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SBP-7455（Cat No.:I036065） is a dual inhibitor of ULK1 and ULK2 (ULK1/2), exhibiting enhanced binding affinity compared to SBI-0206965. It effectively inhibits the enzymatic activity of ULK1/2 both in vitro and in cells. SBP-7455 demonstrates potent
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Selleck Chemicals
sbp 7455 Sbp 7455, supplied by Selleck Chemicals, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more https://www.bioz.com/product/sbp-7455/pmc12752765-62-0-2?v=Selleck+Chemicals Average 93 stars, based on 1 article reviews
sbp 7455 - by Bioz Stars,
2026-08
93/100 stars
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InformationSBP-7455 (compound 26) is a dual inhibitor of ULK1 and ULK2 that potently inhibits ULK1/2 enzymatic activity in vitro and in vivo. SBP-7455 inhibits starvation-induced autophagic flux in TNBC cells.
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SBP-7455 is a potent, high affinity and orally active dual ULK1/ULK2 autophagy inhibitor with IC50s of 13 nM and 476 nM in the ADP-Glo assays, respectively. SBP-7455 potently inhibits ULK1/2 enzymatic activity and can be
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