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Image Search Results
Journal: bioRxiv
Article Title: Harnessing micrometer-scale tPA beads for high plasmin generation and accelerated fibrinolysis
doi: 10.1101/2024.11.06.621942
Figure Lengend Snippet: Fibrin gels were formed with ( A ) normal pooled plasma, tissue factor (1.25 pM) and CaCl 2 (8.3 mM), ( B ) fibrinogen (2 mg/mL), glu-plasminogen (10 μM), thrombin (2 U/mL), ( C ) fibrinogen (2 mg/mL), glu-plasminogen (10 μM), thrombin (2 U/mL), α2-antiplasmin (1 μM) with free tPA or tPA-beads at 37°C. Fibrinolysis was measured by absorbance (405 nm) for tPA-beads (2.25 mU/mL) with diameters of 0.1 μm (3.55×10 10 beads/mL) and 1.0 μm (1.69×10 8 beads/mL) or free tPA (2.25 mU/mL). Each line and shaded region represent the average and standard deviation of n=3.
Article Snippet: Human fibrinogen depleted of plasminogen, von Willebrand Factor and fibronectin (FIB3), human glu-plasminogen (HPG 2001) and
Techniques: Standard Deviation