torin1 Search Results


sictrl torin 1  (MedChemExpress)
96
MedChemExpress sictrl torin 1
( A , B ) Western blot showing mTOR and SERBP1 expression levels in control and SERBP1 knockdown U251 and U343 cells. ( C ) Sequence of mTOR 5’ UTR highlighting predicted and experimentally validated G4s, and deleted region (mTOR ΔG4). ( D ) Expression levels of wild-type mTOR 5’UTR or mTOR 5’UTR with deletion of the mTOR 23 G4 region (ΔG4) upon SERBP1 knockdown, measured in reporter constructs by normalized luciferase activity. ns, not significant; **, P ≤ 0.01. ( E-H ) Confluence of U251 and U343 glioblastoma cell lines upon SERBP1 knockdown in the presence or absence of Torin 1. Data are shown as means ± standard error; ns, not significant; ****, P ≤ 0.0001 (one-way ANOVA). Combination Index (CI) <1 indicates a synergistic effect of the combination treatment.
Sictrl Torin 1, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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torin 1  (TargetMol)
94
TargetMol torin 1
( A , B ) Western blot showing mTOR and SERBP1 expression levels in control and SERBP1 knockdown U251 and U343 cells. ( C ) Sequence of mTOR 5’ UTR highlighting predicted and experimentally validated G4s, and deleted region (mTOR ΔG4). ( D ) Expression levels of wild-type mTOR 5’UTR or mTOR 5’UTR with deletion of the mTOR 23 G4 region (ΔG4) upon SERBP1 knockdown, measured in reporter constructs by normalized luciferase activity. ns, not significant; **, P ≤ 0.01. ( E-H ) Confluence of U251 and U343 glioblastoma cell lines upon SERBP1 knockdown in the presence or absence of Torin 1. Data are shown as means ± standard error; ns, not significant; ****, P ≤ 0.0001 (one-way ANOVA). Combination Index (CI) <1 indicates a synergistic effect of the combination treatment.
Torin 1, supplied by TargetMol, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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torin 1 - by Bioz Stars, 2026-05
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torin 1  (Selleck Chemicals)
96
Selleck Chemicals torin 1
( A , B ) Western blot showing mTOR and SERBP1 expression levels in control and SERBP1 knockdown U251 and U343 cells. ( C ) Sequence of mTOR 5’ UTR highlighting predicted and experimentally validated G4s, and deleted region (mTOR ΔG4). ( D ) Expression levels of wild-type mTOR 5’UTR or mTOR 5’UTR with deletion of the mTOR 23 G4 region (ΔG4) upon SERBP1 knockdown, measured in reporter constructs by normalized luciferase activity. ns, not significant; **, P ≤ 0.01. ( E-H ) Confluence of U251 and U343 glioblastoma cell lines upon SERBP1 knockdown in the presence or absence of Torin 1. Data are shown as means ± standard error; ns, not significant; ****, P ≤ 0.0001 (one-way ANOVA). Combination Index (CI) <1 indicates a synergistic effect of the combination treatment.
Torin 1, supplied by Selleck Chemicals, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/torin 1/product/Selleck Chemicals
Average 96 stars, based on 1 article reviews
torin 1 - by Bioz Stars, 2026-05
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torin 1  (Cell Signaling Technology Inc)
95
Cell Signaling Technology Inc torin 1
( A , B ) Western blot showing mTOR and SERBP1 expression levels in control and SERBP1 knockdown U251 and U343 cells. ( C ) Sequence of mTOR 5’ UTR highlighting predicted and experimentally validated G4s, and deleted region (mTOR ΔG4). ( D ) Expression levels of wild-type mTOR 5’UTR or mTOR 5’UTR with deletion of the mTOR 23 G4 region (ΔG4) upon SERBP1 knockdown, measured in reporter constructs by normalized luciferase activity. ns, not significant; **, P ≤ 0.01. ( E-H ) Confluence of U251 and U343 glioblastoma cell lines upon SERBP1 knockdown in the presence or absence of Torin 1. Data are shown as means ± standard error; ns, not significant; ****, P ≤ 0.0001 (one-way ANOVA). Combination Index (CI) <1 indicates a synergistic effect of the combination treatment.
Torin 1, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/torin 1/product/Cell Signaling Technology Inc
Average 95 stars, based on 1 article reviews
torin 1 - by Bioz Stars, 2026-05
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torin 1  (Tocris)
96
Tocris torin 1
( A , B ) Western blot showing mTOR and SERBP1 expression levels in control and SERBP1 knockdown U251 and U343 cells. ( C ) Sequence of mTOR 5’ UTR highlighting predicted and experimentally validated G4s, and deleted region (mTOR ΔG4). ( D ) Expression levels of wild-type mTOR 5’UTR or mTOR 5’UTR with deletion of the mTOR 23 G4 region (ΔG4) upon SERBP1 knockdown, measured in reporter constructs by normalized luciferase activity. ns, not significant; **, P ≤ 0.01. ( E-H ) Confluence of U251 and U343 glioblastoma cell lines upon SERBP1 knockdown in the presence or absence of Torin 1. Data are shown as means ± standard error; ns, not significant; ****, P ≤ 0.0001 (one-way ANOVA). Combination Index (CI) <1 indicates a synergistic effect of the combination treatment.
Torin 1, supplied by Tocris, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/torin 1/product/Tocris
Average 96 stars, based on 1 article reviews
torin 1 - by Bioz Stars, 2026-05
96/100 stars
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torin1  (Tocris)
96
Tocris torin1
( A , B ) Western blot showing mTOR and SERBP1 expression levels in control and SERBP1 knockdown U251 and U343 cells. ( C ) Sequence of mTOR 5’ UTR highlighting predicted and experimentally validated G4s, and deleted region (mTOR ΔG4). ( D ) Expression levels of wild-type mTOR 5’UTR or mTOR 5’UTR with deletion of the mTOR 23 G4 region (ΔG4) upon SERBP1 knockdown, measured in reporter constructs by normalized luciferase activity. ns, not significant; **, P ≤ 0.01. ( E-H ) Confluence of U251 and U343 glioblastoma cell lines upon SERBP1 knockdown in the presence or absence of Torin 1. Data are shown as means ± standard error; ns, not significant; ****, P ≤ 0.0001 (one-way ANOVA). Combination Index (CI) <1 indicates a synergistic effect of the combination treatment.
Torin1, supplied by Tocris, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/torin1/product/Tocris
Average 96 stars, based on 1 article reviews
torin1 - by Bioz Stars, 2026-05
96/100 stars
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torin 1 tocris biosciences  (Santa Cruz Biotechnology)
93
Santa Cruz Biotechnology torin 1 tocris biosciences
( A , B ) Western blot showing mTOR and SERBP1 expression levels in control and SERBP1 knockdown U251 and U343 cells. ( C ) Sequence of mTOR 5’ UTR highlighting predicted and experimentally validated G4s, and deleted region (mTOR ΔG4). ( D ) Expression levels of wild-type mTOR 5’UTR or mTOR 5’UTR with deletion of the mTOR 23 G4 region (ΔG4) upon SERBP1 knockdown, measured in reporter constructs by normalized luciferase activity. ns, not significant; **, P ≤ 0.01. ( E-H ) Confluence of U251 and U343 glioblastoma cell lines upon SERBP1 knockdown in the presence or absence of Torin 1. Data are shown as means ± standard error; ns, not significant; ****, P ≤ 0.0001 (one-way ANOVA). Combination Index (CI) <1 indicates a synergistic effect of the combination treatment.
Torin 1 Tocris Biosciences, supplied by Santa Cruz Biotechnology, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 93 stars, based on 1 article reviews
torin 1 tocris biosciences - by Bioz Stars, 2026-05
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torin 1  (Toronto Research Chemicals)
91
Toronto Research Chemicals torin 1
( A , B ) Western blot showing mTOR and SERBP1 expression levels in control and SERBP1 knockdown U251 and U343 cells. ( C ) Sequence of mTOR 5’ UTR highlighting predicted and experimentally validated G4s, and deleted region (mTOR ΔG4). ( D ) Expression levels of wild-type mTOR 5’UTR or mTOR 5’UTR with deletion of the mTOR 23 G4 region (ΔG4) upon SERBP1 knockdown, measured in reporter constructs by normalized luciferase activity. ns, not significant; **, P ≤ 0.01. ( E-H ) Confluence of U251 and U343 glioblastoma cell lines upon SERBP1 knockdown in the presence or absence of Torin 1. Data are shown as means ± standard error; ns, not significant; ****, P ≤ 0.0001 (one-way ANOVA). Combination Index (CI) <1 indicates a synergistic effect of the combination treatment.
Torin 1, supplied by Toronto Research Chemicals, used in various techniques. Bioz Stars score: 91/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/torin 1/product/Toronto Research Chemicals
Average 91 stars, based on 1 article reviews
torin 1 - by Bioz Stars, 2026-05
91/100 stars
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torin 1  (InvivoGen)
95
InvivoGen torin 1
( A , B ) Western blot showing mTOR and SERBP1 expression levels in control and SERBP1 knockdown U251 and U343 cells. ( C ) Sequence of mTOR 5’ UTR highlighting predicted and experimentally validated G4s, and deleted region (mTOR ΔG4). ( D ) Expression levels of wild-type mTOR 5’UTR or mTOR 5’UTR with deletion of the mTOR 23 G4 region (ΔG4) upon SERBP1 knockdown, measured in reporter constructs by normalized luciferase activity. ns, not significant; **, P ≤ 0.01. ( E-H ) Confluence of U251 and U343 glioblastoma cell lines upon SERBP1 knockdown in the presence or absence of Torin 1. Data are shown as means ± standard error; ns, not significant; ****, P ≤ 0.0001 (one-way ANOVA). Combination Index (CI) <1 indicates a synergistic effect of the combination treatment.
Torin 1, supplied by InvivoGen, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/torin 1/product/InvivoGen
Average 95 stars, based on 1 article reviews
torin 1 - by Bioz Stars, 2026-05
95/100 stars
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torin 1  (BioMarin Inc)
90
BioMarin Inc torin 1
( A , B ) Western blot showing mTOR and SERBP1 expression levels in control and SERBP1 knockdown U251 and U343 cells. ( C ) Sequence of mTOR 5’ UTR highlighting predicted and experimentally validated G4s, and deleted region (mTOR ΔG4). ( D ) Expression levels of wild-type mTOR 5’UTR or mTOR 5’UTR with deletion of the mTOR 23 G4 region (ΔG4) upon SERBP1 knockdown, measured in reporter constructs by normalized luciferase activity. ns, not significant; **, P ≤ 0.01. ( E-H ) Confluence of U251 and U343 glioblastoma cell lines upon SERBP1 knockdown in the presence or absence of Torin 1. Data are shown as means ± standard error; ns, not significant; ****, P ≤ 0.0001 (one-way ANOVA). Combination Index (CI) <1 indicates a synergistic effect of the combination treatment.
Torin 1, supplied by BioMarin Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/torin 1/product/BioMarin Inc
Average 90 stars, based on 1 article reviews
torin 1 - by Bioz Stars, 2026-05
90/100 stars
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torin 1  (Cayman Chemical)
90
Cayman Chemical torin 1
( A , B ) Western blot showing mTOR and SERBP1 expression levels in control and SERBP1 knockdown U251 and U343 cells. ( C ) Sequence of mTOR 5’ UTR highlighting predicted and experimentally validated G4s, and deleted region (mTOR ΔG4). ( D ) Expression levels of wild-type mTOR 5’UTR or mTOR 5’UTR with deletion of the mTOR 23 G4 region (ΔG4) upon SERBP1 knockdown, measured in reporter constructs by normalized luciferase activity. ns, not significant; **, P ≤ 0.01. ( E-H ) Confluence of U251 and U343 glioblastoma cell lines upon SERBP1 knockdown in the presence or absence of Torin 1. Data are shown as means ± standard error; ns, not significant; ****, P ≤ 0.0001 (one-way ANOVA). Combination Index (CI) <1 indicates a synergistic effect of the combination treatment.
Torin 1, supplied by Cayman Chemical, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/torin 1/product/Cayman Chemical
Average 90 stars, based on 1 article reviews
torin 1 - by Bioz Stars, 2026-05
90/100 stars
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torin1  (LC Laboratories)
90
LC Laboratories torin1
( A , B ) Western blot showing mTOR and SERBP1 expression levels in control and SERBP1 knockdown U251 and U343 cells. ( C ) Sequence of mTOR 5’ UTR highlighting predicted and experimentally validated G4s, and deleted region (mTOR ΔG4). ( D ) Expression levels of wild-type mTOR 5’UTR or mTOR 5’UTR with deletion of the mTOR 23 G4 region (ΔG4) upon SERBP1 knockdown, measured in reporter constructs by normalized luciferase activity. ns, not significant; **, P ≤ 0.01. ( E-H ) Confluence of U251 and U343 glioblastoma cell lines upon SERBP1 knockdown in the presence or absence of Torin 1. Data are shown as means ± standard error; ns, not significant; ****, P ≤ 0.0001 (one-way ANOVA). Combination Index (CI) <1 indicates a synergistic effect of the combination treatment.
Torin1, supplied by LC Laboratories, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/torin1/product/LC Laboratories
Average 90 stars, based on 1 article reviews
torin1 - by Bioz Stars, 2026-05
90/100 stars
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Image Search Results


( A , B ) Western blot showing mTOR and SERBP1 expression levels in control and SERBP1 knockdown U251 and U343 cells. ( C ) Sequence of mTOR 5’ UTR highlighting predicted and experimentally validated G4s, and deleted region (mTOR ΔG4). ( D ) Expression levels of wild-type mTOR 5’UTR or mTOR 5’UTR with deletion of the mTOR 23 G4 region (ΔG4) upon SERBP1 knockdown, measured in reporter constructs by normalized luciferase activity. ns, not significant; **, P ≤ 0.01. ( E-H ) Confluence of U251 and U343 glioblastoma cell lines upon SERBP1 knockdown in the presence or absence of Torin 1. Data are shown as means ± standard error; ns, not significant; ****, P ≤ 0.0001 (one-way ANOVA). Combination Index (CI) <1 indicates a synergistic effect of the combination treatment.

Journal: bioRxiv

Article Title: Intrinsically disordered SERBP1 regulates translation through topology-driven G-quadruplex recognition

doi: 10.64898/2026.03.03.709370

Figure Lengend Snippet: ( A , B ) Western blot showing mTOR and SERBP1 expression levels in control and SERBP1 knockdown U251 and U343 cells. ( C ) Sequence of mTOR 5’ UTR highlighting predicted and experimentally validated G4s, and deleted region (mTOR ΔG4). ( D ) Expression levels of wild-type mTOR 5’UTR or mTOR 5’UTR with deletion of the mTOR 23 G4 region (ΔG4) upon SERBP1 knockdown, measured in reporter constructs by normalized luciferase activity. ns, not significant; **, P ≤ 0.01. ( E-H ) Confluence of U251 and U343 glioblastoma cell lines upon SERBP1 knockdown in the presence or absence of Torin 1. Data are shown as means ± standard error; ns, not significant; ****, P ≤ 0.0001 (one-way ANOVA). Combination Index (CI) <1 indicates a synergistic effect of the combination treatment.

Article Snippet: Four conditions were tested in triplicate: siCTRL + vehicle, siSERBP1 + vehicle, siCTRL + Torin 1 (MedChemExpress, NJ), and siSERBP1 + Torin 1.

Techniques: Western Blot, Expressing, Control, Knockdown, Sequencing, Construct, Luciferase, Activity Assay