ryanodine Search Results


anti ryanodine receptor 3  (Alomone Labs)
92
Alomone Labs anti ryanodine receptor 3
Anti Ryanodine Receptor 3, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 92/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/ryanodine/pmc07766921-32-0-13?v=Alomone+Labs
Average 92 stars, based on 1 article reviews
anti ryanodine receptor 3 - by Bioz Stars, 2026-08
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ryanodine  (Tocris)
95
Tocris ryanodine
Ryanodine, supplied by Tocris, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/ryanodine/pm31707211-48-8-19?v=Tocris
Average 95 stars, based on 1 article reviews
ryanodine - by Bioz Stars, 2026-08
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3h ryanodine  (Revvity)
91
Revvity 3h ryanodine
3h Ryanodine, supplied by Revvity, used in various techniques. Bioz Stars score: 91/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/ryanodine/10__1074_slash_jbc__m705702200-79-29-30?v=Revvity
Average 91 stars, based on 1 article reviews
3h ryanodine - by Bioz Stars, 2026-08
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ryr2  (Novus Biologicals)
94
Novus Biologicals ryr2
Ryr2, supplied by Novus Biologicals, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/ryanodine/pmc12866931-81-99-101?v=Novus+Biologicals
Average 94 stars, based on 1 article reviews
ryr2 - by Bioz Stars, 2026-08
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ryanodine  (Alomone Labs)
93
Alomone Labs ryanodine
Figure 1. Characterization of double knock-in mice A, generation of the double knock-in (DKI) mouse line. Please see the Methods section for a complete description. B, the total <t>ryanodine</t> receptor (RyR2) expression is comparable in RyR2-DKI and wild-type (WT) animals (Student’s two-sample t test, n = 6, mixed males and females). C, western blot analysis confirms the absence of phospho-epitopes Ser2808 and Ser2814 both in control conditions and in the presence of the catalytic subunit of protein kinase A (cPKA) or Ca2+/calmodulin (10 μmol/l Ca2+). A marked increase of Ser2030 phosphorylation after cPKA can be seen in the blots from both animals. D, absence of phosphorylation at Ser2808 and Ser2814 confirmed by immunofluorescence in isolated myocytes. E, echocardiographic M-mode recording in WT and RyR2-DKI mice. Ventricular mass to body weight ratio and ejection fraction were not significantly different, but the DKI mice exhibited a higher heart rate. n = 13 (5 males and 8 females) for WT; n = 13 (6 males and 7 females) for RyR2-DKI. Significant differences (†P < 0.05 vs. WT) were assessed by Student’s two-sample t test and, in the case of heart rate, by the Wilcoxon rank sum test (to test whether a data sample comes from a normal distribution, the Anderson–Darling test was used).
Ryanodine, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/ryanodine/10__1113_slash_jp286453-177-4-7?v=Alomone+Labs
Average 93 stars, based on 1 article reviews
ryanodine - by Bioz Stars, 2026-08
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ryr2  (OriGene)
91
OriGene ryr2
Figure 1. Characterization of double knock-in mice A, generation of the double knock-in (DKI) mouse line. Please see the Methods section for a complete description. B, the total <t>ryanodine</t> receptor (RyR2) expression is comparable in RyR2-DKI and wild-type (WT) animals (Student’s two-sample t test, n = 6, mixed males and females). C, western blot analysis confirms the absence of phospho-epitopes Ser2808 and Ser2814 both in control conditions and in the presence of the catalytic subunit of protein kinase A (cPKA) or Ca2+/calmodulin (10 μmol/l Ca2+). A marked increase of Ser2030 phosphorylation after cPKA can be seen in the blots from both animals. D, absence of phosphorylation at Ser2808 and Ser2814 confirmed by immunofluorescence in isolated myocytes. E, echocardiographic M-mode recording in WT and RyR2-DKI mice. Ventricular mass to body weight ratio and ejection fraction were not significantly different, but the DKI mice exhibited a higher heart rate. n = 13 (5 males and 8 females) for WT; n = 13 (6 males and 7 females) for RyR2-DKI. Significant differences (†P < 0.05 vs. WT) were assessed by Student’s two-sample t test and, in the case of heart rate, by the Wilcoxon rank sum test (to test whether a data sample comes from a normal distribution, the Anderson–Darling test was used).
Ryr2, supplied by OriGene, used in various techniques. Bioz Stars score: 91/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/ryanodine/pm39803363-89-56-55?v=OriGene
Average 91 stars, based on 1 article reviews
ryr2 - by Bioz Stars, 2026-08
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anti ryr antibodies  (OriGene)
92
OriGene anti ryr antibodies
Figure 1. Characterization of double knock-in mice A, generation of the double knock-in (DKI) mouse line. Please see the Methods section for a complete description. B, the total <t>ryanodine</t> receptor (RyR2) expression is comparable in RyR2-DKI and wild-type (WT) animals (Student’s two-sample t test, n = 6, mixed males and females). C, western blot analysis confirms the absence of phospho-epitopes Ser2808 and Ser2814 both in control conditions and in the presence of the catalytic subunit of protein kinase A (cPKA) or Ca2+/calmodulin (10 μmol/l Ca2+). A marked increase of Ser2030 phosphorylation after cPKA can be seen in the blots from both animals. D, absence of phosphorylation at Ser2808 and Ser2814 confirmed by immunofluorescence in isolated myocytes. E, echocardiographic M-mode recording in WT and RyR2-DKI mice. Ventricular mass to body weight ratio and ejection fraction were not significantly different, but the DKI mice exhibited a higher heart rate. n = 13 (5 males and 8 females) for WT; n = 13 (6 males and 7 females) for RyR2-DKI. Significant differences (†P < 0.05 vs. WT) were assessed by Student’s two-sample t test and, in the case of heart rate, by the Wilcoxon rank sum test (to test whether a data sample comes from a normal distribution, the Anderson–Darling test was used).
Anti Ryr Antibodies, supplied by OriGene, used in various techniques. Bioz Stars score: 92/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/ryanodine/pmc11592670-113-7-18?v=OriGene
Average 92 stars, based on 1 article reviews
anti ryr antibodies - by Bioz Stars, 2026-08
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anti ryanodine receptor 1  (Alomone Labs)
93
Alomone Labs anti ryanodine receptor 1
Figure 1. Characterization of double knock-in mice A, generation of the double knock-in (DKI) mouse line. Please see the Methods section for a complete description. B, the total <t>ryanodine</t> receptor (RyR2) expression is comparable in RyR2-DKI and wild-type (WT) animals (Student’s two-sample t test, n = 6, mixed males and females). C, western blot analysis confirms the absence of phospho-epitopes Ser2808 and Ser2814 both in control conditions and in the presence of the catalytic subunit of protein kinase A (cPKA) or Ca2+/calmodulin (10 μmol/l Ca2+). A marked increase of Ser2030 phosphorylation after cPKA can be seen in the blots from both animals. D, absence of phosphorylation at Ser2808 and Ser2814 confirmed by immunofluorescence in isolated myocytes. E, echocardiographic M-mode recording in WT and RyR2-DKI mice. Ventricular mass to body weight ratio and ejection fraction were not significantly different, but the DKI mice exhibited a higher heart rate. n = 13 (5 males and 8 females) for WT; n = 13 (6 males and 7 females) for RyR2-DKI. Significant differences (†P < 0.05 vs. WT) were assessed by Student’s two-sample t test and, in the case of heart rate, by the Wilcoxon rank sum test (to test whether a data sample comes from a normal distribution, the Anderson–Darling test was used).
Anti Ryanodine Receptor 1, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/ryanodine/pmc07766921-30-0-13?v=Alomone+Labs
Average 93 stars, based on 1 article reviews
anti ryanodine receptor 1 - by Bioz Stars, 2026-08
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2 ryr2 antibody  (Alomone Labs)
93
Alomone Labs 2 ryr2 antibody
Figure 1. Characterization of double knock-in mice A, generation of the double knock-in (DKI) mouse line. Please see the Methods section for a complete description. B, the total <t>ryanodine</t> receptor (RyR2) expression is comparable in RyR2-DKI and wild-type (WT) animals (Student’s two-sample t test, n = 6, mixed males and females). C, western blot analysis confirms the absence of phospho-epitopes Ser2808 and Ser2814 both in control conditions and in the presence of the catalytic subunit of protein kinase A (cPKA) or Ca2+/calmodulin (10 μmol/l Ca2+). A marked increase of Ser2030 phosphorylation after cPKA can be seen in the blots from both animals. D, absence of phosphorylation at Ser2808 and Ser2814 confirmed by immunofluorescence in isolated myocytes. E, echocardiographic M-mode recording in WT and RyR2-DKI mice. Ventricular mass to body weight ratio and ejection fraction were not significantly different, but the DKI mice exhibited a higher heart rate. n = 13 (5 males and 8 females) for WT; n = 13 (6 males and 7 females) for RyR2-DKI. Significant differences (†P < 0.05 vs. WT) were assessed by Student’s two-sample t test and, in the case of heart rate, by the Wilcoxon rank sum test (to test whether a data sample comes from a normal distribution, the Anderson–Darling test was used).
2 Ryr2 Antibody, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/ryanodine/pm39947630-190-14-16?v=Alomone+Labs
Average 93 stars, based on 1 article reviews
2 ryr2 antibody - by Bioz Stars, 2026-08
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phospho ryanodine receptor type 2  (Santa Cruz Biotechnology)
93
Santa Cruz Biotechnology phospho ryanodine receptor type 2
Figure 1. Characterization of double knock-in mice A, generation of the double knock-in (DKI) mouse line. Please see the Methods section for a complete description. B, the total <t>ryanodine</t> receptor (RyR2) expression is comparable in RyR2-DKI and wild-type (WT) animals (Student’s two-sample t test, n = 6, mixed males and females). C, western blot analysis confirms the absence of phospho-epitopes Ser2808 and Ser2814 both in control conditions and in the presence of the catalytic subunit of protein kinase A (cPKA) or Ca2+/calmodulin (10 μmol/l Ca2+). A marked increase of Ser2030 phosphorylation after cPKA can be seen in the blots from both animals. D, absence of phosphorylation at Ser2808 and Ser2814 confirmed by immunofluorescence in isolated myocytes. E, echocardiographic M-mode recording in WT and RyR2-DKI mice. Ventricular mass to body weight ratio and ejection fraction were not significantly different, but the DKI mice exhibited a higher heart rate. n = 13 (5 males and 8 females) for WT; n = 13 (6 males and 7 females) for RyR2-DKI. Significant differences (†P < 0.05 vs. WT) were assessed by Student’s two-sample t test and, in the case of heart rate, by the Wilcoxon rank sum test (to test whether a data sample comes from a normal distribution, the Anderson–Darling test was used).
Phospho Ryanodine Receptor Type 2, supplied by Santa Cruz Biotechnology, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/ryanodine/pm41124862-76-94-123?v=Santa+Cruz+Biotechnology
Average 93 stars, based on 1 article reviews
phospho ryanodine receptor type 2 - by Bioz Stars, 2026-08
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Image Search Results


Figure 1. Characterization of double knock-in mice A, generation of the double knock-in (DKI) mouse line. Please see the Methods section for a complete description. B, the total ryanodine receptor (RyR2) expression is comparable in RyR2-DKI and wild-type (WT) animals (Student’s two-sample t test, n = 6, mixed males and females). C, western blot analysis confirms the absence of phospho-epitopes Ser2808 and Ser2814 both in control conditions and in the presence of the catalytic subunit of protein kinase A (cPKA) or Ca2+/calmodulin (10 μmol/l Ca2+). A marked increase of Ser2030 phosphorylation after cPKA can be seen in the blots from both animals. D, absence of phosphorylation at Ser2808 and Ser2814 confirmed by immunofluorescence in isolated myocytes. E, echocardiographic M-mode recording in WT and RyR2-DKI mice. Ventricular mass to body weight ratio and ejection fraction were not significantly different, but the DKI mice exhibited a higher heart rate. n = 13 (5 males and 8 females) for WT; n = 13 (6 males and 7 females) for RyR2-DKI. Significant differences (†P < 0.05 vs. WT) were assessed by Student’s two-sample t test and, in the case of heart rate, by the Wilcoxon rank sum test (to test whether a data sample comes from a normal distribution, the Anderson–Darling test was used).

Journal: The Journal of Physiology

Article Title: Dual ablation of the RyR2‐Ser2808 and RyR2‐Ser2814 sites increases propensity for pro‐arrhythmic spontaneous Ca2+ releases

doi: 10.1113/jp286453

Figure Lengend Snippet: Figure 1. Characterization of double knock-in mice A, generation of the double knock-in (DKI) mouse line. Please see the Methods section for a complete description. B, the total ryanodine receptor (RyR2) expression is comparable in RyR2-DKI and wild-type (WT) animals (Student’s two-sample t test, n = 6, mixed males and females). C, western blot analysis confirms the absence of phospho-epitopes Ser2808 and Ser2814 both in control conditions and in the presence of the catalytic subunit of protein kinase A (cPKA) or Ca2+/calmodulin (10 μmol/l Ca2+). A marked increase of Ser2030 phosphorylation after cPKA can be seen in the blots from both animals. D, absence of phosphorylation at Ser2808 and Ser2814 confirmed by immunofluorescence in isolated myocytes. E, echocardiographic M-mode recording in WT and RyR2-DKI mice. Ventricular mass to body weight ratio and ejection fraction were not significantly different, but the DKI mice exhibited a higher heart rate. n = 13 (5 males and 8 females) for WT; n = 13 (6 males and 7 females) for RyR2-DKI. Significant differences (†P < 0.05 vs. WT) were assessed by Student’s two-sample t test and, in the case of heart rate, by the Wilcoxon rank sum test (to test whether a data sample comes from a normal distribution, the Anderson–Darling test was used).

Article Snippet: A low dose of ryanodine (50 nmol/l; Alomone Labs, Jerusalem, Israel) was used to evoke repetitive Ca2+ sparks as previously described (Sobie et al., 2005).

Techniques: Knock-In, Expressing, Western Blot, Control, Phospho-proteomics, Immunofluorescence, Isolation

Figure 8. Spark recovery analysis indicates elevated Ca2+ sensitivity in RyR2-double knock-in cardio- myocytes A, representative line-scan image in the presence of a very low concentration of ryanodine (50 nmol/l), which can induce repetitive sparks. B, histograms of delays of Ca2+ sparks in control conditions and in the presence of 100 nmol/l isoprenaline (Iso). Black vertical lines are medians of respective spark-to-spark delay distributions. C, summary and comparison of medians with 95% confidence intervals (CIs) of each individual group. Wild type (WT): control, N = 6, n = 25, 497 spark pairs; Iso, N = 6, n = 35, 1334 spark pairs. RyR2-double knock-in (DKI): control, N = 6, n = 18, 563 spark pairs; Iso, N = 6, n = 19, 1120 spark pairs. Individual groups were tested for significance using the Kruskal–Wallis test with Dunn–Sidak post hoc test.

Journal: The Journal of Physiology

Article Title: Dual ablation of the RyR2‐Ser2808 and RyR2‐Ser2814 sites increases propensity for pro‐arrhythmic spontaneous Ca2+ releases

doi: 10.1113/jp286453

Figure Lengend Snippet: Figure 8. Spark recovery analysis indicates elevated Ca2+ sensitivity in RyR2-double knock-in cardio- myocytes A, representative line-scan image in the presence of a very low concentration of ryanodine (50 nmol/l), which can induce repetitive sparks. B, histograms of delays of Ca2+ sparks in control conditions and in the presence of 100 nmol/l isoprenaline (Iso). Black vertical lines are medians of respective spark-to-spark delay distributions. C, summary and comparison of medians with 95% confidence intervals (CIs) of each individual group. Wild type (WT): control, N = 6, n = 25, 497 spark pairs; Iso, N = 6, n = 35, 1334 spark pairs. RyR2-double knock-in (DKI): control, N = 6, n = 18, 563 spark pairs; Iso, N = 6, n = 19, 1120 spark pairs. Individual groups were tested for significance using the Kruskal–Wallis test with Dunn–Sidak post hoc test.

Article Snippet: A low dose of ryanodine (50 nmol/l; Alomone Labs, Jerusalem, Israel) was used to evoke repetitive Ca2+ sparks as previously described (Sobie et al., 2005).

Techniques: Knock-In, Concentration Assay, Control, Comparison