spon1 Search Results


gene exp spon1 hs01120488 m1  (Thermo Fisher)
88
Thermo Fisher gene exp spon1 hs01120488 m1
Gene Exp Spon1 Hs01120488 M1, supplied by Thermo Fisher, used in various techniques. Bioz Stars score: 88/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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f spondin neutralizing antibody  (R&D Systems)
90
R&D Systems f spondin neutralizing antibody
F Spondin Neutralizing Antibody, supplied by R&D Systems, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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f spondin  (ProSci Incorporated)
90
ProSci Incorporated f spondin
F Spondin, supplied by ProSci Incorporated, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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antispon1  (OriGene)
93
OriGene antispon1
Antispon1, supplied by OriGene, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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gene exp spon1 bt03259574 m1  (Thermo Fisher)
92
Thermo Fisher gene exp spon1 bt03259574 m1
Gene Exp Spon1 Bt03259574 M1, supplied by Thermo Fisher, used in various techniques. Bioz Stars score: 92/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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spon1  (Cusabio)
92
Cusabio spon1
Spon1, supplied by Cusabio, used in various techniques. Bioz Stars score: 92/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 92 stars, based on 1 article reviews
spon1 - by Bioz Stars, 2026-03
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snp spon1 c 55174 30  (Thermo Fisher)
90
Thermo Fisher snp spon1 c 55174 30
Rates of change in cognitively normal older adults. Rates of change are presented for (a) global cognition (SD/year), (b) verbal episodic memory (SD/year) and (c) AIBL-PACC (4×SD/year) in cognitively normal older adults ( n = 590). <t>SPON1</t> A– (grey) and SPON1 A+ (black). Controlling for APOE ɛ 4 and amyloid-β status, AIBL-PACC analysis also controlled for age. Error bars represent time dependent standard error, * p < 0.05.
Snp Spon1 C 55174 30, supplied by Thermo Fisher, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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recombinant mouse spon1  (R&D Systems)
93
R&D Systems recombinant mouse spon1
Rates of change in cognitively normal older adults. Rates of change are presented for (a) global cognition (SD/year), (b) verbal episodic memory (SD/year) and (c) AIBL-PACC (4×SD/year) in cognitively normal older adults ( n = 590). <t>SPON1</t> A– (grey) and SPON1 A+ (black). Controlling for APOE ɛ 4 and amyloid-β status, AIBL-PACC analysis also controlled for age. Error bars represent time dependent standard error, * p < 0.05.
Recombinant Mouse Spon1, supplied by R&D Systems, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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gene exp spon1 mm00523995 m1  (Thermo Fisher)
90
Thermo Fisher gene exp spon1 mm00523995 m1
A. Schematic illustrating experimental design of slice physiology experiments from molecularly defined MHb neurons. B. The spatial distributions of recorded cells. Blue: Cck (+) cells, grey: <t>Spon1</t> (+) cells. C. Left: Example resting firing rate of Cck (+) (top) and Spon1 (+) (bottom) cells recorded in whole cell mode. Right: Basal firing rate was higher for Spon1 (+) cells (t-test with Welch’s correction for unequal variance: t(16.46) = 4.24, p=0.0006). D. Left: Example of Cck (+) (top) and Spon1 (+) (bottom) cells’ traces during 40 pA current injection. Right: Spon1 (+) cells spiked more in response to current injection (40 pA steps, 800 ms duration). Two-way repeated measures ANOVA [Current x Cell Type]: Main effect of Current, F(6,132)=7.99, p<0.001; Main Effect of Cell Type, F(1,22)=4.70, p=0.041; No Current x Cell Type interaction, F(6,132)=1.94, p=0.079. E. Spon1 (+) cells exhibited a shorter latency to spike during current injections. Two-way repeated measures ANOVA [Current x Cell Type]: Main effect of Current, F(5,100)=11.31, p<0.001; Main Effect of Cell Type, F(1,20)=7.35, p=0.014; No Current x Cell Type interaction, F(5,100)=0.66, p=0.65. Related to Figure S6.
Gene Exp Spon1 Mm00523995 M1, supplied by Thermo Fisher, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 90 stars, based on 1 article reviews
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mouse spon1 elisa  (Cusabio)
91
Cusabio mouse spon1 elisa
A. Schematic illustrating experimental design of slice physiology experiments from molecularly defined MHb neurons. B. The spatial distributions of recorded cells. Blue: Cck (+) cells, grey: <t>Spon1</t> (+) cells. C. Left: Example resting firing rate of Cck (+) (top) and Spon1 (+) (bottom) cells recorded in whole cell mode. Right: Basal firing rate was higher for Spon1 (+) cells (t-test with Welch’s correction for unequal variance: t(16.46) = 4.24, p=0.0006). D. Left: Example of Cck (+) (top) and Spon1 (+) (bottom) cells’ traces during 40 pA current injection. Right: Spon1 (+) cells spiked more in response to current injection (40 pA steps, 800 ms duration). Two-way repeated measures ANOVA [Current x Cell Type]: Main effect of Current, F(6,132)=7.99, p<0.001; Main Effect of Cell Type, F(1,22)=4.70, p=0.041; No Current x Cell Type interaction, F(6,132)=1.94, p=0.079. E. Spon1 (+) cells exhibited a shorter latency to spike during current injections. Two-way repeated measures ANOVA [Current x Cell Type]: Main effect of Current, F(5,100)=11.31, p<0.001; Main Effect of Cell Type, F(1,20)=7.35, p=0.014; No Current x Cell Type interaction, F(5,100)=0.66, p=0.65. Related to Figure S6.
Mouse Spon1 Elisa, supplied by Cusabio, used in various techniques. Bioz Stars score: 91/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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recombinant proteins  (R&D Systems)
86
R&D Systems recombinant proteins
A. Schematic illustrating experimental design of slice physiology experiments from molecularly defined MHb neurons. B. The spatial distributions of recorded cells. Blue: Cck (+) cells, grey: <t>Spon1</t> (+) cells. C. Left: Example resting firing rate of Cck (+) (top) and Spon1 (+) (bottom) cells recorded in whole cell mode. Right: Basal firing rate was higher for Spon1 (+) cells (t-test with Welch’s correction for unequal variance: t(16.46) = 4.24, p=0.0006). D. Left: Example of Cck (+) (top) and Spon1 (+) (bottom) cells’ traces during 40 pA current injection. Right: Spon1 (+) cells spiked more in response to current injection (40 pA steps, 800 ms duration). Two-way repeated measures ANOVA [Current x Cell Type]: Main effect of Current, F(6,132)=7.99, p<0.001; Main Effect of Cell Type, F(1,22)=4.70, p=0.041; No Current x Cell Type interaction, F(6,132)=1.94, p=0.079. E. Spon1 (+) cells exhibited a shorter latency to spike during current injections. Two-way repeated measures ANOVA [Current x Cell Type]: Main effect of Current, F(5,100)=11.31, p<0.001; Main Effect of Cell Type, F(1,20)=7.35, p=0.014; No Current x Cell Type interaction, F(5,100)=0.66, p=0.65. Related to Figure S6.
Recombinant Proteins, supplied by R&D Systems, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Image Search Results


Rates of change in cognitively normal older adults. Rates of change are presented for (a) global cognition (SD/year), (b) verbal episodic memory (SD/year) and (c) AIBL-PACC (4×SD/year) in cognitively normal older adults ( n = 590). SPON1 A– (grey) and SPON1 A+ (black). Controlling for APOE ɛ 4 and amyloid-β status, AIBL-PACC analysis also controlled for age. Error bars represent time dependent standard error, * p < 0.05.

Journal: Journal of Alzheimer's Disease Reports

Article Title: SPON1 Is Associated with Amyloid-β and APOE ε4-Related Cognitive Decline in Cognitively Normal Adults

doi: 10.3233/ADR-200246

Figure Lengend Snippet: Rates of change in cognitively normal older adults. Rates of change are presented for (a) global cognition (SD/year), (b) verbal episodic memory (SD/year) and (c) AIBL-PACC (4×SD/year) in cognitively normal older adults ( n = 590). SPON1 A– (grey) and SPON1 A+ (black). Controlling for APOE ɛ 4 and amyloid-β status, AIBL-PACC analysis also controlled for age. Error bars represent time dependent standard error, * p < 0.05.

Article Snippet: QIAamp DNA Blood Maxi Kits (Qiagen, Hilden, Germany) were used for DNA extraction and TaqMan® genotyping assays (Life Technologies, Carlsbad, CA) for APOE (rs7412, assay ID: C___904973_10; rs429358, assay ID: C___3084793_20) and SPON1 (rs11023139, assay ID: C___55174_30) genotyping.

Techniques:

Rates of change in cognitively normal adults stratified by amyloid-β status, APOE ɛ 4 interaction. Rates of change are presented for (a, d) global cognition (SD/year), (b, e) verbal episodic memory (SD/year) and (c, f) AIBL-PACC (4×SD/year) in cognitively normal older adults with low (a, b, c; n = 336) or high (d, e, f; n = 254) amyloid-β. APOE ɛ 4-ve/ SPON1 A– (green), APOE ɛ 4-ve/ SPON1 A+ (blue), APOE ɛ 4 + ve/ SPON1 A– (orange), APOE ɛ 4 + ve/ SPON1 A+ (red). Controlling for age in AIBL-PACC. Error bars represent time dependent standard error. * p < 0.05 when comparing to the APOE ɛ 4-ve/ SPON1 A– carrier group, † p < 0.05 when comparing to the APOE ɛ 4-ve/ SPON1 A+ group, ‡ p < 0.05 when comparing to the APOE ɛ 4 + ve/ SPON1 A– carrier.

Journal: Journal of Alzheimer's Disease Reports

Article Title: SPON1 Is Associated with Amyloid-β and APOE ε4-Related Cognitive Decline in Cognitively Normal Adults

doi: 10.3233/ADR-200246

Figure Lengend Snippet: Rates of change in cognitively normal adults stratified by amyloid-β status, APOE ɛ 4 interaction. Rates of change are presented for (a, d) global cognition (SD/year), (b, e) verbal episodic memory (SD/year) and (c, f) AIBL-PACC (4×SD/year) in cognitively normal older adults with low (a, b, c; n = 336) or high (d, e, f; n = 254) amyloid-β. APOE ɛ 4-ve/ SPON1 A– (green), APOE ɛ 4-ve/ SPON1 A+ (blue), APOE ɛ 4 + ve/ SPON1 A– (orange), APOE ɛ 4 + ve/ SPON1 A+ (red). Controlling for age in AIBL-PACC. Error bars represent time dependent standard error. * p < 0.05 when comparing to the APOE ɛ 4-ve/ SPON1 A– carrier group, † p < 0.05 when comparing to the APOE ɛ 4-ve/ SPON1 A+ group, ‡ p < 0.05 when comparing to the APOE ɛ 4 + ve/ SPON1 A– carrier.

Article Snippet: QIAamp DNA Blood Maxi Kits (Qiagen, Hilden, Germany) were used for DNA extraction and TaqMan® genotyping assays (Life Technologies, Carlsbad, CA) for APOE (rs7412, assay ID: C___904973_10; rs429358, assay ID: C___3084793_20) and SPON1 (rs11023139, assay ID: C___55174_30) genotyping.

Techniques:

A. Schematic illustrating experimental design of slice physiology experiments from molecularly defined MHb neurons. B. The spatial distributions of recorded cells. Blue: Cck (+) cells, grey: Spon1 (+) cells. C. Left: Example resting firing rate of Cck (+) (top) and Spon1 (+) (bottom) cells recorded in whole cell mode. Right: Basal firing rate was higher for Spon1 (+) cells (t-test with Welch’s correction for unequal variance: t(16.46) = 4.24, p=0.0006). D. Left: Example of Cck (+) (top) and Spon1 (+) (bottom) cells’ traces during 40 pA current injection. Right: Spon1 (+) cells spiked more in response to current injection (40 pA steps, 800 ms duration). Two-way repeated measures ANOVA [Current x Cell Type]: Main effect of Current, F(6,132)=7.99, p<0.001; Main Effect of Cell Type, F(1,22)=4.70, p=0.041; No Current x Cell Type interaction, F(6,132)=1.94, p=0.079. E. Spon1 (+) cells exhibited a shorter latency to spike during current injections. Two-way repeated measures ANOVA [Current x Cell Type]: Main effect of Current, F(5,100)=11.31, p<0.001; Main Effect of Cell Type, F(1,20)=7.35, p=0.014; No Current x Cell Type interaction, F(5,100)=0.66, p=0.65. Related to Figure S6.

Journal: Neuron

Article Title: Transcriptional and Spatial Resolution of Cell Types in the Mammalian Habenula

doi: 10.1016/j.neuron.2020.03.011

Figure Lengend Snippet: A. Schematic illustrating experimental design of slice physiology experiments from molecularly defined MHb neurons. B. The spatial distributions of recorded cells. Blue: Cck (+) cells, grey: Spon1 (+) cells. C. Left: Example resting firing rate of Cck (+) (top) and Spon1 (+) (bottom) cells recorded in whole cell mode. Right: Basal firing rate was higher for Spon1 (+) cells (t-test with Welch’s correction for unequal variance: t(16.46) = 4.24, p=0.0006). D. Left: Example of Cck (+) (top) and Spon1 (+) (bottom) cells’ traces during 40 pA current injection. Right: Spon1 (+) cells spiked more in response to current injection (40 pA steps, 800 ms duration). Two-way repeated measures ANOVA [Current x Cell Type]: Main effect of Current, F(6,132)=7.99, p<0.001; Main Effect of Cell Type, F(1,22)=4.70, p=0.041; No Current x Cell Type interaction, F(6,132)=1.94, p=0.079. E. Spon1 (+) cells exhibited a shorter latency to spike during current injections. Two-way repeated measures ANOVA [Current x Cell Type]: Main effect of Current, F(5,100)=11.31, p<0.001; Main Effect of Cell Type, F(1,20)=7.35, p=0.014; No Current x Cell Type interaction, F(5,100)=0.66, p=0.65. Related to Figure S6.

Article Snippet: TaqMan® Assays-Mm-Spon1 , Thermo Fisher Scientific , Mm00523995_m1.

Techniques: Injection

KEY RESOURCES TABLE

Journal: Neuron

Article Title: Transcriptional and Spatial Resolution of Cell Types in the Mammalian Habenula

doi: 10.1016/j.neuron.2020.03.011

Figure Lengend Snippet: KEY RESOURCES TABLE

Article Snippet: TaqMan® Assays-Mm-Spon1 , Thermo Fisher Scientific , Mm00523995_m1.

Techniques: Recombinant, RNAscope, Multiplex Assay, Gene Expression, Software