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Image Search Results
Journal: Cardiovascular Diabetology
Article Title: Endothelial biomarkers and platelet reactivity on ticagrelor versus clopidogrel in patients after acute coronary syndrome with and without concomitant type 2 diabetes: a preliminary observational study
doi: 10.1186/s12933-022-01685-4
Figure Lengend Snippet: Platelet reactivity, sP-selectin and endothelial biomarkers in patients on DAPT with ticagrelor and clopidogrel stratified by diabetes status
Article Snippet: Additionally, asymmetric dimethylarginine (ADMA) and
Techniques:
Journal: PLoS ONE
Article Title: Dysregulated Hepatic Methionine Metabolism Drives Homocysteine Elevation in Diet-Induced Nonalcoholic Fatty Liver Disease
doi: 10.1371/journal.pone.0136822
Figure Lengend Snippet: (A) Heat map representation of substrates and methylated products of major SAM-derived transmethylation reactions (PEMT, GNMT, GAMT and PRMT) with HFHC diet for 52 weeks. (B) Levels of glycine, a substrate for GNMT, were decreased (p< 0.01) while the product sarcosine did not change between chow and HFHC group. (C) The gene expression of Gnmt , the most abundant methyltranserase in the liver, decreased significantly but only approached significance at the protein level (p = 0.06). (D) Levels of PE, the substrate for PEMT, was significantly reduced (p< 0.01) while PC trended down, resulting in a significant PC/PE ratio (p< 0.01), which suggests increase in PEMT activity There were no significant changes in the concentrations of guanidinoacetate and creatine, the substrate and product for GAMT, respectively. (E) The methylated products of PRMT activity, MMA and ADMA, were decreased significantly (p< 0.01 and p< 0.05) while the decrease in SDMA approached significance (p = 0.07). (F) The gene expression of Prmt1 , mainly responsible for the methylation of MMA and ADMA, decreased (p< 0.01) but the protein levels of PRMT1 increased significantly (p< 0.05). (G) Circulating ADMA was increased toward significance (p = 0.06), suggesting increased export to the circulation. Data are represented as mean ± SEM. Legend: arginine (Arg); asymmetric dimethylarginine (ADMA); creatine (Crea); glycine (Gly); glycine N-methyltransferase (GNMT); guanidinoacetate (GAA); guanidinoacetate methyltransferase (GAMT); homocysteine (Hcy); monomethylarginine (MMA); phosphatidylcholine (PC); phosphatidylethanolamine (PE); phosphatidylethanolamine methyltransferase (PEMT); protein arginine methyltransferase (PRMT); s-adenosylhomocysteine (SAH); s-adenosylmethionine (SAM); sarcosine (Sar); symmetric dimethylarginine (SDMA).
Article Snippet: Asymmetric-dimethylarginine (ADMA) and
Techniques: Methylation, Derivative Assay, Expressing, Activity Assay
Journal: Journal of Veterinary Internal Medicine
Article Title: RESEARCH COMMUNICATIONS OF THE 28th ECVIM‐CA CONGRESS
doi: 10.1111/jvim.15372
Figure Lengend Snippet:
Article Snippet:
Techniques: Biomarker Discovery, Clinical Proteomics, Activity Assay, Concentration Assay, Comparison, Computed Tomography, Micro-CT, Enzyme-linked Immunosorbent Assay, Expressing, Adjuvant, Electrotransfer, Histopathology, Virus, Filtration, In Vitro, Membrane, Transplantation Assay, Control, Functional Assay
Journal: PLoS ONE
Article Title: Comparative performance of IDEXX SDMA Test and the DLD SDMA ELISA for the measurement of SDMA in canine and feline serum
doi: 10.1371/journal.pone.0205030
Figure Lengend Snippet: (A) The IDEXX SDMA Test. (B) The DLD SDMA ELISA method. Solid line represents best fit linear model; shading represents 95% confidence interval around the line. Dashed line is the line of equality. Outliers are represented by *.
Article Snippet: Accuracy ,
Techniques: Enzyme-linked Immunosorbent Assay
Journal: PLoS ONE
Article Title: Comparative performance of IDEXX SDMA Test and the DLD SDMA ELISA for the measurement of SDMA in canine and feline serum
doi: 10.1371/journal.pone.0205030
Figure Lengend Snippet: Slopes and intercepts with 95% confidence intervals for the best fit linear models determined for all samples and for canine and feline samples individually.
Article Snippet: Accuracy ,
Techniques: Enzyme-linked Immunosorbent Assay
Journal: PLoS ONE
Article Title: Comparative performance of IDEXX SDMA Test and the DLD SDMA ELISA for the measurement of SDMA in canine and feline serum
doi: 10.1371/journal.pone.0205030
Figure Lengend Snippet: (A) The IDEXX SDMA Test. (B) The DLD SDMA ELISA method. Solid line represents best fit linear model; shading represents 95% confidence interval around the line. Dashed line is the line of equality. Outliers are represented by *.
Article Snippet: Accuracy ,
Techniques: Enzyme-linked Immunosorbent Assay
Journal: PLoS ONE
Article Title: Comparative performance of IDEXX SDMA Test and the DLD SDMA ELISA for the measurement of SDMA in canine and feline serum
doi: 10.1371/journal.pone.0205030
Figure Lengend Snippet: Systematic bias calculated from fit lines of IDEXX SDMA Test and DLD ELISA SDMA compared to LC-MS over a clinically relevant range of SDMA concentrations.
Article Snippet: Accuracy ,
Techniques: Enzyme-linked Immunosorbent Assay
Journal: PLoS ONE
Article Title: Comparative performance of IDEXX SDMA Test and the DLD SDMA ELISA for the measurement of SDMA in canine and feline serum
doi: 10.1371/journal.pone.0205030
Figure Lengend Snippet: (A) The IDEXX SDMA Test–Feline sample, 31.6 μg/dL (LC-MS). (B) The DLD SDMA ELISA method–Feline sample, 31.6 μg/dL (LC-MS). (C) The IDEXX SDMA Test–Canine sample, 11.8 μg/dL (LC-MS). (D) The DLD SDMA ELISA method–Canine sample, 11.8 μg/dL (LC-MS). Outliers are represented by *.
Article Snippet: Accuracy ,
Techniques: Liquid Chromatography with Mass Spectroscopy, Enzyme-linked Immunosorbent Assay
Journal: PLoS ONE
Article Title: Comparative performance of IDEXX SDMA Test and the DLD SDMA ELISA for the measurement of SDMA in canine and feline serum
doi: 10.1371/journal.pone.0205030
Figure Lengend Snippet: Variation by assay for each pooled serum sample.
Article Snippet: Accuracy ,
Techniques: Standard Deviation, Enzyme-linked Immunosorbent Assay