sr717 Search Results


bd126695 sr 717 mce  (MedChemExpress)
93
MedChemExpress bd126695 sr 717 mce
Bd126695 Sr 717 Mce, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 93 stars, based on 1 article reviews
bd126695 sr 717 mce - by Bioz Stars, 2026-02
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717 t8655  (TargetMol)
93
TargetMol 717 t8655
717 T8655, supplied by TargetMol, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/717 t8655/product/TargetMol
Average 93 stars, based on 1 article reviews
717 t8655 - by Bioz Stars, 2026-02
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sr 717  (MedChemExpress)
94
MedChemExpress sr 717
Cabozantinib and STING activation in macrophages favor macrophage reprograming enhancing antitumor immunity. A In THP-1–activated macrophages, cabozantinib (5µM) induced expression of type I interferon-stimulated genes (ISGs) CXCL10 , MX1 , RSAD , and OAS1 , being abrogated by STING inhibitor H-151 (1µM) ( n = 3). B STING <t>agonist</t> <t>SR-717</t> (5µM) strongly induction ISGs in THP-1 cells ( n = 3). C Murine peritoneal macrophages were obtained and treated with cabozantinib (10µM) and STING agonist DMXAA. mRNA levels indicative of M1/M2 polarization were determined after 24 h. ( n = 4). Student t test or one-way ANOVA with a Newman-Keuls post hoc test with * p < 0.05, ** p < 0.01. * p < 0.05,
Sr 717, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/sr 717/product/MedChemExpress
Average 94 stars, based on 1 article reviews
sr 717 - by Bioz Stars, 2026-02
94/100 stars
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717 lithium s0853  (Selleck Chemicals)
93
Selleck Chemicals 717 lithium s0853
Cabozantinib and STING activation in macrophages favor macrophage reprograming enhancing antitumor immunity. A In THP-1–activated macrophages, cabozantinib (5µM) induced expression of type I interferon-stimulated genes (ISGs) CXCL10 , MX1 , RSAD , and OAS1 , being abrogated by STING inhibitor H-151 (1µM) ( n = 3). B STING <t>agonist</t> <t>SR-717</t> (5µM) strongly induction ISGs in THP-1 cells ( n = 3). C Murine peritoneal macrophages were obtained and treated with cabozantinib (10µM) and STING agonist DMXAA. mRNA levels indicative of M1/M2 polarization were determined after 24 h. ( n = 4). Student t test or one-way ANOVA with a Newman-Keuls post hoc test with * p < 0.05, ** p < 0.01. * p < 0.05,
717 Lithium S0853, supplied by Selleck Chemicals, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/717 lithium s0853/product/Selleck Chemicals
Average 93 stars, based on 1 article reviews
717 lithium s0853 - by Bioz Stars, 2026-02
93/100 stars
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sting agonist sr-717  (BioMimetic Therapeutics)
90
BioMimetic Therapeutics sting agonist sr-717
Cabozantinib and STING activation in macrophages favor macrophage reprograming enhancing antitumor immunity. A In THP-1–activated macrophages, cabozantinib (5µM) induced expression of type I interferon-stimulated genes (ISGs) CXCL10 , MX1 , RSAD , and OAS1 , being abrogated by STING inhibitor H-151 (1µM) ( n = 3). B STING <t>agonist</t> <t>SR-717</t> (5µM) strongly induction ISGs in THP-1 cells ( n = 3). C Murine peritoneal macrophages were obtained and treated with cabozantinib (10µM) and STING agonist DMXAA. mRNA levels indicative of M1/M2 polarization were determined after 24 h. ( n = 4). Student t test or one-way ANOVA with a Newman-Keuls post hoc test with * p < 0.05, ** p < 0.01. * p < 0.05,
Sting Agonist Sr 717, supplied by BioMimetic Therapeutics, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/sting agonist sr-717/product/BioMimetic Therapeutics
Average 90 stars, based on 1 article reviews
sting agonist sr-717 - by Bioz Stars, 2026-02
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sr-717  (NanoCarrier Co)
90
NanoCarrier Co sr-717
Cabozantinib and STING activation in macrophages favor macrophage reprograming enhancing antitumor immunity. A In THP-1–activated macrophages, cabozantinib (5µM) induced expression of type I interferon-stimulated genes (ISGs) CXCL10 , MX1 , RSAD , and OAS1 , being abrogated by STING inhibitor H-151 (1µM) ( n = 3). B STING <t>agonist</t> <t>SR-717</t> (5µM) strongly induction ISGs in THP-1 cells ( n = 3). C Murine peritoneal macrophages were obtained and treated with cabozantinib (10µM) and STING agonist DMXAA. mRNA levels indicative of M1/M2 polarization were determined after 24 h. ( n = 4). Student t test or one-way ANOVA with a Newman-Keuls post hoc test with * p < 0.05, ** p < 0.01. * p < 0.05,
Sr 717, supplied by NanoCarrier Co, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/sr-717/product/NanoCarrier Co
Average 90 stars, based on 1 article reviews
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Image Search Results


Cabozantinib and STING activation in macrophages favor macrophage reprograming enhancing antitumor immunity. A In THP-1–activated macrophages, cabozantinib (5µM) induced expression of type I interferon-stimulated genes (ISGs) CXCL10 , MX1 , RSAD , and OAS1 , being abrogated by STING inhibitor H-151 (1µM) ( n = 3). B STING agonist SR-717 (5µM) strongly induction ISGs in THP-1 cells ( n = 3). C Murine peritoneal macrophages were obtained and treated with cabozantinib (10µM) and STING agonist DMXAA. mRNA levels indicative of M1/M2 polarization were determined after 24 h. ( n = 4). Student t test or one-way ANOVA with a Newman-Keuls post hoc test with * p < 0.05, ** p < 0.01. * p < 0.05,

Journal: Journal of Experimental & Clinical Cancer Research : CR

Article Title: Immune remodeling via mitochondria-dependent STING activation enhances cabozantinib response in hepatocellular carcinoma

doi: 10.1186/s13046-025-03632-z

Figure Lengend Snippet: Cabozantinib and STING activation in macrophages favor macrophage reprograming enhancing antitumor immunity. A In THP-1–activated macrophages, cabozantinib (5µM) induced expression of type I interferon-stimulated genes (ISGs) CXCL10 , MX1 , RSAD , and OAS1 , being abrogated by STING inhibitor H-151 (1µM) ( n = 3). B STING agonist SR-717 (5µM) strongly induction ISGs in THP-1 cells ( n = 3). C Murine peritoneal macrophages were obtained and treated with cabozantinib (10µM) and STING agonist DMXAA. mRNA levels indicative of M1/M2 polarization were determined after 24 h. ( n = 4). Student t test or one-way ANOVA with a Newman-Keuls post hoc test with * p < 0.05, ** p < 0.01. * p < 0.05,

Article Snippet: Cabozantinib, Lenvatinib (HY-10981), H-151 (HY-112693), DMXAA (HY10964), SR-717 ( HY131454 ), MSA-2 ( HY136927 ), were from MedChem Express (Monmouth Junction, NJ, USA).

Techniques: Activation Assay, Expressing