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Adverse events of special interest possibly/probably related to COVID-19 vaccination among patient with inflammatory RMDs
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Adverse events of special interest possibly/probably related to COVID-19 vaccination among patient with inflammatory RMDs
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Celltrion inc tnfi
Adverse events of special interest possibly/probably related to COVID-19 vaccination among patient with inflammatory RMDs
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Truven Health tnfi
Incidence rates (95% CI) for NMSC in the Tofacitinib All group in the UC Overall Cohort, other tofacitinib programs for RA, PsA, and PsO, and <t>the</t> <t>Truven</t> database for any <t>TNFi</t> and azathioprine or 6-mercaptopurine. Abbreviations: AZA, azathioprine; N, number of patients randomized and treated; 6-MP, 6-mercaptopurine. a Curtis et al. 2017 15 . b Burmester et al. 2017 16 . c Papp et al. 2016 17 . d IRs for the Truven contextualization cohort are for events per 100 PY. e Number of treatment episodes. The study observation period for Truven cohort data was October 1, 2010, to September 30, 2015. “Any TNFi” included all patients who received TNFi alone or with immunosuppressive agents.
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Adverse events of special interest possibly/probably related to COVID-19 vaccination among patient with inflammatory RMDs

Journal: Annals of the Rheumatic Diseases

Article Title: Safety of vaccination against SARS-CoV-2 in people with rheumatic and musculoskeletal diseases: results from the EULAR Coronavirus Vaccine (COVAX) physician-reported registry

doi: 10.1136/annrheumdis-2021-221490

Figure Lengend Snippet: Adverse events of special interest possibly/probably related to COVID-19 vaccination among patient with inflammatory RMDs

Article Snippet: , Non-serious , Recovered/resolved without sequelae , Pfizer , PsA , TNFi , No.

Techniques: Injection

Incidence rates (95% CI) for NMSC in the Tofacitinib All group in the UC Overall Cohort, other tofacitinib programs for RA, PsA, and PsO, and the Truven database for any TNFi and azathioprine or 6-mercaptopurine. Abbreviations: AZA, azathioprine; N, number of patients randomized and treated; 6-MP, 6-mercaptopurine. a Curtis et al. 2017 15 . b Burmester et al. 2017 16 . c Papp et al. 2016 17 . d IRs for the Truven contextualization cohort are for events per 100 PY. e Number of treatment episodes. The study observation period for Truven cohort data was October 1, 2010, to September 30, 2015. “Any TNFi” included all patients who received TNFi alone or with immunosuppressive agents.

Journal: Inflammatory Bowel Diseases

Article Title: Tofacitinib for the Treatment of Ulcerative Colitis: Analysis of Nonmelanoma Skin Cancer Rates From the Ulcerative Colitis Clinical Program

doi: 10.1093/ibd/izab056

Figure Lengend Snippet: Incidence rates (95% CI) for NMSC in the Tofacitinib All group in the UC Overall Cohort, other tofacitinib programs for RA, PsA, and PsO, and the Truven database for any TNFi and azathioprine or 6-mercaptopurine. Abbreviations: AZA, azathioprine; N, number of patients randomized and treated; 6-MP, 6-mercaptopurine. a Curtis et al. 2017 15 . b Burmester et al. 2017 16 . c Papp et al. 2016 17 . d IRs for the Truven contextualization cohort are for events per 100 PY. e Number of treatment episodes. The study observation period for Truven cohort data was October 1, 2010, to September 30, 2015. “Any TNFi” included all patients who received TNFi alone or with immunosuppressive agents.

Article Snippet: Therefore, for contextualization purposes, the global IRs for patients with UC in this analysis are shown alongside the NMSC IR for patients with UC in external observational data from the US Truven analysis who received any TNFi, azathioprine, or 6-mercaptopurine., These data show that NMSC IRs in the UC tofacitinib Overall Cohort were generally numerically lower than those reported for TNFi, either alone or in combination, and azathioprine or 6-mercaptopurine in patients with UC in the Truven comparison cohort.

Techniques:

Demographics and Baseline Characteristics for All Patients in the  Tofacitinib  Phase 3 UC Clinical Program Following Study Drug Exposure in the Induction, Maintenance, and Overall Cohorts

Journal: Inflammatory Bowel Diseases

Article Title: Tofacitinib for the Treatment of Ulcerative Colitis: Analysis of Nonmelanoma Skin Cancer Rates From the Ulcerative Colitis Clinical Program

doi: 10.1093/ibd/izab056

Figure Lengend Snippet: Demographics and Baseline Characteristics for All Patients in the Tofacitinib Phase 3 UC Clinical Program Following Study Drug Exposure in the Induction, Maintenance, and Overall Cohorts

Article Snippet: Therefore, for contextualization purposes, the global IRs for patients with UC in this analysis are shown alongside the NMSC IR for patients with UC in external observational data from the US Truven analysis who received any TNFi, azathioprine, or 6-mercaptopurine., These data show that NMSC IRs in the UC tofacitinib Overall Cohort were generally numerically lower than those reported for TNFi, either alone or in combination, and azathioprine or 6-mercaptopurine in patients with UC in the Truven comparison cohort.

Techniques: Western Blot