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Image Search Results
Journal: Toxicon : official journal of the International Society on Toxinology
Article Title: Functional characterization of six aspartate (D) recombinant mojastin mutants (r-Moj): a second aspartate amino acid carboxyl to the RGD in r-Moj-D_ peptides is not sufficient to induce apoptosis of SK-Mel-28 cells
doi: 10.1016/j.toxicon.2016.04.038
Figure Lengend Snippet: αvβ3 integrin cell surface expression on untransduced, scrambled shRNA, and αv stable knocked down SK-Mel-28 cells. p<0.001 (***). αvβ5 integrin expression was not examined since we demonstrated that SK-Mel-28 cells do not express the β5 subunit (Seoane et al. 2010).
Article Snippet: Integrin αv gene expression knockdown Inhibition of integrin αv expression was performed in SK-Mel-28 cells using
Techniques: Expressing, shRNA
Journal: Toxicon : official journal of the International Society on Toxinology
Article Title: Functional characterization of six aspartate (D) recombinant mojastin mutants (r-Moj): a second aspartate amino acid carboxyl to the RGD in r-Moj-D_ peptides is not sufficient to induce apoptosis of SK-Mel-28 cells
doi: 10.1016/j.toxicon.2016.04.038
Figure Lengend Snippet: r-Moj-DL, r-Moj-DM, and r-Moj-DN peptides induced apoptosis of SK-Mel-28 cells by binding to the αv integrin. p=0.05 (*), p=0.01 (**), p<0.001 (***).
Article Snippet: Integrin αv gene expression knockdown Inhibition of integrin αv expression was performed in SK-Mel-28 cells using
Techniques: Binding Assay
Journal: Toxicon : official journal of the International Society on Toxinology
Article Title: Functional characterization of six aspartate (D) recombinant mojastin mutants (r-Moj): a second aspartate amino acid carboxyl to the RGD in r-Moj-D_ peptides is not sufficient to induce apoptosis of SK-Mel-28 cells
doi: 10.1016/j.toxicon.2016.04.038
Figure Lengend Snippet: All r-Moj-D_ mutant peptides inhibited proliferation of SK-Mel-28 cells by binding to the αv integrin. The scrambled shRNA control treated cells are not shown, since these cells grew at much slower rate than untransduced or αv knocked down cells.
Article Snippet: Integrin αv gene expression knockdown Inhibition of integrin αv expression was performed in SK-Mel-28 cells using
Techniques: Mutagenesis, Binding Assay, shRNA, Control