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avidin biotin blocking kit  (Vector Laboratories)
96
Vector Laboratories avidin biotin blocking kit
Avidin Biotin Blocking Kit, supplied by Vector Laboratories, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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avidin biotin blocking kit - by Bioz Stars, 2026-06
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quantidade nome comum gênero ou espécie tipo de fixação 1 cuíca cauda de rato metachirus nudicaudatus seca 1 cutia dasyprocta sp  (Seca)
86
Seca quantidade nome comum gênero ou espécie tipo de fixação 1 cuíca cauda de rato metachirus nudicaudatus seca 1 cutia dasyprocta sp
Quantidade Nome Comum Gênero Ou Espécie Tipo De Fixação 1 Cuíca Cauda De Rato Metachirus Nudicaudatus Seca 1 Cutia Dasyprocta Sp, supplied by Seca, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 86 stars, based on 1 article reviews
quantidade nome comum gênero ou espécie tipo de fixação 1 cuíca cauda de rato metachirus nudicaudatus seca 1 cutia dasyprocta sp - by Bioz Stars, 2026-06
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recombinant mouse sparc  (R&D Systems)
90
R&D Systems recombinant mouse sparc
<t>SPARC</t> and laminin-α1β1γ1, two proteins abundantly found in EPC-CM, control acinar differentiation. ( a ) RT-qPCR analysis of acinar and control genes reported to β-actin in pancreatic explants cultured for 3 days in control medium (Ctrl) and in the presence of SPARC (+SPARC). Addition of SPARC favors acinar differentiation as demonstrated by increased levels of acinar markers ( Cpa and Amy ) and pro-acinar transcription factors ( Rbpjl and Ptf1a ). Expression level of control genes ( Rbpj and E-Cadherin ) are not affected. ( b ) RT-qPCR analysis of acinar and control genes reported to β-actin in pancreatic explants cultured for 3 days in control medium (Ctrl) and in the presence of laminin-α1β1γ1. In the presence of laminin-α1β1γ1, the expression of acinar markers ( Cpa and Amy ) and pro-acinar transcription factors ( Rbpjl and Ptf1a ) is reduced as compared to control explants. Expression level of control genes ( Rbpjl and E-Cadherin ) is not affected. (Mann-Whitney: *p < 0.05). ( c ) Immunofluorescence for the acinar differentiation marker Amylase (green) and the pancreatic epithelium marker (E-Cadherin, red) in explants at 3 days, as indicated. As compared to control explants showing acinar differentiation (Amylase + cells), addition of SPARC stimulates, while laminin-α1β1γ1 decreases the Amylase signal.
Recombinant Mouse Sparc, supplied by R&D Systems, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/sp/pmc06389953-276-7-10?v=R%26D+Systems
Average 90 stars, based on 1 article reviews
recombinant mouse sparc - by Bioz Stars, 2026-06
90/100 stars
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sandwich elisa quantikine total human mmp 1 kit  (R&D Systems)
93
R&D Systems sandwich elisa quantikine total human mmp 1 kit
<t>SPARC</t> and laminin-α1β1γ1, two proteins abundantly found in EPC-CM, control acinar differentiation. ( a ) RT-qPCR analysis of acinar and control genes reported to β-actin in pancreatic explants cultured for 3 days in control medium (Ctrl) and in the presence of SPARC (+SPARC). Addition of SPARC favors acinar differentiation as demonstrated by increased levels of acinar markers ( Cpa and Amy ) and pro-acinar transcription factors ( Rbpjl and Ptf1a ). Expression level of control genes ( Rbpj and E-Cadherin ) are not affected. ( b ) RT-qPCR analysis of acinar and control genes reported to β-actin in pancreatic explants cultured for 3 days in control medium (Ctrl) and in the presence of laminin-α1β1γ1. In the presence of laminin-α1β1γ1, the expression of acinar markers ( Cpa and Amy ) and pro-acinar transcription factors ( Rbpjl and Ptf1a ) is reduced as compared to control explants. Expression level of control genes ( Rbpjl and E-Cadherin ) is not affected. (Mann-Whitney: *p < 0.05). ( c ) Immunofluorescence for the acinar differentiation marker Amylase (green) and the pancreatic epithelium marker (E-Cadherin, red) in explants at 3 days, as indicated. As compared to control explants showing acinar differentiation (Amylase + cells), addition of SPARC stimulates, while laminin-α1β1γ1 decreases the Amylase signal.
Sandwich Elisa Quantikine Total Human Mmp 1 Kit, supplied by R&D Systems, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 93 stars, based on 1 article reviews
sandwich elisa quantikine total human mmp 1 kit - by Bioz Stars, 2026-06
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protein acidic  (R&D Systems)
93
R&D Systems protein acidic
<t>SPARC</t> and laminin-α1β1γ1, two proteins abundantly found in EPC-CM, control acinar differentiation. ( a ) RT-qPCR analysis of acinar and control genes reported to β-actin in pancreatic explants cultured for 3 days in control medium (Ctrl) and in the presence of SPARC (+SPARC). Addition of SPARC favors acinar differentiation as demonstrated by increased levels of acinar markers ( Cpa and Amy ) and pro-acinar transcription factors ( Rbpjl and Ptf1a ). Expression level of control genes ( Rbpj and E-Cadherin ) are not affected. ( b ) RT-qPCR analysis of acinar and control genes reported to β-actin in pancreatic explants cultured for 3 days in control medium (Ctrl) and in the presence of laminin-α1β1γ1. In the presence of laminin-α1β1γ1, the expression of acinar markers ( Cpa and Amy ) and pro-acinar transcription factors ( Rbpjl and Ptf1a ) is reduced as compared to control explants. Expression level of control genes ( Rbpjl and E-Cadherin ) is not affected. (Mann-Whitney: *p < 0.05). ( c ) Immunofluorescence for the acinar differentiation marker Amylase (green) and the pancreatic epithelium marker (E-Cadherin, red) in explants at 3 days, as indicated. As compared to control explants showing acinar differentiation (Amylase + cells), addition of SPARC stimulates, while laminin-α1β1γ1 decreases the Amylase signal.
Protein Acidic, supplied by R&D Systems, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 93 stars, based on 1 article reviews
protein acidic - by Bioz Stars, 2026-06
93/100 stars
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sars cov 2 spike s1 protein  (ACROBiosystems)
95
ACROBiosystems sars cov 2 spike s1 protein
<t>SPARC</t> and laminin-α1β1γ1, two proteins abundantly found in EPC-CM, control acinar differentiation. ( a ) RT-qPCR analysis of acinar and control genes reported to β-actin in pancreatic explants cultured for 3 days in control medium (Ctrl) and in the presence of SPARC (+SPARC). Addition of SPARC favors acinar differentiation as demonstrated by increased levels of acinar markers ( Cpa and Amy ) and pro-acinar transcription factors ( Rbpjl and Ptf1a ). Expression level of control genes ( Rbpj and E-Cadherin ) are not affected. ( b ) RT-qPCR analysis of acinar and control genes reported to β-actin in pancreatic explants cultured for 3 days in control medium (Ctrl) and in the presence of laminin-α1β1γ1. In the presence of laminin-α1β1γ1, the expression of acinar markers ( Cpa and Amy ) and pro-acinar transcription factors ( Rbpjl and Ptf1a ) is reduced as compared to control explants. Expression level of control genes ( Rbpjl and E-Cadherin ) is not affected. (Mann-Whitney: *p < 0.05). ( c ) Immunofluorescence for the acinar differentiation marker Amylase (green) and the pancreatic epithelium marker (E-Cadherin, red) in explants at 3 days, as indicated. As compared to control explants showing acinar differentiation (Amylase + cells), addition of SPARC stimulates, while laminin-α1β1γ1 decreases the Amylase signal.
Sars Cov 2 Spike S1 Protein, supplied by ACROBiosystems, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 95 stars, based on 1 article reviews
sars cov 2 spike s1 protein - by Bioz Stars, 2026-06
95/100 stars
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pbs t biotinylated anti mouse igg antibody  (Jackson Immuno)
93
Jackson Immuno pbs t biotinylated anti mouse igg antibody
<t>SPARC</t> and laminin-α1β1γ1, two proteins abundantly found in EPC-CM, control acinar differentiation. ( a ) RT-qPCR analysis of acinar and control genes reported to β-actin in pancreatic explants cultured for 3 days in control medium (Ctrl) and in the presence of SPARC (+SPARC). Addition of SPARC favors acinar differentiation as demonstrated by increased levels of acinar markers ( Cpa and Amy ) and pro-acinar transcription factors ( Rbpjl and Ptf1a ). Expression level of control genes ( Rbpj and E-Cadherin ) are not affected. ( b ) RT-qPCR analysis of acinar and control genes reported to β-actin in pancreatic explants cultured for 3 days in control medium (Ctrl) and in the presence of laminin-α1β1γ1. In the presence of laminin-α1β1γ1, the expression of acinar markers ( Cpa and Amy ) and pro-acinar transcription factors ( Rbpjl and Ptf1a ) is reduced as compared to control explants. Expression level of control genes ( Rbpjl and E-Cadherin ) is not affected. (Mann-Whitney: *p < 0.05). ( c ) Immunofluorescence for the acinar differentiation marker Amylase (green) and the pancreatic epithelium marker (E-Cadherin, red) in explants at 3 days, as indicated. As compared to control explants showing acinar differentiation (Amylase + cells), addition of SPARC stimulates, while laminin-α1β1γ1 decreases the Amylase signal.
Pbs T Biotinylated Anti Mouse Igg Antibody, supplied by Jackson Immuno, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 93 stars, based on 1 article reviews
pbs t biotinylated anti mouse igg antibody - by Bioz Stars, 2026-06
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goat anti human f ab 2  (Jackson Immuno)
93
Jackson Immuno goat anti human f ab 2
<t>SPARC</t> and laminin-α1β1γ1, two proteins abundantly found in EPC-CM, control acinar differentiation. ( a ) RT-qPCR analysis of acinar and control genes reported to β-actin in pancreatic explants cultured for 3 days in control medium (Ctrl) and in the presence of SPARC (+SPARC). Addition of SPARC favors acinar differentiation as demonstrated by increased levels of acinar markers ( Cpa and Amy ) and pro-acinar transcription factors ( Rbpjl and Ptf1a ). Expression level of control genes ( Rbpj and E-Cadherin ) are not affected. ( b ) RT-qPCR analysis of acinar and control genes reported to β-actin in pancreatic explants cultured for 3 days in control medium (Ctrl) and in the presence of laminin-α1β1γ1. In the presence of laminin-α1β1γ1, the expression of acinar markers ( Cpa and Amy ) and pro-acinar transcription factors ( Rbpjl and Ptf1a ) is reduced as compared to control explants. Expression level of control genes ( Rbpjl and E-Cadherin ) is not affected. (Mann-Whitney: *p < 0.05). ( c ) Immunofluorescence for the acinar differentiation marker Amylase (green) and the pancreatic epithelium marker (E-Cadherin, red) in explants at 3 days, as indicated. As compared to control explants showing acinar differentiation (Amylase + cells), addition of SPARC stimulates, while laminin-α1β1γ1 decreases the Amylase signal.
Goat Anti Human F Ab 2, supplied by Jackson Immuno, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 93 stars, based on 1 article reviews
goat anti human f ab 2 - by Bioz Stars, 2026-06
93/100 stars
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biotin sp affinipure donkey anti rabbit igg h l  (Jackson Immuno)
96
Jackson Immuno biotin sp affinipure donkey anti rabbit igg h l
<t>SPARC</t> and laminin-α1β1γ1, two proteins abundantly found in EPC-CM, control acinar differentiation. ( a ) RT-qPCR analysis of acinar and control genes reported to β-actin in pancreatic explants cultured for 3 days in control medium (Ctrl) and in the presence of SPARC (+SPARC). Addition of SPARC favors acinar differentiation as demonstrated by increased levels of acinar markers ( Cpa and Amy ) and pro-acinar transcription factors ( Rbpjl and Ptf1a ). Expression level of control genes ( Rbpj and E-Cadherin ) are not affected. ( b ) RT-qPCR analysis of acinar and control genes reported to β-actin in pancreatic explants cultured for 3 days in control medium (Ctrl) and in the presence of laminin-α1β1γ1. In the presence of laminin-α1β1γ1, the expression of acinar markers ( Cpa and Amy ) and pro-acinar transcription factors ( Rbpjl and Ptf1a ) is reduced as compared to control explants. Expression level of control genes ( Rbpjl and E-Cadherin ) is not affected. (Mann-Whitney: *p < 0.05). ( c ) Immunofluorescence for the acinar differentiation marker Amylase (green) and the pancreatic epithelium marker (E-Cadherin, red) in explants at 3 days, as indicated. As compared to control explants showing acinar differentiation (Amylase + cells), addition of SPARC stimulates, while laminin-α1β1γ1 decreases the Amylase signal.
Biotin Sp Affinipure Donkey Anti Rabbit Igg H L, supplied by Jackson Immuno, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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biotin sp affinipure donkey anti rabbit igg h l - by Bioz Stars, 2026-06
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biotinylated donkey anti goat immunoglobulin  (Jackson Immuno)
95
Jackson Immuno biotinylated donkey anti goat immunoglobulin
<t>SPARC</t> and laminin-α1β1γ1, two proteins abundantly found in EPC-CM, control acinar differentiation. ( a ) RT-qPCR analysis of acinar and control genes reported to β-actin in pancreatic explants cultured for 3 days in control medium (Ctrl) and in the presence of SPARC (+SPARC). Addition of SPARC favors acinar differentiation as demonstrated by increased levels of acinar markers ( Cpa and Amy ) and pro-acinar transcription factors ( Rbpjl and Ptf1a ). Expression level of control genes ( Rbpj and E-Cadherin ) are not affected. ( b ) RT-qPCR analysis of acinar and control genes reported to β-actin in pancreatic explants cultured for 3 days in control medium (Ctrl) and in the presence of laminin-α1β1γ1. In the presence of laminin-α1β1γ1, the expression of acinar markers ( Cpa and Amy ) and pro-acinar transcription factors ( Rbpjl and Ptf1a ) is reduced as compared to control explants. Expression level of control genes ( Rbpjl and E-Cadherin ) is not affected. (Mann-Whitney: *p < 0.05). ( c ) Immunofluorescence for the acinar differentiation marker Amylase (green) and the pancreatic epithelium marker (E-Cadherin, red) in explants at 3 days, as indicated. As compared to control explants showing acinar differentiation (Amylase + cells), addition of SPARC stimulates, while laminin-α1β1γ1 decreases the Amylase signal.
Biotinylated Donkey Anti Goat Immunoglobulin, supplied by Jackson Immuno, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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biotinylated donkey anti goat immunoglobulin - by Bioz Stars, 2026-06
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f(ab) 2 fragment specific antibody (jackson immunoresearch laboratories, cat  (Jackson Immuno)
93
Jackson Immuno f(ab) 2 fragment specific antibody (jackson immunoresearch laboratories, cat
<t>SPARC</t> and laminin-α1β1γ1, two proteins abundantly found in EPC-CM, control acinar differentiation. ( a ) RT-qPCR analysis of acinar and control genes reported to β-actin in pancreatic explants cultured for 3 days in control medium (Ctrl) and in the presence of SPARC (+SPARC). Addition of SPARC favors acinar differentiation as demonstrated by increased levels of acinar markers ( Cpa and Amy ) and pro-acinar transcription factors ( Rbpjl and Ptf1a ). Expression level of control genes ( Rbpj and E-Cadherin ) are not affected. ( b ) RT-qPCR analysis of acinar and control genes reported to β-actin in pancreatic explants cultured for 3 days in control medium (Ctrl) and in the presence of laminin-α1β1γ1. In the presence of laminin-α1β1γ1, the expression of acinar markers ( Cpa and Amy ) and pro-acinar transcription factors ( Rbpjl and Ptf1a ) is reduced as compared to control explants. Expression level of control genes ( Rbpjl and E-Cadherin ) is not affected. (Mann-Whitney: *p < 0.05). ( c ) Immunofluorescence for the acinar differentiation marker Amylase (green) and the pancreatic epithelium marker (E-Cadherin, red) in explants at 3 days, as indicated. As compared to control explants showing acinar differentiation (Amylase + cells), addition of SPARC stimulates, while laminin-α1β1γ1 decreases the Amylase signal.
F(ab) 2 Fragment Specific Antibody (Jackson Immunoresearch Laboratories, Cat, supplied by Jackson Immuno, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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f(ab) 2 fragment specific antibody (jackson immunoresearch laboratories, cat - by Bioz Stars, 2026-06
93/100 stars
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fab fragments  (Jackson Immuno)
92
Jackson Immuno fab fragments
<t>SPARC</t> and laminin-α1β1γ1, two proteins abundantly found in EPC-CM, control acinar differentiation. ( a ) RT-qPCR analysis of acinar and control genes reported to β-actin in pancreatic explants cultured for 3 days in control medium (Ctrl) and in the presence of SPARC (+SPARC). Addition of SPARC favors acinar differentiation as demonstrated by increased levels of acinar markers ( Cpa and Amy ) and pro-acinar transcription factors ( Rbpjl and Ptf1a ). Expression level of control genes ( Rbpj and E-Cadherin ) are not affected. ( b ) RT-qPCR analysis of acinar and control genes reported to β-actin in pancreatic explants cultured for 3 days in control medium (Ctrl) and in the presence of laminin-α1β1γ1. In the presence of laminin-α1β1γ1, the expression of acinar markers ( Cpa and Amy ) and pro-acinar transcription factors ( Rbpjl and Ptf1a ) is reduced as compared to control explants. Expression level of control genes ( Rbpjl and E-Cadherin ) is not affected. (Mann-Whitney: *p < 0.05). ( c ) Immunofluorescence for the acinar differentiation marker Amylase (green) and the pancreatic epithelium marker (E-Cadherin, red) in explants at 3 days, as indicated. As compared to control explants showing acinar differentiation (Amylase + cells), addition of SPARC stimulates, while laminin-α1β1γ1 decreases the Amylase signal.
Fab Fragments, supplied by Jackson Immuno, used in various techniques. Bioz Stars score: 92/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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fab fragments - by Bioz Stars, 2026-06
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Image Search Results


SPARC and laminin-α1β1γ1, two proteins abundantly found in EPC-CM, control acinar differentiation. ( a ) RT-qPCR analysis of acinar and control genes reported to β-actin in pancreatic explants cultured for 3 days in control medium (Ctrl) and in the presence of SPARC (+SPARC). Addition of SPARC favors acinar differentiation as demonstrated by increased levels of acinar markers ( Cpa and Amy ) and pro-acinar transcription factors ( Rbpjl and Ptf1a ). Expression level of control genes ( Rbpj and E-Cadherin ) are not affected. ( b ) RT-qPCR analysis of acinar and control genes reported to β-actin in pancreatic explants cultured for 3 days in control medium (Ctrl) and in the presence of laminin-α1β1γ1. In the presence of laminin-α1β1γ1, the expression of acinar markers ( Cpa and Amy ) and pro-acinar transcription factors ( Rbpjl and Ptf1a ) is reduced as compared to control explants. Expression level of control genes ( Rbpjl and E-Cadherin ) is not affected. (Mann-Whitney: *p < 0.05). ( c ) Immunofluorescence for the acinar differentiation marker Amylase (green) and the pancreatic epithelium marker (E-Cadherin, red) in explants at 3 days, as indicated. As compared to control explants showing acinar differentiation (Amylase + cells), addition of SPARC stimulates, while laminin-α1β1γ1 decreases the Amylase signal.

Journal: Scientific Reports

Article Title: Pancreatic acinar differentiation is guided by differential laminin deposition

doi: 10.1038/s41598-019-39077-6

Figure Lengend Snippet: SPARC and laminin-α1β1γ1, two proteins abundantly found in EPC-CM, control acinar differentiation. ( a ) RT-qPCR analysis of acinar and control genes reported to β-actin in pancreatic explants cultured for 3 days in control medium (Ctrl) and in the presence of SPARC (+SPARC). Addition of SPARC favors acinar differentiation as demonstrated by increased levels of acinar markers ( Cpa and Amy ) and pro-acinar transcription factors ( Rbpjl and Ptf1a ). Expression level of control genes ( Rbpj and E-Cadherin ) are not affected. ( b ) RT-qPCR analysis of acinar and control genes reported to β-actin in pancreatic explants cultured for 3 days in control medium (Ctrl) and in the presence of laminin-α1β1γ1. In the presence of laminin-α1β1γ1, the expression of acinar markers ( Cpa and Amy ) and pro-acinar transcription factors ( Rbpjl and Ptf1a ) is reduced as compared to control explants. Expression level of control genes ( Rbpjl and E-Cadherin ) is not affected. (Mann-Whitney: *p < 0.05). ( c ) Immunofluorescence for the acinar differentiation marker Amylase (green) and the pancreatic epithelium marker (E-Cadherin, red) in explants at 3 days, as indicated. As compared to control explants showing acinar differentiation (Amylase + cells), addition of SPARC stimulates, while laminin-α1β1γ1 decreases the Amylase signal.

Article Snippet: Medium was supplemented with either 1 μg/ml recombinant mouse SPARC (R&D Systems), 2.5 μg/ml purified laminin-α1β1γ1 (gift from T. Sasaki), 3 μM of VEGFR2 inhibitor (SU5416, VWR), or vehicles.

Techniques: Control, Quantitative RT-PCR, Cell Culture, Expressing, MANN-WHITNEY, Immunofluorescence, Marker