; 98% purity) and expanded in vitro after
Techniques: Purification