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Image Search Results
Journal: Cell reports
Article Title: APP-Mediated Signaling Prevents Memory Decline in Alzheimer’s Disease Mouse Model
doi: 10.1016/j.celrep.2019.03.087
Figure Lengend Snippet: KEY RESOURCES TABLE
Article Snippet: REAGENT or RESOURCE SOURCE IDENTIFIER Antibodies Rabbit polyclonal anti-APP-CTM1 Dr. Gopal Thinakaran ( Vetrivel et al., 2009 ) N/A Rabbit polyclonal anti-APP-CT11 Dr. Gopal Thinakaran ( Vetrivel et al., 2009 ) N/A Rabbit polyclonal anti-APP-NT452 Dr. Gopal Thinakaran ( Vetrivel et al., 2009 ) N/A Mouse monoclonal anti-N-terminal Aβ antibody (clone 3D6) Dr. Dale Schenk (Elan Corporation PLC2) ( Andrew et al. 2017 ) N/A Mouse monoclonal anti-flag (clone M2) Sigma Aldrich Cat#F3165; RRID:AB_259529 Rabbit polyclonal MAP2 Sigma-Aldrich Cat#M3696; RRID:AB_1840999 Mouse monoclonal GAPDH Abeam Cat#ab8245; RRID:AB_2107448 Mouse monoclonal anti-HA (clone 6E2) Cell Signaling Cat#2367; RRID:AB_10691311 Goat anti-mouse Alexa 488 Invitrogen Cat#A-11029; RRID:AB_2534088 Goat anti-mouse Alexa 555 Invitrogen Cat#A-21424; RRID:AB_141780 Goat anti-rabbit Alexa 555 Invitrogen Cat#A-21429; RRID:AB_141761 IRDye 680LT donkey anti-mouse LI-COR Biosciences Cat# 926–68022; RRID:AB_10715072 IRDye 680 donkey anti-rabbit LI-COR Biosciences Cat# 926–32223; RRID:AB_621845 IRDye 800CW donkey anti-mouse LI-COR Biosciences Cat# 926–32212; RRID:AB_621847 IRDye 800CW goat anti-rabbit LI-COR Biosciences Cat#827–08365; RRID:AB_01796098 Aβ end-specific sandwich ELISA using end-specific antibodies (2.1.3: Aβ 42; 13.1.1: Aβ 40 for capture) and Ab5-HRP (pan Aβ) for detection Dr. Todd Golde ( Chakrabarty et al., 2015 ) N/A Mouse monoclonal Aβ anti-B608 for capture and anti-B436 for detection of sandwich ELISA Dr. Steven Wagner ( Vetrivel et al., 2009 ) N/A Bacterial and Virus Strains rAAV2/8 caps id packaging Dr. Todd Golde ( Chakrabarty et al., 2013 ) N/A Chemicals, Peptides, and Recombinant Proteins γ-secretase inhibitor Compound E Dr. Todd Golde Mayo Clinic core facility ( Seiffert et al., 2000 ) N/A Cis-N-(2-phenylcyclopentyl) azacyclotridec-1-en-2-amine (MDL-12,330A) Enzo Life Science Cat#
Techniques: Sandwich ELISA, Virus, Recombinant, Protease Inhibitor, Plasmid Preparation, Expressing, Mutagenesis, Transgenic Assay, Knock-Out, Software