N/A
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TP003（Cat No.:I010952）is a nonbenzodiazepine compound that acts as a positive allosteric modulator at the benzodiazepine site of GABAA receptors. It exhibits high affinity for various receptor subtypes, with EC₅₀ values of 3.24 nM for α3β3γ2,
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93
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Tocris
tp003 Tp003, supplied by Tocris, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more https://www.bioz.com/product/tp003/TP+003/pmc04115141-105-13-14 Average 93 stars, based on 1 article reviews
tp003 - by Bioz Stars,
2026-09
93/100 stars
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90
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ANAWA Inc
tp003 Tp003, supplied by ANAWA Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more https://www.bioz.com/product/tp003/tp003/10__1523_slash_jneurosci__4404___11__2012-70-0-4 Average 90 stars, based on 1 article reviews
tp003 - by Bioz Stars,
2026-09
90/100 stars
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90
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AstraZeneca ltd
tp003 Tp003, supplied by AstraZeneca ltd, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more https://www.bioz.com/product/tp003/tp003/pm25253471-46-0-6 Average 90 stars, based on 1 article reviews
tp003 - by Bioz Stars,
2026-09
90/100 stars
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Buy from Supplier |
90
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Axon Medchem LLC
tp003 Tp003, supplied by Axon Medchem LLC, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more https://www.bioz.com/product/tp003/tp003/pm31163180-64-0-3 Average 90 stars, based on 1 article reviews
tp003 - by Bioz Stars,
2026-09
90/100 stars
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N/A
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TP 003 is a selective GABAA receptor (α3 subtype) partial agonist with affinity for the benzodiazepine binding site on human GABAA receptors. TP 003 exhibits anxiolytic-like effects in rodent behavioral models of anxiety.
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N/A
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TP003 is a non-selective benzodiazepine site agonist with EC50s of 20.3, 10.6, 3.24, 5.64 nM for α1β2γ2, α2β3γ2, α3β3γ2, α5β2γ2, respectively. TP003 induces anxiolysis via α2GABAA receptors.
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