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Image Search Results
Journal: Drug Design, Development and Therapy
Article Title: ED-71 Prevents Glucocorticoid-Induced Osteoporosis by Regulating Osteoblast Differentiation via Notch and Wnt/β-Catenin Pathways
doi: 10.2147/DDDT.S377001
Figure Lengend Snippet: Effects of ED-71 on bone quantity and quality in MPED-induced osteoporosis mice. ( A ). a–f The representative 2D and 3D Micro-CT images of femur in CON, MPED and MPED+ED-71 groups at 4 weeks. ( B ). a–f Calcein and tetracycline labeling of mice femur at 4 weeks. The red arrow indicates the distance between calcein and tetracycline fluorescence labeling. Bar, 200μm or 100μm. ( C ). a–f The HE staining of mice femur. Bar, 1mm or 500μm. ( D – G ). Statistical analysis of bone histological parameters. Error bars stand for mean ± SD (n=5). * P < 0.05. ** P < 0.01.*** P < 0.001.
Article Snippet: The mice were subcutaneously injected with 20 mg/kg
Techniques: Micro-CT, Labeling, Fluorescence, Staining
Journal: Drug Design, Development and Therapy
Article Title: ED-71 Prevents Glucocorticoid-Induced Osteoporosis by Regulating Osteoblast Differentiation via Notch and Wnt/β-Catenin Pathways
doi: 10.2147/DDDT.S377001
Figure Lengend Snippet: Effects of ED-71 on bone quantity and quality in DEX-induced osteoporosis mice. ( A ). a–f The representative 2D and 3D Micro-CT images of femur in CON, DEX and DEX+ED-71 groups at 8 weeks. ( B ). a–f Calcein and tetracycline labeling of mice femur at 8 weeks. The red arrow indicates the distance between calcein and tetracycline fluorescence labeling. Bar, 200μm or 100μm. ( C ). a–f The HE staining of mice femur. Bar, 1mm or 500μm. ( D – G ). Statistical analysis of bone histological parameters. Error bars stand for mean ± SD (n=5). * P < 0.05. ** P < 0.01. *** P < 0.001.
Article Snippet: The mice were subcutaneously injected with 20 mg/kg
Techniques: Micro-CT, Labeling, Fluorescence, Staining