queuine Search Results


N/A
QTRT2 antibody detects Queuine tRNA-ribosyltransferase subunit 2, encoded by the QTRT2 gene on chromosome 6p25.1. QTRT2 antibody is widely used in RNA modification, translation, and metabolism research. QTRT2 partners with QTRT1 to form the heterodimeric
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93
Santa Cruz Biotechnology queuine hydrochloride
Interaction analysis of the control drug Gemcitabine and the proposed nutraceutical therapeutics <t>Queuine</t> and Thiamine with the MAP4K4 binding site. ( A ) 3D binding pose of Gemcitabine (left) and 2D representation (right) of Gemcitabine docked in the MAP4K4 binding site. ( B ) 3D and 2D binding pose of Queuine ( C ) 3D and 2D binding pose of Thiamine. Coloring schemes: hydrogen bonding (purple arrows), pi-pi stacking (green line), and pi-cation interactions (red line)
Queuine Hydrochloride, supplied by Santa Cruz Biotechnology, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/queuine/pmc12465891-121-0-2?v=Santa+Cruz+Biotechnology
Average 93 stars, based on 1 article reviews
queuine hydrochloride - by Bioz Stars, 2026-08
93/100 stars
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90
Marburg GmbH queuine
Interaction analysis of the control drug Gemcitabine and the proposed nutraceutical therapeutics <t>Queuine</t> and Thiamine with the MAP4K4 binding site. ( A ) 3D binding pose of Gemcitabine (left) and 2D representation (right) of Gemcitabine docked in the MAP4K4 binding site. ( B ) 3D and 2D binding pose of Queuine ( C ) 3D and 2D binding pose of Thiamine. Coloring schemes: hydrogen bonding (purple arrows), pi-pi stacking (green line), and pi-cation interactions (red line)
Queuine, supplied by Marburg GmbH, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/queuine/10__1128_slash_mbio__03549___20-359-5-14?v=Marburg+GmbH
Average 90 stars, based on 1 article reviews
queuine - by Bioz Stars, 2026-08
90/100 stars
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90
Holobiome Inc queuine
Interaction analysis of the control drug Gemcitabine and the proposed nutraceutical therapeutics <t>Queuine</t> and Thiamine with the MAP4K4 binding site. ( A ) 3D binding pose of Gemcitabine (left) and 2D representation (right) of Gemcitabine docked in the MAP4K4 binding site. ( B ) 3D and 2D binding pose of Queuine ( C ) 3D and 2D binding pose of Thiamine. Coloring schemes: hydrogen bonding (purple arrows), pi-pi stacking (green line), and pi-cation interactions (red line)
Queuine, supplied by Holobiome Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/queuine/pm32381701-116-12-9?v=Holobiome+Inc
Average 90 stars, based on 1 article reviews
queuine - by Bioz Stars, 2026-08
90/100 stars
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N/A
QTRT1 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 428 amino acids (1-403 a.a) and having a molecular mass of 46.7kDa. QTRT1 is fused to a 25 amino acid His-tag at
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N/A
Queuine TRNA-Ribosyltransferase Domain Containing 1, Human Recombinant; 10 ug
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N/A
QTRTD1, 1-415aa Human, His tag, E.coliQTRTD1 interacts with QTRT1 to form an active queuine tRNA-ribosyltransferase. This enzyme exchanges queuine for the guanine at the wobble position of tRNAs with GUN anticodons (tRNA-Asp, -Asn, -His and
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N/A
Queuine TRNA-Ribosyltransferase 1, Human Recombinant; 5 ug
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Image Search Results


Interaction analysis of the control drug Gemcitabine and the proposed nutraceutical therapeutics Queuine and Thiamine with the MAP4K4 binding site. ( A ) 3D binding pose of Gemcitabine (left) and 2D representation (right) of Gemcitabine docked in the MAP4K4 binding site. ( B ) 3D and 2D binding pose of Queuine ( C ) 3D and 2D binding pose of Thiamine. Coloring schemes: hydrogen bonding (purple arrows), pi-pi stacking (green line), and pi-cation interactions (red line)

Journal: BMC Biotechnology

Article Title: In silico screening and in vitro biological evaluation reveal Queuine as a promising MAP4K4 inhibitor for treating pancreatic cancer

doi: 10.1186/s12896-025-01033-w

Figure Lengend Snippet: Interaction analysis of the control drug Gemcitabine and the proposed nutraceutical therapeutics Queuine and Thiamine with the MAP4K4 binding site. ( A ) 3D binding pose of Gemcitabine (left) and 2D representation (right) of Gemcitabine docked in the MAP4K4 binding site. ( B ) 3D and 2D binding pose of Queuine ( C ) 3D and 2D binding pose of Thiamine. Coloring schemes: hydrogen bonding (purple arrows), pi-pi stacking (green line), and pi-cation interactions (red line)

Article Snippet: Queuine hydrochloride (Santa Cruz) was dissolved in dimethyl sulfoxide (DMSO).

Techniques: Control, Binding Assay

Protein-ligand complex root mean square deviation (RMSD) ( A ) and root mean square fluctuation (RMSF) ( B ) plots for the apo, Gemcitabine, Queuine, and Thiamine bound forms of the MAP4K4 protein

Journal: BMC Biotechnology

Article Title: In silico screening and in vitro biological evaluation reveal Queuine as a promising MAP4K4 inhibitor for treating pancreatic cancer

doi: 10.1186/s12896-025-01033-w

Figure Lengend Snippet: Protein-ligand complex root mean square deviation (RMSD) ( A ) and root mean square fluctuation (RMSF) ( B ) plots for the apo, Gemcitabine, Queuine, and Thiamine bound forms of the MAP4K4 protein

Article Snippet: Queuine hydrochloride (Santa Cruz) was dissolved in dimethyl sulfoxide (DMSO).

Techniques:

Schematic showing the durability of ligand-protein interactions during MD simulations. ( A ) Queuine-protein contacts prolonged for more than 50% of the simulation time. ( B ) Thiamine has shorter-lived less prolonged contacts

Journal: BMC Biotechnology

Article Title: In silico screening and in vitro biological evaluation reveal Queuine as a promising MAP4K4 inhibitor for treating pancreatic cancer

doi: 10.1186/s12896-025-01033-w

Figure Lengend Snippet: Schematic showing the durability of ligand-protein interactions during MD simulations. ( A ) Queuine-protein contacts prolonged for more than 50% of the simulation time. ( B ) Thiamine has shorter-lived less prolonged contacts

Article Snippet: Queuine hydrochloride (Santa Cruz) was dissolved in dimethyl sulfoxide (DMSO).

Techniques:

Final snapshots at the end of the 100 ns MD simulations for Queuine ( A ), Thiamine ( B ), and Gemcitabine ( C )

Journal: BMC Biotechnology

Article Title: In silico screening and in vitro biological evaluation reveal Queuine as a promising MAP4K4 inhibitor for treating pancreatic cancer

doi: 10.1186/s12896-025-01033-w

Figure Lengend Snippet: Final snapshots at the end of the 100 ns MD simulations for Queuine ( A ), Thiamine ( B ), and Gemcitabine ( C )

Article Snippet: Queuine hydrochloride (Santa Cruz) was dissolved in dimethyl sulfoxide (DMSO).

Techniques:

Viability of Panc-1 cells compared with that of the control group after exposure to different concentrations of Queuine ( A ), Thiamine ( B ) and Gemcitabine ( C ) for 48 h. The results represent the average ± SEM of the results from each experiment, which were repeated three times at different times with the same concentration ranges. The statistical significance was evaluated according to a p-value of < 0.05.Compared with the control, *p< \0.05, **p< \0.01

Journal: BMC Biotechnology

Article Title: In silico screening and in vitro biological evaluation reveal Queuine as a promising MAP4K4 inhibitor for treating pancreatic cancer

doi: 10.1186/s12896-025-01033-w

Figure Lengend Snippet: Viability of Panc-1 cells compared with that of the control group after exposure to different concentrations of Queuine ( A ), Thiamine ( B ) and Gemcitabine ( C ) for 48 h. The results represent the average ± SEM of the results from each experiment, which were repeated three times at different times with the same concentration ranges. The statistical significance was evaluated according to a p-value of < 0.05.Compared with the control, *p< \0.05, **p< \0.01

Article Snippet: Queuine hydrochloride (Santa Cruz) was dissolved in dimethyl sulfoxide (DMSO).

Techniques: Control, Concentration Assay

Effects of different concentrations of Queuine and Gemcitabine on MAP4K4 activity. Absorbance values on the y-axis represent the enzyme amount measured using an ELISA kit, with different concentrations of Queuine ( A ) and Gemsitabine ( B ) indicated on the x-axis. The differences between the bar pairs marked with * ( p < 0.05) and *** ( p < 0.001) are significant

Journal: BMC Biotechnology

Article Title: In silico screening and in vitro biological evaluation reveal Queuine as a promising MAP4K4 inhibitor for treating pancreatic cancer

doi: 10.1186/s12896-025-01033-w

Figure Lengend Snippet: Effects of different concentrations of Queuine and Gemcitabine on MAP4K4 activity. Absorbance values on the y-axis represent the enzyme amount measured using an ELISA kit, with different concentrations of Queuine ( A ) and Gemsitabine ( B ) indicated on the x-axis. The differences between the bar pairs marked with * ( p < 0.05) and *** ( p < 0.001) are significant

Article Snippet: Queuine hydrochloride (Santa Cruz) was dissolved in dimethyl sulfoxide (DMSO).

Techniques: Activity Assay, Enzyme-linked Immunosorbent Assay

Viability of Panc-1 cells compared with that of the control group after exposure to combined treatment of Queuine (QUE) and Gemcitabine (GEM) for 48 h. A ) Queuine (0.25 µM) with gemcitabine combination, B ) Queuine (1.25 µM) with gemcitabine combination

Journal: BMC Biotechnology

Article Title: In silico screening and in vitro biological evaluation reveal Queuine as a promising MAP4K4 inhibitor for treating pancreatic cancer

doi: 10.1186/s12896-025-01033-w

Figure Lengend Snippet: Viability of Panc-1 cells compared with that of the control group after exposure to combined treatment of Queuine (QUE) and Gemcitabine (GEM) for 48 h. A ) Queuine (0.25 µM) with gemcitabine combination, B ) Queuine (1.25 µM) with gemcitabine combination

Article Snippet: Queuine hydrochloride (Santa Cruz) was dissolved in dimethyl sulfoxide (DMSO).

Techniques: Control

Synergetic effects of Queuine and Gemcitabine on MAP4K4 activity. Absorbance values represent the enzyme amount measured using an ELISA kit. The difference between bar pairs marked with *** are significant at p < 0.001

Journal: BMC Biotechnology

Article Title: In silico screening and in vitro biological evaluation reveal Queuine as a promising MAP4K4 inhibitor for treating pancreatic cancer

doi: 10.1186/s12896-025-01033-w

Figure Lengend Snippet: Synergetic effects of Queuine and Gemcitabine on MAP4K4 activity. Absorbance values represent the enzyme amount measured using an ELISA kit. The difference between bar pairs marked with *** are significant at p < 0.001

Article Snippet: Queuine hydrochloride (Santa Cruz) was dissolved in dimethyl sulfoxide (DMSO).

Techniques: Activity Assay, Enzyme-linked Immunosorbent Assay