Journal: PLoS ONE

Article Title: Antibody engineering to generate SKY59, a long-acting anti-C5 recycling antibody

doi: 10.1371/journal.pone.0209509

Figure Lengend Snippet: Potential immunogenicity of SKY59 (light blue), the lead antibody CFA0305 (orange), and other approved antibodies was evaluated in silico . Antibodies with a lower Tregitope-adjusted EpiMatrix score (A) or a lower Epibase immunogenicity risk score (B) are considered to be less immunogenic.

Article Snippet: The potential immunogenicity of each antibody was evaluated in silico using Tregitope-adjusted EpiMatrix score (EpiVax) [ – ] and Epibase immunogenicity risk score (Lonza) [ ].

Techniques: In Silico

Journal:

Article Title: Validation of the INNO-LIA Syphilis Kit as a Confirmatory Assay for Treponema pallidum Antibodies

doi:

Figure Lengend Snippet: Layout of INNO-LIA Syphilis kit strip.

Article Snippet: A. Ebel thanks Innogenetics for providing the INNO-LIA Syphilis kits free of charge.

Techniques: Stripping Membranes

Journal:

Article Title: Validation of the INNO-LIA Syphilis Kit as a Confirmatory Assay for Treponema pallidum Antibodies

doi:

Figure Lengend Snippet: Representative patterns of reactivity with INNO-LIA Syphilis kit. Control lines are indicated (3+, 1+, and ±); antigen lines are those for the TpN47, TpN17, TpN15, and TmpA antigens, respectively. Sera correspond to the following (from top to bottom): six positive samples with indeterminate (samples 547, 800, and 820) or weakly positive (samples 601, 612, and 668) consensus results, two samples with indeterminate results with one negative (sample 207) and one positive (sample 518) consensus result; and three negative samples (samples 768, 769, and 770) with positive serology for Lyme borreliosis.

Article Snippet: A. Ebel thanks Innogenetics for providing the INNO-LIA Syphilis kits free of charge.

Techniques:

Journal:

Article Title: Validation of the INNO-LIA Syphilis Kit as a Confirmatory Assay for Treponema pallidum Antibodies

doi:

Figure Lengend Snippet: Comparison of INNO-LIA Syphilis kit results and classical testing consensus results

Article Snippet: A. Ebel thanks Innogenetics for providing the INNO-LIA Syphilis kits free of charge.

Techniques: Comparison

Journal:

Article Title: Validation of the INNO-LIA Syphilis Kit as a Confirmatory Assay for Treponema pallidum Antibodies

doi:

Figure Lengend Snippet: INNO-LIA Syphilis kit results for sera with clinical condition documentation

Article Snippet: A. Ebel thanks Innogenetics for providing the INNO-LIA Syphilis kits free of charge.

Techniques: Injection

Journal:

Article Title: Validation of the INNO-LIA Syphilis Kit as a Confirmatory Assay for Treponema pallidum Antibodies

doi:

Figure Lengend Snippet: INNO-LIA Syphilis kit results for sera containing antibodies for other infectious or autoimmune diseases

Article Snippet: A. Ebel thanks Innogenetics for providing the INNO-LIA Syphilis kits free of charge.

Techniques: Virus