ul22 Search Results


catalyst formrez ul-22  (Witco Corporation)
90
Witco Corporation catalyst formrez ul-22
Catalyst Formrez Ul 22, supplied by Witco Corporation, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/catalyst formrez ul-22/product/Witco Corporation
Average 90 stars, based on 1 article reviews
catalyst formrez ul-22 - by Bioz Stars, 2026-03
90/100 stars
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fomrez®ul22 catalyst  (Crompton Corporation)
90
Crompton Corporation fomrez®ul22 catalyst
Fomrez®Ul22 Catalyst, supplied by Crompton Corporation, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/fomrez®ul22 catalyst/product/Crompton Corporation
Average 90 stars, based on 1 article reviews
fomrez®ul22 catalyst - by Bioz Stars, 2026-03
90/100 stars
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ul22  (WuXi AppTec)
90
WuXi AppTec ul22
( A ) <t>uL22</t> has three discernible states: scanning, engaged, or displaced. The maps shown are as follows: for the scanning state, the highest-resolution map available of a cytoplasmic ribosome from eukarya (EMD-40205); for the engaged state, the RAMP4-bound Sec61 map from this study, and for the displaced state, the multipass translocon (MPT)-bound map previously reported from this dataset (EMD-25994). For display, the maps were lowpass-filtered at 8 Å. ( B ) Alignment of select uL22 tail sequences. Underlines indicate the C-terminal helices annotated in the AF2 database. ( C ) Superposition of the animal and fungal uL22 tails (PDB 8AGX). ( D ) Structure of the uL22 SXKK motif, with hydrogen bonds indicated in cyan. ( E ) Comparison of the ribosome-translocon junction in the absence (top) and presence (bottom) of an ordered uL22 C-terminal helix. Note that the helix occludes the gate-side exit towards the cytoplasm.
Ul22, supplied by WuXi AppTec, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/ul22/product/WuXi AppTec
Average 90 stars, based on 1 article reviews
ul22 - by Bioz Stars, 2026-03
90/100 stars
  Buy from Supplier

Image Search Results


( A ) uL22 has three discernible states: scanning, engaged, or displaced. The maps shown are as follows: for the scanning state, the highest-resolution map available of a cytoplasmic ribosome from eukarya (EMD-40205); for the engaged state, the RAMP4-bound Sec61 map from this study, and for the displaced state, the multipass translocon (MPT)-bound map previously reported from this dataset (EMD-25994). For display, the maps were lowpass-filtered at 8 Å. ( B ) Alignment of select uL22 tail sequences. Underlines indicate the C-terminal helices annotated in the AF2 database. ( C ) Superposition of the animal and fungal uL22 tails (PDB 8AGX). ( D ) Structure of the uL22 SXKK motif, with hydrogen bonds indicated in cyan. ( E ) Comparison of the ribosome-translocon junction in the absence (top) and presence (bottom) of an ordered uL22 C-terminal helix. Note that the helix occludes the gate-side exit towards the cytoplasm.

Journal: eLife

Article Title: Structural analysis of the dynamic ribosome-translocon complex

doi: 10.7554/eLife.95814

Figure Lengend Snippet: ( A ) uL22 has three discernible states: scanning, engaged, or displaced. The maps shown are as follows: for the scanning state, the highest-resolution map available of a cytoplasmic ribosome from eukarya (EMD-40205); for the engaged state, the RAMP4-bound Sec61 map from this study, and for the displaced state, the multipass translocon (MPT)-bound map previously reported from this dataset (EMD-25994). For display, the maps were lowpass-filtered at 8 Å. ( B ) Alignment of select uL22 tail sequences. Underlines indicate the C-terminal helices annotated in the AF2 database. ( C ) Superposition of the animal and fungal uL22 tails (PDB 8AGX). ( D ) Structure of the uL22 SXKK motif, with hydrogen bonds indicated in cyan. ( E ) Comparison of the ribosome-translocon junction in the absence (top) and presence (bottom) of an ordered uL22 C-terminal helix. Note that the helix occludes the gate-side exit towards the cytoplasm.

Article Snippet: The affinity-purified ribosome fraction was analysed by immunoblotting together with 1% of the starting microsomes using antibodies against the following antigens at the indicated dilutions: RAMP4 (Abcam #ab184571, which recognizes both RAMP4 homologs; 1:5000), uL22 (Abgent, AP9892b; 1:1000), Sec61β ( ; 1:10,000), TRAPα ( ; 1:5000), STT3A (Novus Biologicals, H00003703-M02; 1:1000), TMCO1 ( ; 1:5000), CCDC47 (Bethyl Laboratories, A305-100A; 1:2000), and NOMO (Invitrogen; PA5-47534; 1:1000).

Techniques: Comparison

( A ) The uL22 CTH is observed in a reported cryo-ET average from intact membranes, EMD-15884, and at a similar occupancy to the present dataset. A similar average of hibernating ribosomes (EMD-15889) contains abundant nascent chain-like density despite the lack of a P-site tRNA, and this density appears to compete with the uL22 CTH. ( B ) The uL22 CTH binds with a similar tilt and register in the two other reported structures where those details are discernible. For display, the Sec61-RAMP4 map was supersampled at half the original pixel size.

Journal: eLife

Article Title: Structural analysis of the dynamic ribosome-translocon complex

doi: 10.7554/eLife.95814

Figure Lengend Snippet: ( A ) The uL22 CTH is observed in a reported cryo-ET average from intact membranes, EMD-15884, and at a similar occupancy to the present dataset. A similar average of hibernating ribosomes (EMD-15889) contains abundant nascent chain-like density despite the lack of a P-site tRNA, and this density appears to compete with the uL22 CTH. ( B ) The uL22 CTH binds with a similar tilt and register in the two other reported structures where those details are discernible. For display, the Sec61-RAMP4 map was supersampled at half the original pixel size.

Article Snippet: The affinity-purified ribosome fraction was analysed by immunoblotting together with 1% of the starting microsomes using antibodies against the following antigens at the indicated dilutions: RAMP4 (Abcam #ab184571, which recognizes both RAMP4 homologs; 1:5000), uL22 (Abgent, AP9892b; 1:1000), Sec61β ( ; 1:10,000), TRAPα ( ; 1:5000), STT3A (Novus Biologicals, H00003703-M02; 1:1000), TMCO1 ( ; 1:5000), CCDC47 (Bethyl Laboratories, A305-100A; 1:2000), and NOMO (Invitrogen; PA5-47534; 1:1000).

Techniques: Tomography