ptx Search Results


non nephrotoxic antibiotic cefotaxime cef  (Gold Biotechnology Inc)
93
Gold Biotechnology Inc non nephrotoxic antibiotic cefotaxime cef
Model of neonatal sepsis-induced AKI. (1) Newborn mice less than 24 hours old were injected intravenously or intraperitoneally with E. coli 105 CFU/g weight or an equal volume of sterile saline for controls. (2) 1.5 hours later, pups were randomly assigned to injection with <t>antibiotic</t> (GENT or <t>CEF),</t> PTX, (antibiotic + PTX) or saline. (3) After additional 4 hours, blood and renal tissue were obtained for (4) bacterial plating and measurements of inflammatory and kidney injury biomarkers. (5) 12 hours after bacterial injections, whole kidneys were harvested and slides were prepared after formalin fixation and paraffin embedding and stained for routine (H&E, PAS) or (6) immunofluorescence microscopy, and then quantitatively analyzed for fluorescence intensity and area of fluorescence.
Non Nephrotoxic Antibiotic Cefotaxime Cef, supplied by Gold Biotechnology Inc, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/non nephrotoxic antibiotic cefotaxime cef/product/Gold Biotechnology Inc
Average 93 stars, based on 1 article reviews
non nephrotoxic antibiotic cefotaxime cef - by Bioz Stars, 2026-03
93/100 stars
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pentoxifylline ptx  (MedChemExpress)
95
MedChemExpress pentoxifylline ptx
Model of neonatal sepsis-induced AKI. (1) Newborn mice less than 24 hours old were injected intravenously or intraperitoneally with E. coli 105 CFU/g weight or an equal volume of sterile saline for controls. (2) 1.5 hours later, pups were randomly assigned to injection with <t>antibiotic</t> (GENT or <t>CEF),</t> PTX, (antibiotic + PTX) or saline. (3) After additional 4 hours, blood and renal tissue were obtained for (4) bacterial plating and measurements of inflammatory and kidney injury biomarkers. (5) 12 hours after bacterial injections, whole kidneys were harvested and slides were prepared after formalin fixation and paraffin embedding and stained for routine (H&E, PAS) or (6) immunofluorescence microscopy, and then quantitatively analyzed for fluorescence intensity and area of fluorescence.
Pentoxifylline Ptx, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/pentoxifylline ptx/product/MedChemExpress
Average 95 stars, based on 1 article reviews
pentoxifylline ptx - by Bioz Stars, 2026-03
95/100 stars
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who 1st international standard for ptx  (European Directorate for the Quality of Medicines and HealthCare)
90
European Directorate for the Quality of Medicines and HealthCare who 1st international standard for ptx
Model of neonatal sepsis-induced AKI. (1) Newborn mice less than 24 hours old were injected intravenously or intraperitoneally with E. coli 105 CFU/g weight or an equal volume of sterile saline for controls. (2) 1.5 hours later, pups were randomly assigned to injection with <t>antibiotic</t> (GENT or <t>CEF),</t> PTX, (antibiotic + PTX) or saline. (3) After additional 4 hours, blood and renal tissue were obtained for (4) bacterial plating and measurements of inflammatory and kidney injury biomarkers. (5) 12 hours after bacterial injections, whole kidneys were harvested and slides were prepared after formalin fixation and paraffin embedding and stained for routine (H&E, PAS) or (6) immunofluorescence microscopy, and then quantitatively analyzed for fluorescence intensity and area of fluorescence.
Who 1st International Standard For Ptx, supplied by European Directorate for the Quality of Medicines and HealthCare, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/who 1st international standard for ptx/product/European Directorate for the Quality of Medicines and HealthCare
Average 90 stars, based on 1 article reviews
who 1st international standard for ptx - by Bioz Stars, 2026-03
90/100 stars
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protx  (Biosynth Carbosynth)
90
Biosynth Carbosynth protx
Model of neonatal sepsis-induced AKI. (1) Newborn mice less than 24 hours old were injected intravenously or intraperitoneally with E. coli 105 CFU/g weight or an equal volume of sterile saline for controls. (2) 1.5 hours later, pups were randomly assigned to injection with <t>antibiotic</t> (GENT or <t>CEF),</t> PTX, (antibiotic + PTX) or saline. (3) After additional 4 hours, blood and renal tissue were obtained for (4) bacterial plating and measurements of inflammatory and kidney injury biomarkers. (5) 12 hours after bacterial injections, whole kidneys were harvested and slides were prepared after formalin fixation and paraffin embedding and stained for routine (H&E, PAS) or (6) immunofluorescence microscopy, and then quantitatively analyzed for fluorescence intensity and area of fluorescence.
Protx, supplied by Biosynth Carbosynth, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/protx/product/Biosynth Carbosynth
Average 90 stars, based on 1 article reviews
protx - by Bioz Stars, 2026-03
90/100 stars
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protx ii  (Biosynth Carbosynth)
90
Biosynth Carbosynth protx ii
Model of neonatal sepsis-induced AKI. (1) Newborn mice less than 24 hours old were injected intravenously or intraperitoneally with E. coli 105 CFU/g weight or an equal volume of sterile saline for controls. (2) 1.5 hours later, pups were randomly assigned to injection with <t>antibiotic</t> (GENT or <t>CEF),</t> PTX, (antibiotic + PTX) or saline. (3) After additional 4 hours, blood and renal tissue were obtained for (4) bacterial plating and measurements of inflammatory and kidney injury biomarkers. (5) 12 hours after bacterial injections, whole kidneys were harvested and slides were prepared after formalin fixation and paraffin embedding and stained for routine (H&E, PAS) or (6) immunofluorescence microscopy, and then quantitatively analyzed for fluorescence intensity and area of fluorescence.
Protx Ii, supplied by Biosynth Carbosynth, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 90 stars, based on 1 article reviews
protx ii - by Bioz Stars, 2026-03
90/100 stars
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psalmotoxin 1 pctx1  (Biosynth Carbosynth)
92
Biosynth Carbosynth psalmotoxin 1 pctx1
Model of neonatal sepsis-induced AKI. (1) Newborn mice less than 24 hours old were injected intravenously or intraperitoneally with E. coli 105 CFU/g weight or an equal volume of sterile saline for controls. (2) 1.5 hours later, pups were randomly assigned to injection with <t>antibiotic</t> (GENT or <t>CEF),</t> PTX, (antibiotic + PTX) or saline. (3) After additional 4 hours, blood and renal tissue were obtained for (4) bacterial plating and measurements of inflammatory and kidney injury biomarkers. (5) 12 hours after bacterial injections, whole kidneys were harvested and slides were prepared after formalin fixation and paraffin embedding and stained for routine (H&E, PAS) or (6) immunofluorescence microscopy, and then quantitatively analyzed for fluorescence intensity and area of fluorescence.
Psalmotoxin 1 Pctx1, supplied by Biosynth Carbosynth, used in various techniques. Bioz Stars score: 92/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/psalmotoxin 1 pctx1/product/Biosynth Carbosynth
Average 92 stars, based on 1 article reviews
psalmotoxin 1 pctx1 - by Bioz Stars, 2026-03
92/100 stars
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anti human crp goat fluorescein conjugated antibody  (Boster Bio)
93
Boster Bio anti human crp goat fluorescein conjugated antibody
Model of neonatal sepsis-induced AKI. (1) Newborn mice less than 24 hours old were injected intravenously or intraperitoneally with E. coli 105 CFU/g weight or an equal volume of sterile saline for controls. (2) 1.5 hours later, pups were randomly assigned to injection with <t>antibiotic</t> (GENT or <t>CEF),</t> PTX, (antibiotic + PTX) or saline. (3) After additional 4 hours, blood and renal tissue were obtained for (4) bacterial plating and measurements of inflammatory and kidney injury biomarkers. (5) 12 hours after bacterial injections, whole kidneys were harvested and slides were prepared after formalin fixation and paraffin embedding and stained for routine (H&E, PAS) or (6) immunofluorescence microscopy, and then quantitatively analyzed for fluorescence intensity and area of fluorescence.
Anti Human Crp Goat Fluorescein Conjugated Antibody, supplied by Boster Bio, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/anti human crp goat fluorescein conjugated antibody/product/Boster Bio
Average 93 stars, based on 1 article reviews
anti human crp goat fluorescein conjugated antibody - by Bioz Stars, 2026-03
93/100 stars
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serum ptx 3 levels  (Shanghai Korain Biotech Co Ltd)
93
Shanghai Korain Biotech Co Ltd serum ptx 3 levels
Model of neonatal sepsis-induced AKI. (1) Newborn mice less than 24 hours old were injected intravenously or intraperitoneally with E. coli 105 CFU/g weight or an equal volume of sterile saline for controls. (2) 1.5 hours later, pups were randomly assigned to injection with <t>antibiotic</t> (GENT or <t>CEF),</t> PTX, (antibiotic + PTX) or saline. (3) After additional 4 hours, blood and renal tissue were obtained for (4) bacterial plating and measurements of inflammatory and kidney injury biomarkers. (5) 12 hours after bacterial injections, whole kidneys were harvested and slides were prepared after formalin fixation and paraffin embedding and stained for routine (H&E, PAS) or (6) immunofluorescence microscopy, and then quantitatively analyzed for fluorescence intensity and area of fluorescence.
Serum Ptx 3 Levels, supplied by Shanghai Korain Biotech Co Ltd, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/serum ptx 3 levels/product/Shanghai Korain Biotech Co Ltd
Average 93 stars, based on 1 article reviews
serum ptx 3 levels - by Bioz Stars, 2026-03
93/100 stars
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paclitaxel ptx  (LC Laboratories)
90
LC Laboratories paclitaxel ptx
Model of neonatal sepsis-induced AKI. (1) Newborn mice less than 24 hours old were injected intravenously or intraperitoneally with E. coli 105 CFU/g weight or an equal volume of sterile saline for controls. (2) 1.5 hours later, pups were randomly assigned to injection with <t>antibiotic</t> (GENT or <t>CEF),</t> PTX, (antibiotic + PTX) or saline. (3) After additional 4 hours, blood and renal tissue were obtained for (4) bacterial plating and measurements of inflammatory and kidney injury biomarkers. (5) 12 hours after bacterial injections, whole kidneys were harvested and slides were prepared after formalin fixation and paraffin embedding and stained for routine (H&E, PAS) or (6) immunofluorescence microscopy, and then quantitatively analyzed for fluorescence intensity and area of fluorescence.
Paclitaxel Ptx, supplied by LC Laboratories, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/paclitaxel ptx/product/LC Laboratories
Average 90 stars, based on 1 article reviews
paclitaxel ptx - by Bioz Stars, 2026-03
90/100 stars
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ptx lot number 1001  (Hooke Laboratories)
90
Hooke Laboratories ptx lot number 1001
Model of neonatal sepsis-induced AKI. (1) Newborn mice less than 24 hours old were injected intravenously or intraperitoneally with E. coli 105 CFU/g weight or an equal volume of sterile saline for controls. (2) 1.5 hours later, pups were randomly assigned to injection with <t>antibiotic</t> (GENT or <t>CEF),</t> PTX, (antibiotic + PTX) or saline. (3) After additional 4 hours, blood and renal tissue were obtained for (4) bacterial plating and measurements of inflammatory and kidney injury biomarkers. (5) 12 hours after bacterial injections, whole kidneys were harvested and slides were prepared after formalin fixation and paraffin embedding and stained for routine (H&E, PAS) or (6) immunofluorescence microscopy, and then quantitatively analyzed for fluorescence intensity and area of fluorescence.
Ptx Lot Number 1001, supplied by Hooke Laboratories, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/ptx lot number 1001/product/Hooke Laboratories
Average 90 stars, based on 1 article reviews
ptx lot number 1001 - by Bioz Stars, 2026-03
90/100 stars
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standard non-ptx circular-polarized (cp) pulses  (Siemens AG)
90
Siemens AG standard non-ptx circular-polarized (cp) pulses
Model of neonatal sepsis-induced AKI. (1) Newborn mice less than 24 hours old were injected intravenously or intraperitoneally with E. coli 105 CFU/g weight or an equal volume of sterile saline for controls. (2) 1.5 hours later, pups were randomly assigned to injection with <t>antibiotic</t> (GENT or <t>CEF),</t> PTX, (antibiotic + PTX) or saline. (3) After additional 4 hours, blood and renal tissue were obtained for (4) bacterial plating and measurements of inflammatory and kidney injury biomarkers. (5) 12 hours after bacterial injections, whole kidneys were harvested and slides were prepared after formalin fixation and paraffin embedding and stained for routine (H&E, PAS) or (6) immunofluorescence microscopy, and then quantitatively analyzed for fluorescence intensity and area of fluorescence.
Standard Non Ptx Circular Polarized (Cp) Pulses, supplied by Siemens AG, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/standard non-ptx circular-polarized (cp) pulses/product/Siemens AG
Average 90 stars, based on 1 article reviews
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90/100 stars
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pertussis toxin ptx  (List Biological Laboratories)
90
List Biological Laboratories pertussis toxin ptx
Model of neonatal sepsis-induced AKI. (1) Newborn mice less than 24 hours old were injected intravenously or intraperitoneally with E. coli 105 CFU/g weight or an equal volume of sterile saline for controls. (2) 1.5 hours later, pups were randomly assigned to injection with <t>antibiotic</t> (GENT or <t>CEF),</t> PTX, (antibiotic + PTX) or saline. (3) After additional 4 hours, blood and renal tissue were obtained for (4) bacterial plating and measurements of inflammatory and kidney injury biomarkers. (5) 12 hours after bacterial injections, whole kidneys were harvested and slides were prepared after formalin fixation and paraffin embedding and stained for routine (H&E, PAS) or (6) immunofluorescence microscopy, and then quantitatively analyzed for fluorescence intensity and area of fluorescence.
Pertussis Toxin Ptx, supplied by List Biological Laboratories, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/pertussis toxin ptx/product/List Biological Laboratories
Average 90 stars, based on 1 article reviews
pertussis toxin ptx - by Bioz Stars, 2026-03
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Image Search Results


Model of neonatal sepsis-induced AKI. (1) Newborn mice less than 24 hours old were injected intravenously or intraperitoneally with E. coli 105 CFU/g weight or an equal volume of sterile saline for controls. (2) 1.5 hours later, pups were randomly assigned to injection with antibiotic (GENT or CEF), PTX, (antibiotic + PTX) or saline. (3) After additional 4 hours, blood and renal tissue were obtained for (4) bacterial plating and measurements of inflammatory and kidney injury biomarkers. (5) 12 hours after bacterial injections, whole kidneys were harvested and slides were prepared after formalin fixation and paraffin embedding and stained for routine (H&E, PAS) or (6) immunofluorescence microscopy, and then quantitatively analyzed for fluorescence intensity and area of fluorescence.

Journal: Frontiers in Cellular and Infection Microbiology

Article Title: Attenuation of acute kidney injury in a murine model of neonatal Escherichia coli sepsis

doi: 10.3389/fcimb.2024.1507914

Figure Lengend Snippet: Model of neonatal sepsis-induced AKI. (1) Newborn mice less than 24 hours old were injected intravenously or intraperitoneally with E. coli 105 CFU/g weight or an equal volume of sterile saline for controls. (2) 1.5 hours later, pups were randomly assigned to injection with antibiotic (GENT or CEF), PTX, (antibiotic + PTX) or saline. (3) After additional 4 hours, blood and renal tissue were obtained for (4) bacterial plating and measurements of inflammatory and kidney injury biomarkers. (5) 12 hours after bacterial injections, whole kidneys were harvested and slides were prepared after formalin fixation and paraffin embedding and stained for routine (H&E, PAS) or (6) immunofluorescence microscopy, and then quantitatively analyzed for fluorescence intensity and area of fluorescence.

Article Snippet: Pups were then treated ip with either gentamicin (GENT) (5 μg per g body weight; Fresenius Kabi; Lake Zurich, IL ) or the non-nephrotoxic antibiotic cefotaxime (CEF) (25 μg per g body weight; GoldBio; St. Louis, MO ), PTX (60 μg per g body weight; VWR International, LLC; Buffalo Grove, IL ), combined antibiotic and PTX, or an equal volume of sterile saline control, starting at 1.5 hours after sepsis initiation.

Techniques: Injection, Sterility, Saline, Staining, Immunofluorescence, Microscopy, Fluorescence

Increased NGAL- and KIM-1 staining of proximal tubules in E. coli -septic newborn mice. Immunofluorescent images of formalin-fixed paraffin-embedded kidney sections from 7 days old healthy controls (A, E, I) , untreated E. coli -septic pups (B, F, J) , as well as E. coli -septic pups treated with CEF (C, G, K) or combined CEF and PTX (D, H, L) 12h after bacterial ip injection ( E. coli 10 5 CFU/g body weight) after anti-NGAL (cat. # ab216462, Abcam; Waltham, MA ) (A-H) or anti-KIM-1 (cat. # AF1817, R&D Systems; Minneapolis, MN ) (I–L) labeling, Alexa Fluor 568-conjugated secondary antibody, Hoechst ( AnaSpec, Inc.; Fremont, CA ), and fluorescein-conjugated Lotus Tetragonolobus lectin ( Vector Laboratories, Inc.; Newark, CA ) staining, at 20x magnification. Panels (A–D) show the red channel only (NGAL), panels (E–H) represent 3-color overlays for NGAL-stained, and panels (I–L) demonstrate 3-channel overlays of KIM-1-stained images (red: NGAL or KIM-1, respectively; green: Lotus Tetragonolobus lectin; blue: DAPI). These representative images demonstrated increased staining for the injury markers NGAL and KIM-1 in septic pups compared to controls (see also <xref ref-type= Figure 11 ), as well as the effects of antibiotic and anti-inflammatory treatment with CEF with/without PTX. " width="100%" height="100%">

Journal: Frontiers in Cellular and Infection Microbiology

Article Title: Attenuation of acute kidney injury in a murine model of neonatal Escherichia coli sepsis

doi: 10.3389/fcimb.2024.1507914

Figure Lengend Snippet: Increased NGAL- and KIM-1 staining of proximal tubules in E. coli -septic newborn mice. Immunofluorescent images of formalin-fixed paraffin-embedded kidney sections from 7 days old healthy controls (A, E, I) , untreated E. coli -septic pups (B, F, J) , as well as E. coli -septic pups treated with CEF (C, G, K) or combined CEF and PTX (D, H, L) 12h after bacterial ip injection ( E. coli 10 5 CFU/g body weight) after anti-NGAL (cat. # ab216462, Abcam; Waltham, MA ) (A-H) or anti-KIM-1 (cat. # AF1817, R&D Systems; Minneapolis, MN ) (I–L) labeling, Alexa Fluor 568-conjugated secondary antibody, Hoechst ( AnaSpec, Inc.; Fremont, CA ), and fluorescein-conjugated Lotus Tetragonolobus lectin ( Vector Laboratories, Inc.; Newark, CA ) staining, at 20x magnification. Panels (A–D) show the red channel only (NGAL), panels (E–H) represent 3-color overlays for NGAL-stained, and panels (I–L) demonstrate 3-channel overlays of KIM-1-stained images (red: NGAL or KIM-1, respectively; green: Lotus Tetragonolobus lectin; blue: DAPI). These representative images demonstrated increased staining for the injury markers NGAL and KIM-1 in septic pups compared to controls (see also Figure 11 ), as well as the effects of antibiotic and anti-inflammatory treatment with CEF with/without PTX.

Article Snippet: Pups were then treated ip with either gentamicin (GENT) (5 μg per g body weight; Fresenius Kabi; Lake Zurich, IL ) or the non-nephrotoxic antibiotic cefotaxime (CEF) (25 μg per g body weight; GoldBio; St. Louis, MO ), PTX (60 μg per g body weight; VWR International, LLC; Buffalo Grove, IL ), combined antibiotic and PTX, or an equal volume of sterile saline control, starting at 1.5 hours after sepsis initiation.

Techniques: Staining, Formalin-fixed Paraffin-Embedded, Injection, Labeling, Plasmid Preparation