ska-31 Search Results


91
Alomone Labs ska
Ska, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 91/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/ska-31/SKA-31/pmc06520228-111-18-22
Average 91 stars, based on 1 article reviews
ska - by Bioz Stars, 2026-09
91/100 stars
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94
MedChemExpress ska 31
TPEN induced vasorelaxation of the second-order branch of mice mesenteric arteries via EDH mechanisms predominantly. (A) Summarized data shows TPEN-induced CRC, R max , AUC and EC 50 of the second-order branch of mice mesenteric arteries pre-constricted with NE (5 μM, n = 6) or KCl (80 mM, n = 6). (B) Summarized data shows TPEN-induced CRC, R max , AUC and EC 50 of the second-order branch of mice mesenteric arteries with 100 μM L-NNA plus 10 μM INDO (n = 6), L-NNA + INDO (&) + 0.3 μM <t>SKA-31(n</t> = 6), or L-NNA + INDO (&) + 3 μM apamin (Apa) + 30 μM TRAM-34 (TRAM, n = 6). (C) Summarized data shows TPEN-induced CRC, R max , AUC and EC 50 of the second-order branch of mice mesenteric arteries with L-NNA + INDO (n = 6), or L-NNA + INDO (&) + 10 μM SN-6 (n = 6), or L-NNA + INDO (&) + 100 μM ouabain (n = 6). Data were expressed as a percentage of NE-induced vasoconstriction and shown as means ± SEM. ** P < 0.01, *** P < 0.001, **** P < 0.0001 and ns: no significance.
Ska 31, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/ska-31/SKA-31/pmc11301249-103-3-17
Average 94 stars, based on 1 article reviews
ska 31 - by Bioz Stars, 2026-09
94/100 stars
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93
Tocris ska 31
TPEN induced vasorelaxation of the second-order branch of mice mesenteric arteries via EDH mechanisms predominantly. (A) Summarized data shows TPEN-induced CRC, R max , AUC and EC 50 of the second-order branch of mice mesenteric arteries pre-constricted with NE (5 μM, n = 6) or KCl (80 mM, n = 6). (B) Summarized data shows TPEN-induced CRC, R max , AUC and EC 50 of the second-order branch of mice mesenteric arteries with 100 μM L-NNA plus 10 μM INDO (n = 6), L-NNA + INDO (&) + 0.3 μM <t>SKA-31(n</t> = 6), or L-NNA + INDO (&) + 3 μM apamin (Apa) + 30 μM TRAM-34 (TRAM, n = 6). (C) Summarized data shows TPEN-induced CRC, R max , AUC and EC 50 of the second-order branch of mice mesenteric arteries with L-NNA + INDO (n = 6), or L-NNA + INDO (&) + 10 μM SN-6 (n = 6), or L-NNA + INDO (&) + 100 μM ouabain (n = 6). Data were expressed as a percentage of NE-induced vasoconstriction and shown as means ± SEM. ** P < 0.01, *** P < 0.001, **** P < 0.0001 and ns: no significance.
Ska 31, supplied by Tocris, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/ska-31/SKA+31/10__1161_slash_circresaha__111__262592-416-2-3
Average 93 stars, based on 1 article reviews
ska 31 - by Bioz Stars, 2026-09
93/100 stars
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93
Tocris ska31
TPEN induced vasorelaxation of the second-order branch of mice mesenteric arteries via EDH mechanisms predominantly. (A) Summarized data shows TPEN-induced CRC, R max , AUC and EC 50 of the second-order branch of mice mesenteric arteries pre-constricted with NE (5 μM, n = 6) or KCl (80 mM, n = 6). (B) Summarized data shows TPEN-induced CRC, R max , AUC and EC 50 of the second-order branch of mice mesenteric arteries with 100 μM L-NNA plus 10 μM INDO (n = 6), L-NNA + INDO (&) + 0.3 μM <t>SKA-31(n</t> = 6), or L-NNA + INDO (&) + 3 μM apamin (Apa) + 30 μM TRAM-34 (TRAM, n = 6). (C) Summarized data shows TPEN-induced CRC, R max , AUC and EC 50 of the second-order branch of mice mesenteric arteries with L-NNA + INDO (n = 6), or L-NNA + INDO (&) + 10 μM SN-6 (n = 6), or L-NNA + INDO (&) + 100 μM ouabain (n = 6). Data were expressed as a percentage of NE-induced vasoconstriction and shown as means ± SEM. ** P < 0.01, *** P < 0.001, **** P < 0.0001 and ns: no significance.
Ska31, supplied by Tocris, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/ska-31/SKA+31/pm22242975-52-5-16
Average 93 stars, based on 1 article reviews
ska31 - by Bioz Stars, 2026-09
93/100 stars
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90
Wulff labs ska-31
TPEN induced vasorelaxation of the second-order branch of mice mesenteric arteries via EDH mechanisms predominantly. (A) Summarized data shows TPEN-induced CRC, R max , AUC and EC 50 of the second-order branch of mice mesenteric arteries pre-constricted with NE (5 μM, n = 6) or KCl (80 mM, n = 6). (B) Summarized data shows TPEN-induced CRC, R max , AUC and EC 50 of the second-order branch of mice mesenteric arteries with 100 μM L-NNA plus 10 μM INDO (n = 6), L-NNA + INDO (&) + 0.3 μM <t>SKA-31(n</t> = 6), or L-NNA + INDO (&) + 3 μM apamin (Apa) + 30 μM TRAM-34 (TRAM, n = 6). (C) Summarized data shows TPEN-induced CRC, R max , AUC and EC 50 of the second-order branch of mice mesenteric arteries with L-NNA + INDO (n = 6), or L-NNA + INDO (&) + 10 μM SN-6 (n = 6), or L-NNA + INDO (&) + 100 μM ouabain (n = 6). Data were expressed as a percentage of NE-induced vasoconstriction and shown as means ± SEM. ** P < 0.01, *** P < 0.001, **** P < 0.0001 and ns: no significance.
Ska 31, supplied by Wulff labs, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/ska-31/ska+31/pmc02635097-410-17-12
Average 90 stars, based on 1 article reviews
ska-31 - by Bioz Stars, 2026-09
90/100 stars
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86
Selleck Chemicals erk1 2 pathway
TPEN induced vasorelaxation of the second-order branch of mice mesenteric arteries via EDH mechanisms predominantly. (A) Summarized data shows TPEN-induced CRC, R max , AUC and EC 50 of the second-order branch of mice mesenteric arteries pre-constricted with NE (5 μM, n = 6) or KCl (80 mM, n = 6). (B) Summarized data shows TPEN-induced CRC, R max , AUC and EC 50 of the second-order branch of mice mesenteric arteries with 100 μM L-NNA plus 10 μM INDO (n = 6), L-NNA + INDO (&) + 0.3 μM <t>SKA-31(n</t> = 6), or L-NNA + INDO (&) + 3 μM apamin (Apa) + 30 μM TRAM-34 (TRAM, n = 6). (C) Summarized data shows TPEN-induced CRC, R max , AUC and EC 50 of the second-order branch of mice mesenteric arteries with L-NNA + INDO (n = 6), or L-NNA + INDO (&) + 10 μM SN-6 (n = 6), or L-NNA + INDO (&) + 100 μM ouabain (n = 6). Data were expressed as a percentage of NE-induced vasoconstriction and shown as means ± SEM. ** P < 0.01, *** P < 0.001, **** P < 0.0001 and ns: no significance.
Erk1 2 Pathway, supplied by Selleck Chemicals, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/ska-31/SKA-31/pm27592222-44-3-7
Average 86 stars, based on 1 article reviews
erk1 2 pathway - by Bioz Stars, 2026-09
86/100 stars
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90
CEREP Inc ska-31
TPEN induced vasorelaxation of the second-order branch of mice mesenteric arteries via EDH mechanisms predominantly. (A) Summarized data shows TPEN-induced CRC, R max , AUC and EC 50 of the second-order branch of mice mesenteric arteries pre-constricted with NE (5 μM, n = 6) or KCl (80 mM, n = 6). (B) Summarized data shows TPEN-induced CRC, R max , AUC and EC 50 of the second-order branch of mice mesenteric arteries with 100 μM L-NNA plus 10 μM INDO (n = 6), L-NNA + INDO (&) + 0.3 μM <t>SKA-31(n</t> = 6), or L-NNA + INDO (&) + 3 μM apamin (Apa) + 30 μM TRAM-34 (TRAM, n = 6). (C) Summarized data shows TPEN-induced CRC, R max , AUC and EC 50 of the second-order branch of mice mesenteric arteries with L-NNA + INDO (n = 6), or L-NNA + INDO (&) + 10 μM SN-6 (n = 6), or L-NNA + INDO (&) + 100 μM ouabain (n = 6). Data were expressed as a percentage of NE-induced vasoconstriction and shown as means ± SEM. ** P < 0.01, *** P < 0.001, **** P < 0.0001 and ns: no significance.
Ska 31, supplied by CEREP Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/ska-31/ska+31/pm24903240-72-5-13
Average 90 stars, based on 1 article reviews
ska-31 - by Bioz Stars, 2026-09
90/100 stars
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N/A
KCa3.1 and KCa2 channel activator
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N/A
SKA 31 is a KCa3.1 and KCa2 channel activator (EC50 = 260, 2900, 2900 nM for KCa3.1, KCa2.1 and KCa2.2, respectively). SKA 31b has been shown to potentiate acetylcholine-induced EDHF-type dilations of mouse carotid arteries
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N/A
SKA 31(CAT: I010803) is a chemical compound that acts as a potent and selective activator of small and intermediate conductance calcium-activated potassium (SK/IK) channels. It enhances the opening of these channels, resulting in the efflux
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N/A
SKA-31 is a potent potassium channel activator with EC50s of 260 nM, 1.9 μM, 2.9 μM, and 2.9 μM for KCa3.1, KCa2.2, KCa2.1 and KCa2.3, respectively. SKA-31 potentiates endothelium-derived hyperpolarizing factor response and lowers blood
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Image Search Results


TPEN induced vasorelaxation of the second-order branch of mice mesenteric arteries via EDH mechanisms predominantly. (A) Summarized data shows TPEN-induced CRC, R max , AUC and EC 50 of the second-order branch of mice mesenteric arteries pre-constricted with NE (5 μM, n = 6) or KCl (80 mM, n = 6). (B) Summarized data shows TPEN-induced CRC, R max , AUC and EC 50 of the second-order branch of mice mesenteric arteries with 100 μM L-NNA plus 10 μM INDO (n = 6), L-NNA + INDO (&) + 0.3 μM SKA-31(n = 6), or L-NNA + INDO (&) + 3 μM apamin (Apa) + 30 μM TRAM-34 (TRAM, n = 6). (C) Summarized data shows TPEN-induced CRC, R max , AUC and EC 50 of the second-order branch of mice mesenteric arteries with L-NNA + INDO (n = 6), or L-NNA + INDO (&) + 10 μM SN-6 (n = 6), or L-NNA + INDO (&) + 100 μM ouabain (n = 6). Data were expressed as a percentage of NE-induced vasoconstriction and shown as means ± SEM. ** P < 0.01, *** P < 0.001, **** P < 0.0001 and ns: no significance.

Journal: Heliyon

Article Title: N,N,N′,N′-Tetrakis(2-pyridylmethyl)ethylenediamine induces endothelium-dependent hyperpolarization-mediated vasorelaxation via store-operated calcium entry mechanism in healthy and intestinal inflammatory mice

doi: 10.1016/j.heliyon.2024.e33994

Figure Lengend Snippet: TPEN induced vasorelaxation of the second-order branch of mice mesenteric arteries via EDH mechanisms predominantly. (A) Summarized data shows TPEN-induced CRC, R max , AUC and EC 50 of the second-order branch of mice mesenteric arteries pre-constricted with NE (5 μM, n = 6) or KCl (80 mM, n = 6). (B) Summarized data shows TPEN-induced CRC, R max , AUC and EC 50 of the second-order branch of mice mesenteric arteries with 100 μM L-NNA plus 10 μM INDO (n = 6), L-NNA + INDO (&) + 0.3 μM SKA-31(n = 6), or L-NNA + INDO (&) + 3 μM apamin (Apa) + 30 μM TRAM-34 (TRAM, n = 6). (C) Summarized data shows TPEN-induced CRC, R max , AUC and EC 50 of the second-order branch of mice mesenteric arteries with L-NNA + INDO (n = 6), or L-NNA + INDO (&) + 10 μM SN-6 (n = 6), or L-NNA + INDO (&) + 100 μM ouabain (n = 6). Data were expressed as a percentage of NE-induced vasoconstriction and shown as means ± SEM. ** P < 0.01, *** P < 0.001, **** P < 0.0001 and ns: no significance.

Article Snippet: TPEN, TRAM-34, apamin, SKA-31, SN-6, ouabain, GSK-7975 A, SKF96365, ML-9, and Brefeldin A (BFA) were supplied by MedChemExpress (MCE), headquartered in New Jersey, USA.

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