um-uc-1 Search Results


um-uc-1  (CancerTools Org)
99
CancerTools Org um-uc-1
Um Uc 1, supplied by CancerTools Org, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/um-uc-1/custom%40160436%4010%2E1016%2Fj%2Emicroc%2E2021%2E106640?v=CancerTools+Org
Average 99 stars, based on 1 article reviews
um-uc-1 - by Bioz Stars, 2026-08
99/100 stars
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um-uc-1 (rrid: cvcl_2743)  (European Collection of Authenticated Cell Cultures)
90
European Collection of Authenticated Cell Cultures um-uc-1 (rrid: cvcl_2743)
SUMOylation promotes DDX39B-mediated circNCOR1 nuclear exportation. A and B, Representative images ( A ) and histogram ( B ) of circNCOR1 location in low- and high-grade bladder cancer tissues. Scale bars, 50 μm. H&E, hematoxylin and eosin. C and D, FISH ( C ) and subcellular fraction analysis ( D ) of circNCOR1 cellular localization in bladder cancer cells. Scale bars, 5 μm. E and F, Subcellular fraction analysis of circNCOR1 in UM-UC-3 ( E ) and <t>UM-UC-1</t> ( F ) cells after overexpressing or downregulating DDX39B . G, Western blotting verified the PTM of DDX39B in bladder cancer cells. H, Western blotting of the PTM level of DDX39B after inhibitor treatment in UM-UC-3 cells. I, Subcellular fraction analysis of circNCOR1 cellular localization in indicated UM-UC-3 cells. J, Western blotting of the SUMOylation type of DDX39B in UM-UC-3 cells. K, Western blotting verified the SUMO2 modification of DDX39B after coimmunoprecipitation with anti-DDX39B and IgG control in UM-UC-3 cells. L, Schematic illustration of the SUMOylation sites on DDX39B predicted by GPS-SUMO. M, Sanger sequencing evaluation of the DDX39B K53R and DDX39B K155R mutations. N, Western blotting verified that the SUMO2 modification site of DDX39B was the K53 residue. O and P, FISH ( O ) and subcellular fraction analysis ( P ) of circNCOR1 in indicated UM-UC-3 cells. Scale bars, 5 μm. The statistical difference was assessed with the χ 2 test in B , E , F , I , and P . Error bars show the SD from three independent experiments. **, P < 0.01.
Um Uc 1 (Rrid: Cvcl 2743), supplied by European Collection of Authenticated Cell Cultures, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/um-uc-1/pmc09359746-28-35-41?v=European+Collection+of+Authenticated+Cell+Cultures
Average 90 stars, based on 1 article reviews
um-uc-1 (rrid: cvcl_2743) - by Bioz Stars, 2026-08
90/100 stars
  Buy from Supplier

Image Search Results


SUMOylation promotes DDX39B-mediated circNCOR1 nuclear exportation. A and B, Representative images ( A ) and histogram ( B ) of circNCOR1 location in low- and high-grade bladder cancer tissues. Scale bars, 50 μm. H&E, hematoxylin and eosin. C and D, FISH ( C ) and subcellular fraction analysis ( D ) of circNCOR1 cellular localization in bladder cancer cells. Scale bars, 5 μm. E and F, Subcellular fraction analysis of circNCOR1 in UM-UC-3 ( E ) and UM-UC-1 ( F ) cells after overexpressing or downregulating DDX39B . G, Western blotting verified the PTM of DDX39B in bladder cancer cells. H, Western blotting of the PTM level of DDX39B after inhibitor treatment in UM-UC-3 cells. I, Subcellular fraction analysis of circNCOR1 cellular localization in indicated UM-UC-3 cells. J, Western blotting of the SUMOylation type of DDX39B in UM-UC-3 cells. K, Western blotting verified the SUMO2 modification of DDX39B after coimmunoprecipitation with anti-DDX39B and IgG control in UM-UC-3 cells. L, Schematic illustration of the SUMOylation sites on DDX39B predicted by GPS-SUMO. M, Sanger sequencing evaluation of the DDX39B K53R and DDX39B K155R mutations. N, Western blotting verified that the SUMO2 modification site of DDX39B was the K53 residue. O and P, FISH ( O ) and subcellular fraction analysis ( P ) of circNCOR1 in indicated UM-UC-3 cells. Scale bars, 5 μm. The statistical difference was assessed with the χ 2 test in B , E , F , I , and P . Error bars show the SD from three independent experiments. **, P < 0.01.

Journal: Cancer Research

Article Title: Aberrant Nuclear Export of circNCOR1 Underlies SMAD7-Mediated Lymph Node Metastasis of Bladder Cancer

doi: 10.1158/0008-5472.CAN-21-4349

Figure Lengend Snippet: SUMOylation promotes DDX39B-mediated circNCOR1 nuclear exportation. A and B, Representative images ( A ) and histogram ( B ) of circNCOR1 location in low- and high-grade bladder cancer tissues. Scale bars, 50 μm. H&E, hematoxylin and eosin. C and D, FISH ( C ) and subcellular fraction analysis ( D ) of circNCOR1 cellular localization in bladder cancer cells. Scale bars, 5 μm. E and F, Subcellular fraction analysis of circNCOR1 in UM-UC-3 ( E ) and UM-UC-1 ( F ) cells after overexpressing or downregulating DDX39B . G, Western blotting verified the PTM of DDX39B in bladder cancer cells. H, Western blotting of the PTM level of DDX39B after inhibitor treatment in UM-UC-3 cells. I, Subcellular fraction analysis of circNCOR1 cellular localization in indicated UM-UC-3 cells. J, Western blotting of the SUMOylation type of DDX39B in UM-UC-3 cells. K, Western blotting verified the SUMO2 modification of DDX39B after coimmunoprecipitation with anti-DDX39B and IgG control in UM-UC-3 cells. L, Schematic illustration of the SUMOylation sites on DDX39B predicted by GPS-SUMO. M, Sanger sequencing evaluation of the DDX39B K53R and DDX39B K155R mutations. N, Western blotting verified that the SUMO2 modification site of DDX39B was the K53 residue. O and P, FISH ( O ) and subcellular fraction analysis ( P ) of circNCOR1 in indicated UM-UC-3 cells. Scale bars, 5 μm. The statistical difference was assessed with the χ 2 test in B , E , F , I , and P . Error bars show the SD from three independent experiments. **, P < 0.01.

Article Snippet: The human urinary bladder transitional cell carcinoma cell lines T24 (RRID: CVCL_0554), UM-UC-3 (RRID: CVCL_1783) were purchased from ATCC, RT112 (RRID: CVCL_1670) was purchased from German Collection of Microorganisms and Cell Cultures GmbH (DSMZ) and UM-UC-1 (RRID: CVCL_2743) was purchased from European Collection of Authenticated Cell Cultures (ECACC).

Techniques: Western Blot, Modification, Control, Sequencing, Residue