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Sony
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Asahi Kasei Corporation
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Verity Software House
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Becton Dickinson
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SH Scientific Co Ltd
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Tree Star Inc
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Johns Hopkins HealthCare
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Allakos Inc
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MolGen LLC
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Courage Khazaka electronic Gmbh
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Sony Biotechnology
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Image Search Results
Journal: Nutrients
Article Title: Thymoquinone Alterations of the Apoptotic Gene Expressions and Cell Cycle Arrest in Genetically Distinct Triple-Negative Breast Cancer Cells
doi: 10.3390/nu14102120
Figure Lengend Snippet: TQ affects cell cycle distribution in MDA-MB-231 and MDA-MB-468 TNBC cell lines. Both TNBC cell lines were treated for 24 h with TQ at three concentrations ranging from 0 to 20 µM. Sony SH800 cell sorter examination of cell dispersion using PI fluorescence. The histograms of representative Sony SH800 cell sorter experiments are shown ( A – D ) in MDA-MB-231 cells and ( F – I ) in MDA-MB-468 cells). Following three replicate studies, the bar graph shows ( E , J ) the average proportion of cells in each cell cycle phase. In MDA-MB-231 cells, TQ-treated TNBC cells showed an increase in the proportion of S phase cells and a decrease in the proportion of G2/M phase cells, while the proportion of S phase and G2/M increased in MDA-MB-468 cells. The p -value for the difference between the control and treated cells at different cell cycle phases was determined using one-way ANOVA followed by Bonferroni’s multiple comparisons test. At * p < 0.05, ** p < 0.01, the difference was declared significant and nonsignificant (ns).
Article Snippet: Data were collected using the
Techniques: Fluorescence
Journal: Nutrients
Article Title: Thymoquinone Alterations of the Apoptotic Gene Expressions and Cell Cycle Arrest in Genetically Distinct Triple-Negative Breast Cancer Cells
doi: 10.3390/nu14102120
Figure Lengend Snippet: TQ induces apoptosis in TNBC cells. The apoptotic effect of TQ in TNBC cell lines is shown in ( A – H ) (MDA-MB-231) and ( I – P ) (MDA-MB-468). TQ was applied to both cell lines for 24 h at concentrations ranging from 0 to 30 µM. An experimental medium with DMSO was used to treat the control cells. A Sony SH800 cell sorter was used to evaluate the percentage of apoptotic cells in TQ-treated samples as well as the control, and an Annexin V-FITC apoptosis kit was utilized to mark treated/control cells. The mean ± S.E.M. of three independent investigations with n = 3 each is shown by each data point in the bar graphs. After TQ treatment, the percentage of apoptotic and necrotic cells increased, while the percentage of viable cells decreased. Using one-way ANOVA and Bonferroni’s multiple comparisons test, the significance of the difference between control and each treatment was assessed. The statistically significant differences were shown by, * p < 0.05, *** p < 0.001, and **** p < 0.0001, ns, nonsignificant.
Article Snippet: Data were collected using the
Techniques: