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Image Search Results
Journal: ACS infectious diseases
Article Title: Correlating Drug-Target Residence Time and Post-Antibiotic Effect: Insight into Target Vulnerability
doi: 10.1021/acsinfecdis.9b00484
Figure Lengend Snippet: Residence time and cellular PAE values of the macrolide ribosome inhibitors
Article Snippet: Erythromycin was obtained from Sigma-Aldrich, azithromycin from TCI America,
Techniques:
Journal: ACS infectious diseases
Article Title: Correlating Drug-Target Residence Time and Post-Antibiotic Effect: Insight into Target Vulnerability
doi: 10.1021/acsinfecdis.9b00484
Figure Lengend Snippet: Input and output values of thermodynamic and kinetic parameters for the selected macrolides.
Article Snippet: Erythromycin was obtained from Sigma-Aldrich, azithromycin from TCI America,
Techniques:
Journal: Nature
Article Title: Aspm knockout ferret reveals an evolutionary mechanism governing cerebral cortical size
doi: 10.1038/s41586-018-0035-0
Figure Lengend Snippet: a , aPKCζ at the ventricular surface is decreased in Aspm−/− mice. b , Depletion of ASPM in H4 cells prevents recruitment of aPKCζ and PAR6α to the centrosomes. c , ASPM and aPKCζ co-immunoprecipitate from Hela cells. d , e , Loss of Aspm decreases ventricular surface staining for Ninein. f , Depletion of ASPM and aPKCζ prevents recruitment of Ninein to the centrosomes in H4 cells. g , Levels of aPKCζ, Par6α, and Ninein are unchanged in Aspm−/− mouse embryonic fibroblasts. See Methods for reproducibility. For gel source data, see . Scale bars: a , 50 μm; b – f , 5 μm.
Article Snippet: The following antibodies were used at 1:100 – 1:2000: Centrin (Millipore 20H5), Par6α (SCBT sc-14405), Par6α (Abcam ab180159), β-actin (Proteintech 20536-1-AP),
Techniques: Staining