sdhc Search Results


93
Santa Cruz Biotechnology sc 515102
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Novus Biologicals anti sdhc igg
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Novus Biologicals 4 gpx4
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Novus Biologicals novus biologicals bio techne
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Boster Bio sdhc
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Proteintech antibody against sdhc
A) Schematic showing the xenograft tumor model with subcutaneous implantation. B) Tumor weight from B) C) Lipid ROS are measured by C11-BODIPY581/591 in EPCAM positive cells from the tumors from B). D) Schematic showing breeding strategy to generate tamoxifen inducible intestine specific <t>SDHC</t> deficient mice. E) Western blot images showing cellular and mitochondrial protein expression of SDHC 5days post tamoxifen induction via 100mg/kg body weight I.P. injection in WT ( Sdhc +/+), Het ( Sdhc +/-) and KO ( Sdhc -/-) mice. F) Representative H&E images of Sdhc F/F and Sdhc ΔIE mice fed with 350 ppm or 1000ppm iron containing chow for 7 days. G) Inflammatory histology scored for small intestine and colon of Sdhc F/F and Sdhc ΔIE mice fed with 350 ppm or 1000ppm iron containing chow for 7 days. H) Representative immunohistochemistry images showing accumulation of 4 <t>hydroxynonenal</t> <t>(4HNE)</t> in small intestine and colon of Sdhc F/F and Sdhc ΔIE mice fed with 350 ppm or 1000ppm iron containing chow for 7 days. I) Schematic showing treatment protocol for colitis associated cancer model using AOM/DSS in Sdhc F/F (WT) and Sdhc Het IE (Het) mice. J) Tumor number measured in mice from I). K) Tumor burden measured in mice from I) L) Lipid ROS measured by C11-BODIPY581/591 in EPCAM positive epithelial cells derived from I). M) Schematic showing role of heme-SDHC-CoQ axis in mitigating iron induced cell death in CRC cells. All data are mean ± SEM. One-way ANOVA with Tukey’s multiple comparisons test for (B) and (G) and t test for (C), (J), (K) and (L). ∗p < 0.05, ∗∗p < 0.01, ∗∗∗p < 0.001.
Antibody Against Sdhc, supplied by Proteintech, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Thermo Fisher gene exp sdhc hs01698067 s1
A) Schematic showing the xenograft tumor model with subcutaneous implantation. B) Tumor weight from B) C) Lipid ROS are measured by C11-BODIPY581/591 in EPCAM positive cells from the tumors from B). D) Schematic showing breeding strategy to generate tamoxifen inducible intestine specific <t>SDHC</t> deficient mice. E) Western blot images showing cellular and mitochondrial protein expression of SDHC 5days post tamoxifen induction via 100mg/kg body weight I.P. injection in WT ( Sdhc +/+), Het ( Sdhc +/-) and KO ( Sdhc -/-) mice. F) Representative H&E images of Sdhc F/F and Sdhc ΔIE mice fed with 350 ppm or 1000ppm iron containing chow for 7 days. G) Inflammatory histology scored for small intestine and colon of Sdhc F/F and Sdhc ΔIE mice fed with 350 ppm or 1000ppm iron containing chow for 7 days. H) Representative immunohistochemistry images showing accumulation of 4 <t>hydroxynonenal</t> <t>(4HNE)</t> in small intestine and colon of Sdhc F/F and Sdhc ΔIE mice fed with 350 ppm or 1000ppm iron containing chow for 7 days. I) Schematic showing treatment protocol for colitis associated cancer model using AOM/DSS in Sdhc F/F (WT) and Sdhc Het IE (Het) mice. J) Tumor number measured in mice from I). K) Tumor burden measured in mice from I) L) Lipid ROS measured by C11-BODIPY581/591 in EPCAM positive epithelial cells derived from I). M) Schematic showing role of heme-SDHC-CoQ axis in mitigating iron induced cell death in CRC cells. All data are mean ± SEM. One-way ANOVA with Tukey’s multiple comparisons test for (B) and (G) and t test for (C), (J), (K) and (L). ∗p < 0.05, ∗∗p < 0.01, ∗∗∗p < 0.001.
Gene Exp Sdhc Hs01698067 S1, supplied by Thermo Fisher, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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91
Thermo Fisher gene exp sdhc mm00481172 m1
A) Schematic showing the xenograft tumor model with subcutaneous implantation. B) Tumor weight from B) C) Lipid ROS are measured by C11-BODIPY581/591 in EPCAM positive cells from the tumors from B). D) Schematic showing breeding strategy to generate tamoxifen inducible intestine specific <t>SDHC</t> deficient mice. E) Western blot images showing cellular and mitochondrial protein expression of SDHC 5days post tamoxifen induction via 100mg/kg body weight I.P. injection in WT ( Sdhc +/+), Het ( Sdhc +/-) and KO ( Sdhc -/-) mice. F) Representative H&E images of Sdhc F/F and Sdhc ΔIE mice fed with 350 ppm or 1000ppm iron containing chow for 7 days. G) Inflammatory histology scored for small intestine and colon of Sdhc F/F and Sdhc ΔIE mice fed with 350 ppm or 1000ppm iron containing chow for 7 days. H) Representative immunohistochemistry images showing accumulation of 4 <t>hydroxynonenal</t> <t>(4HNE)</t> in small intestine and colon of Sdhc F/F and Sdhc ΔIE mice fed with 350 ppm or 1000ppm iron containing chow for 7 days. I) Schematic showing treatment protocol for colitis associated cancer model using AOM/DSS in Sdhc F/F (WT) and Sdhc Het IE (Het) mice. J) Tumor number measured in mice from I). K) Tumor burden measured in mice from I) L) Lipid ROS measured by C11-BODIPY581/591 in EPCAM positive epithelial cells derived from I). M) Schematic showing role of heme-SDHC-CoQ axis in mitigating iron induced cell death in CRC cells. All data are mean ± SEM. One-way ANOVA with Tukey’s multiple comparisons test for (B) and (G) and t test for (C), (J), (K) and (L). ∗p < 0.05, ∗∗p < 0.01, ∗∗∗p < 0.001.
Gene Exp Sdhc Mm00481172 M1, supplied by Thermo Fisher, used in various techniques. Bioz Stars score: 91/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Thermo Fisher gene exp sdhc hs00818427 m1
A) Schematic showing the xenograft tumor model with subcutaneous implantation. B) Tumor weight from B) C) Lipid ROS are measured by C11-BODIPY581/591 in EPCAM positive cells from the tumors from B). D) Schematic showing breeding strategy to generate tamoxifen inducible intestine specific <t>SDHC</t> deficient mice. E) Western blot images showing cellular and mitochondrial protein expression of SDHC 5days post tamoxifen induction via 100mg/kg body weight I.P. injection in WT ( Sdhc +/+), Het ( Sdhc +/-) and KO ( Sdhc -/-) mice. F) Representative H&E images of Sdhc F/F and Sdhc ΔIE mice fed with 350 ppm or 1000ppm iron containing chow for 7 days. G) Inflammatory histology scored for small intestine and colon of Sdhc F/F and Sdhc ΔIE mice fed with 350 ppm or 1000ppm iron containing chow for 7 days. H) Representative immunohistochemistry images showing accumulation of 4 <t>hydroxynonenal</t> <t>(4HNE)</t> in small intestine and colon of Sdhc F/F and Sdhc ΔIE mice fed with 350 ppm or 1000ppm iron containing chow for 7 days. I) Schematic showing treatment protocol for colitis associated cancer model using AOM/DSS in Sdhc F/F (WT) and Sdhc Het IE (Het) mice. J) Tumor number measured in mice from I). K) Tumor burden measured in mice from I) L) Lipid ROS measured by C11-BODIPY581/591 in EPCAM positive epithelial cells derived from I). M) Schematic showing role of heme-SDHC-CoQ axis in mitigating iron induced cell death in CRC cells. All data are mean ± SEM. One-way ANOVA with Tukey’s multiple comparisons test for (B) and (G) and t test for (C), (J), (K) and (L). ∗p < 0.05, ∗∗p < 0.01, ∗∗∗p < 0.001.
Gene Exp Sdhc Hs00818427 M1, supplied by Thermo Fisher, used in various techniques. Bioz Stars score: 85/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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90
Cusabio elisa kits
A) Schematic showing the xenograft tumor model with subcutaneous implantation. B) Tumor weight from B) C) Lipid ROS are measured by C11-BODIPY581/591 in EPCAM positive cells from the tumors from B). D) Schematic showing breeding strategy to generate tamoxifen inducible intestine specific <t>SDHC</t> deficient mice. E) Western blot images showing cellular and mitochondrial protein expression of SDHC 5days post tamoxifen induction via 100mg/kg body weight I.P. injection in WT ( Sdhc +/+), Het ( Sdhc +/-) and KO ( Sdhc -/-) mice. F) Representative H&E images of Sdhc F/F and Sdhc ΔIE mice fed with 350 ppm or 1000ppm iron containing chow for 7 days. G) Inflammatory histology scored for small intestine and colon of Sdhc F/F and Sdhc ΔIE mice fed with 350 ppm or 1000ppm iron containing chow for 7 days. H) Representative immunohistochemistry images showing accumulation of 4 <t>hydroxynonenal</t> <t>(4HNE)</t> in small intestine and colon of Sdhc F/F and Sdhc ΔIE mice fed with 350 ppm or 1000ppm iron containing chow for 7 days. I) Schematic showing treatment protocol for colitis associated cancer model using AOM/DSS in Sdhc F/F (WT) and Sdhc Het IE (Het) mice. J) Tumor number measured in mice from I). K) Tumor burden measured in mice from I) L) Lipid ROS measured by C11-BODIPY581/591 in EPCAM positive epithelial cells derived from I). M) Schematic showing role of heme-SDHC-CoQ axis in mitigating iron induced cell death in CRC cells. All data are mean ± SEM. One-way ANOVA with Tukey’s multiple comparisons test for (B) and (G) and t test for (C), (J), (K) and (L). ∗p < 0.05, ∗∗p < 0.01, ∗∗∗p < 0.001.
Elisa Kits, supplied by Cusabio, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Image Search Results


A) Schematic showing the xenograft tumor model with subcutaneous implantation. B) Tumor weight from B) C) Lipid ROS are measured by C11-BODIPY581/591 in EPCAM positive cells from the tumors from B). D) Schematic showing breeding strategy to generate tamoxifen inducible intestine specific SDHC deficient mice. E) Western blot images showing cellular and mitochondrial protein expression of SDHC 5days post tamoxifen induction via 100mg/kg body weight I.P. injection in WT ( Sdhc +/+), Het ( Sdhc +/-) and KO ( Sdhc -/-) mice. F) Representative H&E images of Sdhc F/F and Sdhc ΔIE mice fed with 350 ppm or 1000ppm iron containing chow for 7 days. G) Inflammatory histology scored for small intestine and colon of Sdhc F/F and Sdhc ΔIE mice fed with 350 ppm or 1000ppm iron containing chow for 7 days. H) Representative immunohistochemistry images showing accumulation of 4 hydroxynonenal (4HNE) in small intestine and colon of Sdhc F/F and Sdhc ΔIE mice fed with 350 ppm or 1000ppm iron containing chow for 7 days. I) Schematic showing treatment protocol for colitis associated cancer model using AOM/DSS in Sdhc F/F (WT) and Sdhc Het IE (Het) mice. J) Tumor number measured in mice from I). K) Tumor burden measured in mice from I) L) Lipid ROS measured by C11-BODIPY581/591 in EPCAM positive epithelial cells derived from I). M) Schematic showing role of heme-SDHC-CoQ axis in mitigating iron induced cell death in CRC cells. All data are mean ± SEM. One-way ANOVA with Tukey’s multiple comparisons test for (B) and (G) and t test for (C), (J), (K) and (L). ∗p < 0.05, ∗∗p < 0.01, ∗∗∗p < 0.001.

Journal: bioRxiv

Article Title: Iron addicted colorectal cancers exploit Heme-Complex II axis to resist oxidative cell death

doi: 10.1101/2025.11.05.686813

Figure Lengend Snippet: A) Schematic showing the xenograft tumor model with subcutaneous implantation. B) Tumor weight from B) C) Lipid ROS are measured by C11-BODIPY581/591 in EPCAM positive cells from the tumors from B). D) Schematic showing breeding strategy to generate tamoxifen inducible intestine specific SDHC deficient mice. E) Western blot images showing cellular and mitochondrial protein expression of SDHC 5days post tamoxifen induction via 100mg/kg body weight I.P. injection in WT ( Sdhc +/+), Het ( Sdhc +/-) and KO ( Sdhc -/-) mice. F) Representative H&E images of Sdhc F/F and Sdhc ΔIE mice fed with 350 ppm or 1000ppm iron containing chow for 7 days. G) Inflammatory histology scored for small intestine and colon of Sdhc F/F and Sdhc ΔIE mice fed with 350 ppm or 1000ppm iron containing chow for 7 days. H) Representative immunohistochemistry images showing accumulation of 4 hydroxynonenal (4HNE) in small intestine and colon of Sdhc F/F and Sdhc ΔIE mice fed with 350 ppm or 1000ppm iron containing chow for 7 days. I) Schematic showing treatment protocol for colitis associated cancer model using AOM/DSS in Sdhc F/F (WT) and Sdhc Het IE (Het) mice. J) Tumor number measured in mice from I). K) Tumor burden measured in mice from I) L) Lipid ROS measured by C11-BODIPY581/591 in EPCAM positive epithelial cells derived from I). M) Schematic showing role of heme-SDHC-CoQ axis in mitigating iron induced cell death in CRC cells. All data are mean ± SEM. One-way ANOVA with Tukey’s multiple comparisons test for (B) and (G) and t test for (C), (J), (K) and (L). ∗p < 0.05, ∗∗p < 0.01, ∗∗∗p < 0.001.

Article Snippet: Followed by blocking with 5% goat serum in PBS and sections were then probed with primary antibody against SDHC (Proteintech, 14575-AP) or 4HNE (R&D Systems, MAB3249-SP) diluted at 1:500 in the blocking solution.

Techniques: Western Blot, Expressing, Injection, Immunohistochemistry, Derivative Assay