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SpaIM comprises an ST <t>autoencoder</t> and an ST generator. Both the ST autoencoder and the ST generator are built on the multilayer recursive style transfer (ReST) layers.
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SpaIM comprises an ST autoencoder and an ST generator. Both the ST autoencoder and the ST generator are built on the multilayer recursive style transfer (ReST) layers.

Journal: Nature Communications

Article Title: SpaIM: single-cell spatial transcriptomics imputation via style transfer

doi: 10.1038/s41467-025-63185-9

Figure Lengend Snippet: SpaIM comprises an ST autoencoder and an ST generator. Both the ST autoencoder and the ST generator are built on the multilayer recursive style transfer (ReST) layers.

Article Snippet: Spatial transcriptomics (ST) autoencoder The ST autoencoder (Fig. ) comprises multilayer ReST encoders.

Techniques:

a Benchmarking results on the NanoString CosMx spatial transcriptomics dataset (Lung5–rep3), using evaluation metrics including structural similarity index measure (SSIM) and Jaccard similarity (JS). Data are presented as mean values ± 95% confidence intervals across predicted genes ( \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$n$$\end{document} n = 2,038). b Spatial visualization of cell types in the whole slide. c Spatial visualization of cell types in specific field of views (FOVs).

Journal: Nature Communications

Article Title: SpaIM: single-cell spatial transcriptomics imputation via style transfer

doi: 10.1038/s41467-025-63185-9

Figure Lengend Snippet: a Benchmarking results on the NanoString CosMx spatial transcriptomics dataset (Lung5–rep3), using evaluation metrics including structural similarity index measure (SSIM) and Jaccard similarity (JS). Data are presented as mean values ± 95% confidence intervals across predicted genes ( \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$n$$\end{document} n = 2,038). b Spatial visualization of cell types in the whole slide. c Spatial visualization of cell types in specific field of views (FOVs).

Article Snippet: Spatial transcriptomics (ST) autoencoder The ST autoencoder (Fig. ) comprises multilayer ReST encoders.

Techniques: