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R&D Systems
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Image Search Results
Journal: Molecules (Basel, Switzerland)
Article Title: The C30-Modulation of Betulinic Acid Using 1,2,4-Triazole: A Promising Strategy for Increasing Its Antimelanoma Cytotoxic Potential.
doi: 10.3390/molecules27227807
Figure Lengend Snippet: Figure 3. Cell viability of RPMI-7951 cells after 24 h treatment with BA-TZ 0.08, 0.4, 2, 10 and 50 µM, determined using the MTT assay. Untreated cells were used as negative control, while 5-FU was used as positive control. The results are expressed as cell viability percentage (%) normalized to the negative control (100%). The data represent the mean values ± SD of three independent experiments performed in triplicate. The statistical differences vs. the negative control was determined using two-way ANOVA analysis followed by Bonferroni’s multiple comparisons post-test (* p < 0.05 and *** p < 0.0001).
Article Snippet: The cell lines selected for this study, HaCaT—immortalized human keratinocytes, were purchased from CLS Cell Lines Service GmbH (Eppelheim, Germany), and
Techniques: MTT Assay, Negative Control, Positive Control
Journal: Molecules (Basel, Switzerland)
Article Title: The C30-Modulation of Betulinic Acid Using 1,2,4-Triazole: A Promising Strategy for Increasing Its Antimelanoma Cytotoxic Potential.
doi: 10.3390/molecules27227807
Figure Lengend Snippet: Figure 4. Morphological observation of RPMI-7951 cells using DAPI staining, after treatment with TZ and BA-TZ at 10 and 50 µM for 24 h. The staurosporine solution (5 µM) was used as positive control for apoptotic changes at the nuclear level. The yellow arrows represent signs of apoptosis, such as nuclear shrinkage, condensation, fragmentation and cellular membrane disruption.
Article Snippet: The cell lines selected for this study, HaCaT—immortalized human keratinocytes, were purchased from CLS Cell Lines Service GmbH (Eppelheim, Germany), and
Techniques: Staining, Positive Control, Membrane, Disruption
Journal: Molecules (Basel, Switzerland)
Article Title: The C30-Modulation of Betulinic Acid Using 1,2,4-Triazole: A Promising Strategy for Increasing Its Antimelanoma Cytotoxic Potential.
doi: 10.3390/molecules27227807
Figure Lengend Snippet: Figure 6. Mitochondrial respiratory rates of permeabilized RPMI-7951 cells following 24 h treatment with BA-TZ 10 µM. Data represent the mean ± SD of five individual experiments. The statistical differences vs. control was determined using one-way ANOVA analysis followed by Tukey’s multiple comparisons post-test. Values with p < 0.05 were considered to have a statistically significant difference (*p < 0.05, ** p < 0.01 and *** p < 0.001).
Article Snippet: The cell lines selected for this study, HaCaT—immortalized human keratinocytes, were purchased from CLS Cell Lines Service GmbH (Eppelheim, Germany), and
Techniques: Control