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IBA Dosimetry
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TeraRecon
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Image Search Results
Journal: Frontiers in Neuroanatomy
Article Title: Impact of a deletion of the full-length and short isoform of p75NTR on cholinergic innervation and the population of postmitotic doublecortin positive cells in the dentate gyrus
doi: 10.3389/fnana.2015.00063
Figure Lengend Snippet: Impact of a deletion of p75NTR on the neuronal lineage . Mitotically active young neuronal cells were determined using NeuroD as a specific marker ( A ; the NeuroD positive cells are shown in red. DAPI-staining (in blue) was used to visualize cell nuclei). No significant differences in the number of NeuroD positive cells was noted (B) . The analysis of the postmitotical DCX-positive neurons revealed that adult p75NTR ExIV−/− mice display significant more DCX neurons of that subpopulation than age-matched controls (C) . A comparison of images of late DCX-positive neurons in the adult DG that extents its dendrites towards the molecular layer of adult p75NTR ExIV+/+ mice (D) and p75NTR ExIV+/+ mice (E) hinted for a possible difference in their morphologies (NeuroLucida: deep projection of a z-stack). Sholl analysis revealed that the morphologies of those DCX-positive neurons were different [concerning intersections (F) , nodes (G) and endings (H) ]. Scalebars: 100 μm.
Article Snippet: From these z-stacks DCX-positive neurons within the granular layer of the DG were reconstructed using NeuroLucida (MBF Biosciences, USA) and the reconstructions were analyzed with the help of NeuroExplorer (
Techniques: Marker, Staining