smc media Search Results


muscle cell basal medium cell applications  (Cell Applications Inc)
96
Cell Applications Inc muscle cell basal medium cell applications
Muscle Cell Basal Medium Cell Applications, supplied by Cell Applications Inc, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/muscle cell basal medium cell applications/product/Cell Applications Inc
Average 96 stars, based on 1 article reviews
muscle cell basal medium cell applications - by Bioz Stars, 2026-03
96/100 stars
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smc maintaining media  (Lonza)
90
Lonza smc maintaining media
( a ) SMCs within advanced atherosclerotic lesion specimens were identified based on PLA detection of the <t>SMC</t> specific stable epigenetic signature H3K4dime on the MYH11 . MYH11 H3K4dime PLA + cells exhibit a punctate red dot within the nucleus while the non-nuclear amorphous red staining is autofluorescence or non-specific background. ( a ) Samples were also immuno-stained for CD68 (green), and DAPI (blue). Results showed three distinct cell populations highlighted in enlarged panels to the right and indicated with white arrows: (i) MYH11 H3K4dime PLA + SMCs that are CD68 − , (ii) MYH11 H3K4dime PLA − CD68 + (HSC-derived Mϕs), and (iii) H3K4dime MYH11 H3K4dime PLA + CD68 + SMC-derived Mϕ-like cells. Scale bar = 100 μm. ( b ) Shoulder regions within plaques [stained with DAPI (blue), ACTA2 (green), PLA (red), and CD68 (cyan)] exhibited a high incidence of SMC-derived Mϕ-like cells ( MYH11 H3K4dime PLA + CD68 + ) (yellow arrows) and several phenotypically modulated SMCs negative for CD68 ( MYH11 H3K4dime PLA + ACTA2 − CD68 − ) (white arrows). Scale bar = 50 μm. ( c ) Quantitative analysis of SMC-derived Mϕ-like cells within <t>human</t> <t>coronary</t> lesions based on MYH11 H3K4dime ISH-PLA +/− adjustment for the efficiency of PLA . Error bars = S.E.M. for 12 independent samples of human atherosclerosis in the right coronary artery. ( d ) Combined epigenetic SMC and genetic HSC lineage tracing analyses of cross gender human heart transplant samples. Coronary artery specimens from a male patient who received a female heart were processed for MYH11 H3K4dime PLA (red), Y-chromosome FISH (green), and CD68 staining (yellow). Results show cells that were MYH11 H3K4dime PLA + Y-chromosome − and CD68 + (yellow arrows) reflecting a SMC-derived Mϕ-like cell not of hematopoietic origin (top). In contrast, Mϕs of hematopoietic origin are MYH11 H3K4dime PLA − Y-chromosome + CD68 + (red arrows) (bottom). Scale bar = 50 μm.
Smc Maintaining Media, supplied by Lonza, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/smc maintaining media/product/Lonza
Average 90 stars, based on 1 article reviews
smc maintaining media - by Bioz Stars, 2026-03
90/100 stars
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smc basic media  (Lonza)
90
Lonza smc basic media
( a ) SMCs within advanced atherosclerotic lesion specimens were identified based on PLA detection of the <t>SMC</t> specific stable epigenetic signature H3K4dime on the MYH11 . MYH11 H3K4dime PLA + cells exhibit a punctate red dot within the nucleus while the non-nuclear amorphous red staining is autofluorescence or non-specific background. ( a ) Samples were also immuno-stained for CD68 (green), and DAPI (blue). Results showed three distinct cell populations highlighted in enlarged panels to the right and indicated with white arrows: (i) MYH11 H3K4dime PLA + SMCs that are CD68 − , (ii) MYH11 H3K4dime PLA − CD68 + (HSC-derived Mϕs), and (iii) H3K4dime MYH11 H3K4dime PLA + CD68 + SMC-derived Mϕ-like cells. Scale bar = 100 μm. ( b ) Shoulder regions within plaques [stained with DAPI (blue), ACTA2 (green), PLA (red), and CD68 (cyan)] exhibited a high incidence of SMC-derived Mϕ-like cells ( MYH11 H3K4dime PLA + CD68 + ) (yellow arrows) and several phenotypically modulated SMCs negative for CD68 ( MYH11 H3K4dime PLA + ACTA2 − CD68 − ) (white arrows). Scale bar = 50 μm. ( c ) Quantitative analysis of SMC-derived Mϕ-like cells within <t>human</t> <t>coronary</t> lesions based on MYH11 H3K4dime ISH-PLA +/− adjustment for the efficiency of PLA . Error bars = S.E.M. for 12 independent samples of human atherosclerosis in the right coronary artery. ( d ) Combined epigenetic SMC and genetic HSC lineage tracing analyses of cross gender human heart transplant samples. Coronary artery specimens from a male patient who received a female heart were processed for MYH11 H3K4dime PLA (red), Y-chromosome FISH (green), and CD68 staining (yellow). Results show cells that were MYH11 H3K4dime PLA + Y-chromosome − and CD68 + (yellow arrows) reflecting a SMC-derived Mϕ-like cell not of hematopoietic origin (top). In contrast, Mϕs of hematopoietic origin are MYH11 H3K4dime PLA − Y-chromosome + CD68 + (red arrows) (bottom). Scale bar = 50 μm.
Smc Basic Media, supplied by Lonza, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/smc basic media/product/Lonza
Average 90 stars, based on 1 article reviews
smc basic media - by Bioz Stars, 2026-03
90/100 stars
  Buy from Supplier
commercial smc media (lonza)  (Lonza)
90
Lonza commercial smc media (lonza)
( a ) SMCs within advanced atherosclerotic lesion specimens were identified based on PLA detection of the <t>SMC</t> specific stable epigenetic signature H3K4dime on the MYH11 . MYH11 H3K4dime PLA + cells exhibit a punctate red dot within the nucleus while the non-nuclear amorphous red staining is autofluorescence or non-specific background. ( a ) Samples were also immuno-stained for CD68 (green), and DAPI (blue). Results showed three distinct cell populations highlighted in enlarged panels to the right and indicated with white arrows: (i) MYH11 H3K4dime PLA + SMCs that are CD68 − , (ii) MYH11 H3K4dime PLA − CD68 + (HSC-derived Mϕs), and (iii) H3K4dime MYH11 H3K4dime PLA + CD68 + SMC-derived Mϕ-like cells. Scale bar = 100 μm. ( b ) Shoulder regions within plaques [stained with DAPI (blue), ACTA2 (green), PLA (red), and CD68 (cyan)] exhibited a high incidence of SMC-derived Mϕ-like cells ( MYH11 H3K4dime PLA + CD68 + ) (yellow arrows) and several phenotypically modulated SMCs negative for CD68 ( MYH11 H3K4dime PLA + ACTA2 − CD68 − ) (white arrows). Scale bar = 50 μm. ( c ) Quantitative analysis of SMC-derived Mϕ-like cells within <t>human</t> <t>coronary</t> lesions based on MYH11 H3K4dime ISH-PLA +/− adjustment for the efficiency of PLA . Error bars = S.E.M. for 12 independent samples of human atherosclerosis in the right coronary artery. ( d ) Combined epigenetic SMC and genetic HSC lineage tracing analyses of cross gender human heart transplant samples. Coronary artery specimens from a male patient who received a female heart were processed for MYH11 H3K4dime PLA (red), Y-chromosome FISH (green), and CD68 staining (yellow). Results show cells that were MYH11 H3K4dime PLA + Y-chromosome − and CD68 + (yellow arrows) reflecting a SMC-derived Mϕ-like cell not of hematopoietic origin (top). In contrast, Mϕs of hematopoietic origin are MYH11 H3K4dime PLA − Y-chromosome + CD68 + (red arrows) (bottom). Scale bar = 50 μm.
Commercial Smc Media (Lonza), supplied by Lonza, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/commercial smc media (lonza)/product/Lonza
Average 90 stars, based on 1 article reviews
commercial smc media (lonza) - by Bioz Stars, 2026-03
90/100 stars
  Buy from Supplier
smc growing media sg2  (Kurabo industries)
90
Kurabo industries smc growing media sg2
( a ) SMCs within advanced atherosclerotic lesion specimens were identified based on PLA detection of the <t>SMC</t> specific stable epigenetic signature H3K4dime on the MYH11 . MYH11 H3K4dime PLA + cells exhibit a punctate red dot within the nucleus while the non-nuclear amorphous red staining is autofluorescence or non-specific background. ( a ) Samples were also immuno-stained for CD68 (green), and DAPI (blue). Results showed three distinct cell populations highlighted in enlarged panels to the right and indicated with white arrows: (i) MYH11 H3K4dime PLA + SMCs that are CD68 − , (ii) MYH11 H3K4dime PLA − CD68 + (HSC-derived Mϕs), and (iii) H3K4dime MYH11 H3K4dime PLA + CD68 + SMC-derived Mϕ-like cells. Scale bar = 100 μm. ( b ) Shoulder regions within plaques [stained with DAPI (blue), ACTA2 (green), PLA (red), and CD68 (cyan)] exhibited a high incidence of SMC-derived Mϕ-like cells ( MYH11 H3K4dime PLA + CD68 + ) (yellow arrows) and several phenotypically modulated SMCs negative for CD68 ( MYH11 H3K4dime PLA + ACTA2 − CD68 − ) (white arrows). Scale bar = 50 μm. ( c ) Quantitative analysis of SMC-derived Mϕ-like cells within <t>human</t> <t>coronary</t> lesions based on MYH11 H3K4dime ISH-PLA +/− adjustment for the efficiency of PLA . Error bars = S.E.M. for 12 independent samples of human atherosclerosis in the right coronary artery. ( d ) Combined epigenetic SMC and genetic HSC lineage tracing analyses of cross gender human heart transplant samples. Coronary artery specimens from a male patient who received a female heart were processed for MYH11 H3K4dime PLA (red), Y-chromosome FISH (green), and CD68 staining (yellow). Results show cells that were MYH11 H3K4dime PLA + Y-chromosome − and CD68 + (yellow arrows) reflecting a SMC-derived Mϕ-like cell not of hematopoietic origin (top). In contrast, Mϕs of hematopoietic origin are MYH11 H3K4dime PLA − Y-chromosome + CD68 + (red arrows) (bottom). Scale bar = 50 μm.
Smc Growing Media Sg2, supplied by Kurabo industries, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/smc growing media sg2/product/Kurabo industries
Average 90 stars, based on 1 article reviews
smc growing media sg2 - by Bioz Stars, 2026-03
90/100 stars
  Buy from Supplier
smc growth media  (BioWhittaker Molecular Applications)
90
BioWhittaker Molecular Applications smc growth media
( a ) SMCs within advanced atherosclerotic lesion specimens were identified based on PLA detection of the <t>SMC</t> specific stable epigenetic signature H3K4dime on the MYH11 . MYH11 H3K4dime PLA + cells exhibit a punctate red dot within the nucleus while the non-nuclear amorphous red staining is autofluorescence or non-specific background. ( a ) Samples were also immuno-stained for CD68 (green), and DAPI (blue). Results showed three distinct cell populations highlighted in enlarged panels to the right and indicated with white arrows: (i) MYH11 H3K4dime PLA + SMCs that are CD68 − , (ii) MYH11 H3K4dime PLA − CD68 + (HSC-derived Mϕs), and (iii) H3K4dime MYH11 H3K4dime PLA + CD68 + SMC-derived Mϕ-like cells. Scale bar = 100 μm. ( b ) Shoulder regions within plaques [stained with DAPI (blue), ACTA2 (green), PLA (red), and CD68 (cyan)] exhibited a high incidence of SMC-derived Mϕ-like cells ( MYH11 H3K4dime PLA + CD68 + ) (yellow arrows) and several phenotypically modulated SMCs negative for CD68 ( MYH11 H3K4dime PLA + ACTA2 − CD68 − ) (white arrows). Scale bar = 50 μm. ( c ) Quantitative analysis of SMC-derived Mϕ-like cells within <t>human</t> <t>coronary</t> lesions based on MYH11 H3K4dime ISH-PLA +/− adjustment for the efficiency of PLA . Error bars = S.E.M. for 12 independent samples of human atherosclerosis in the right coronary artery. ( d ) Combined epigenetic SMC and genetic HSC lineage tracing analyses of cross gender human heart transplant samples. Coronary artery specimens from a male patient who received a female heart were processed for MYH11 H3K4dime PLA (red), Y-chromosome FISH (green), and CD68 staining (yellow). Results show cells that were MYH11 H3K4dime PLA + Y-chromosome − and CD68 + (yellow arrows) reflecting a SMC-derived Mϕ-like cell not of hematopoietic origin (top). In contrast, Mϕs of hematopoietic origin are MYH11 H3K4dime PLA − Y-chromosome + CD68 + (red arrows) (bottom). Scale bar = 50 μm.
Smc Growth Media, supplied by BioWhittaker Molecular Applications, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/smc growth media/product/BioWhittaker Molecular Applications
Average 90 stars, based on 1 article reviews
smc growth media - by Bioz Stars, 2026-03
90/100 stars
  Buy from Supplier

Image Search Results


( a ) SMCs within advanced atherosclerotic lesion specimens were identified based on PLA detection of the SMC specific stable epigenetic signature H3K4dime on the MYH11 . MYH11 H3K4dime PLA + cells exhibit a punctate red dot within the nucleus while the non-nuclear amorphous red staining is autofluorescence or non-specific background. ( a ) Samples were also immuno-stained for CD68 (green), and DAPI (blue). Results showed three distinct cell populations highlighted in enlarged panels to the right and indicated with white arrows: (i) MYH11 H3K4dime PLA + SMCs that are CD68 − , (ii) MYH11 H3K4dime PLA − CD68 + (HSC-derived Mϕs), and (iii) H3K4dime MYH11 H3K4dime PLA + CD68 + SMC-derived Mϕ-like cells. Scale bar = 100 μm. ( b ) Shoulder regions within plaques [stained with DAPI (blue), ACTA2 (green), PLA (red), and CD68 (cyan)] exhibited a high incidence of SMC-derived Mϕ-like cells ( MYH11 H3K4dime PLA + CD68 + ) (yellow arrows) and several phenotypically modulated SMCs negative for CD68 ( MYH11 H3K4dime PLA + ACTA2 − CD68 − ) (white arrows). Scale bar = 50 μm. ( c ) Quantitative analysis of SMC-derived Mϕ-like cells within human coronary lesions based on MYH11 H3K4dime ISH-PLA +/− adjustment for the efficiency of PLA . Error bars = S.E.M. for 12 independent samples of human atherosclerosis in the right coronary artery. ( d ) Combined epigenetic SMC and genetic HSC lineage tracing analyses of cross gender human heart transplant samples. Coronary artery specimens from a male patient who received a female heart were processed for MYH11 H3K4dime PLA (red), Y-chromosome FISH (green), and CD68 staining (yellow). Results show cells that were MYH11 H3K4dime PLA + Y-chromosome − and CD68 + (yellow arrows) reflecting a SMC-derived Mϕ-like cell not of hematopoietic origin (top). In contrast, Mϕs of hematopoietic origin are MYH11 H3K4dime PLA − Y-chromosome + CD68 + (red arrows) (bottom). Scale bar = 50 μm.

Journal: Nature medicine

Article Title: KLF4 Dependent Phenotypic Modulation of SMCs Plays a Key Role in Atherosclerotic Plaque Pathogenesis

doi: 10.1038/nm.3866

Figure Lengend Snippet: ( a ) SMCs within advanced atherosclerotic lesion specimens were identified based on PLA detection of the SMC specific stable epigenetic signature H3K4dime on the MYH11 . MYH11 H3K4dime PLA + cells exhibit a punctate red dot within the nucleus while the non-nuclear amorphous red staining is autofluorescence or non-specific background. ( a ) Samples were also immuno-stained for CD68 (green), and DAPI (blue). Results showed three distinct cell populations highlighted in enlarged panels to the right and indicated with white arrows: (i) MYH11 H3K4dime PLA + SMCs that are CD68 − , (ii) MYH11 H3K4dime PLA − CD68 + (HSC-derived Mϕs), and (iii) H3K4dime MYH11 H3K4dime PLA + CD68 + SMC-derived Mϕ-like cells. Scale bar = 100 μm. ( b ) Shoulder regions within plaques [stained with DAPI (blue), ACTA2 (green), PLA (red), and CD68 (cyan)] exhibited a high incidence of SMC-derived Mϕ-like cells ( MYH11 H3K4dime PLA + CD68 + ) (yellow arrows) and several phenotypically modulated SMCs negative for CD68 ( MYH11 H3K4dime PLA + ACTA2 − CD68 − ) (white arrows). Scale bar = 50 μm. ( c ) Quantitative analysis of SMC-derived Mϕ-like cells within human coronary lesions based on MYH11 H3K4dime ISH-PLA +/− adjustment for the efficiency of PLA . Error bars = S.E.M. for 12 independent samples of human atherosclerosis in the right coronary artery. ( d ) Combined epigenetic SMC and genetic HSC lineage tracing analyses of cross gender human heart transplant samples. Coronary artery specimens from a male patient who received a female heart were processed for MYH11 H3K4dime PLA (red), Y-chromosome FISH (green), and CD68 staining (yellow). Results show cells that were MYH11 H3K4dime PLA + Y-chromosome − and CD68 + (yellow arrows) reflecting a SMC-derived Mϕ-like cell not of hematopoietic origin (top). In contrast, Mϕs of hematopoietic origin are MYH11 H3K4dime PLA − Y-chromosome + CD68 + (red arrows) (bottom). Scale bar = 50 μm.

Article Snippet: Human coronary SMC were purchased from Lonza and cultured in SMC maintaining media (Lonza).

Techniques: Staining, Derivative Assay