ptger2 Search Results


rabbit polyclonal antibodies against ep2  (Alomone Labs)
91
Alomone Labs rabbit polyclonal antibodies against ep2
Rabbit Polyclonal Antibodies Against Ep2, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 91/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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rabbit polyclonal antibodies against ep2 - by Bioz Stars, 2026-06
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mouse igg2b anti ep2 ptger2 r d systems mab6656  (R&D Systems)
90
R&D Systems mouse igg2b anti ep2 ptger2 r d systems mab6656
Mouse Igg2b Anti Ep2 Ptger2 R D Systems Mab6656, supplied by R&D Systems, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 90 stars, based on 1 article reviews
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anti ep4  (Proteintech)
93
Proteintech anti ep4
Anti Ep4, supplied by Proteintech, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 93 stars, based on 1 article reviews
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e2 cat no nbp3 00461  (Novus Biologicals)
90
Novus Biologicals e2 cat no nbp3 00461
E2 Cat No Nbp3 00461, supplied by Novus Biologicals, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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gene exp ptger2 mm00436051 m1  (Thermo Fisher)
99
Thermo Fisher gene exp ptger2 mm00436051 m1
Gene Exp Ptger2 Mm00436051 M1, supplied by Thermo Fisher, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 99 stars, based on 1 article reviews
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gene exp ptger2 rn00579419 m1  (Thermo Fisher)
90
Thermo Fisher gene exp ptger2 rn00579419 m1
Gene Exp Ptger2 Rn00579419 M1, supplied by Thermo Fisher, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 90 stars, based on 1 article reviews
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gene exp ptger2 hs00168754 m1  (Thermo Fisher)
85
Thermo Fisher gene exp ptger2 hs00168754 m1
Validation experiments in SScL and NORML pericytes (A and B) Transcript levels of (A) <t>PTGER2</t> and (B) PTGER3 in SScL pericytes ( n = 5) relative to NORML pericytes ( n = 5). (C) Levels of cAMP were measured in NORML ( n = 3) and SScL ( n = 3) pericytes treated with vehicle (VEH, 500 nM), PGE2 (500 nM), or forskolin (FOR, 100 mM) for 15 min. (D) Protein abundance of pAKT normalized by total AKT in NORML ( n = 3) and SScL ( n = 4) pericytes treated with PGE2 and VEH. ∗ p < 0.05, ∗∗ p < 0.01, ∗∗∗ p < 0.001 as indicated by the lines; @ p < 0.05, @@ p < 0.01, @@@ p < 0.001 versus VEH-NORML (in black) or VEH-SScL (in orange). Data are represented as mean ± SEM.
Gene Exp Ptger2 Hs00168754 M1, supplied by Thermo Fisher, used in various techniques. Bioz Stars score: 85/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 85 stars, based on 1 article reviews
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gene exp ptger2 ec03469468 m1  (Thermo Fisher)
93
Thermo Fisher gene exp ptger2 ec03469468 m1
Validation experiments in SScL and NORML pericytes (A and B) Transcript levels of (A) <t>PTGER2</t> and (B) PTGER3 in SScL pericytes ( n = 5) relative to NORML pericytes ( n = 5). (C) Levels of cAMP were measured in NORML ( n = 3) and SScL ( n = 3) pericytes treated with vehicle (VEH, 500 nM), PGE2 (500 nM), or forskolin (FOR, 100 mM) for 15 min. (D) Protein abundance of pAKT normalized by total AKT in NORML ( n = 3) and SScL ( n = 4) pericytes treated with PGE2 and VEH. ∗ p < 0.05, ∗∗ p < 0.01, ∗∗∗ p < 0.001 as indicated by the lines; @ p < 0.05, @@ p < 0.01, @@@ p < 0.001 versus VEH-NORML (in black) or VEH-SScL (in orange). Data are represented as mean ± SEM.
Gene Exp Ptger2 Ec03469468 M1, supplied by Thermo Fisher, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 93 stars, based on 1 article reviews
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mouse monoclonal antibody against ep4  (Proteintech)
93
Proteintech mouse monoclonal antibody against ep4
Validation experiments in SScL and NORML pericytes (A and B) Transcript levels of (A) <t>PTGER2</t> and (B) PTGER3 in SScL pericytes ( n = 5) relative to NORML pericytes ( n = 5). (C) Levels of cAMP were measured in NORML ( n = 3) and SScL ( n = 3) pericytes treated with vehicle (VEH, 500 nM), PGE2 (500 nM), or forskolin (FOR, 100 mM) for 15 min. (D) Protein abundance of pAKT normalized by total AKT in NORML ( n = 3) and SScL ( n = 4) pericytes treated with PGE2 and VEH. ∗ p < 0.05, ∗∗ p < 0.01, ∗∗∗ p < 0.001 as indicated by the lines; @ p < 0.05, @@ p < 0.01, @@@ p < 0.001 versus VEH-NORML (in black) or VEH-SScL (in orange). Data are represented as mean ± SEM.
Mouse Monoclonal Antibody Against Ep4, supplied by Proteintech, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/mouse monoclonal antibody against ep4/product/Proteintech
Average 93 stars, based on 1 article reviews
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gene exp ptger2 hs04183523 m1  (Thermo Fisher)
86
Thermo Fisher gene exp ptger2 hs04183523 m1
Validation experiments in SScL and NORML pericytes (A and B) Transcript levels of (A) <t>PTGER2</t> and (B) PTGER3 in SScL pericytes ( n = 5) relative to NORML pericytes ( n = 5). (C) Levels of cAMP were measured in NORML ( n = 3) and SScL ( n = 3) pericytes treated with vehicle (VEH, 500 nM), PGE2 (500 nM), or forskolin (FOR, 100 mM) for 15 min. (D) Protein abundance of pAKT normalized by total AKT in NORML ( n = 3) and SScL ( n = 4) pericytes treated with PGE2 and VEH. ∗ p < 0.05, ∗∗ p < 0.01, ∗∗∗ p < 0.001 as indicated by the lines; @ p < 0.05, @@ p < 0.01, @@@ p < 0.001 versus VEH-NORML (in black) or VEH-SScL (in orange). Data are represented as mean ± SEM.
Gene Exp Ptger2 Hs04183523 M1, supplied by Thermo Fisher, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 86 stars, based on 1 article reviews
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prostaglandin 2  (Cusabio)
93
Cusabio prostaglandin 2
Validation experiments in SScL and NORML pericytes (A and B) Transcript levels of (A) <t>PTGER2</t> and (B) PTGER3 in SScL pericytes ( n = 5) relative to NORML pericytes ( n = 5). (C) Levels of cAMP were measured in NORML ( n = 3) and SScL ( n = 3) pericytes treated with vehicle (VEH, 500 nM), PGE2 (500 nM), or forskolin (FOR, 100 mM) for 15 min. (D) Protein abundance of pAKT normalized by total AKT in NORML ( n = 3) and SScL ( n = 4) pericytes treated with PGE2 and VEH. ∗ p < 0.05, ∗∗ p < 0.01, ∗∗∗ p < 0.001 as indicated by the lines; @ p < 0.05, @@ p < 0.01, @@@ p < 0.001 versus VEH-NORML (in black) or VEH-SScL (in orange). Data are represented as mean ± SEM.
Prostaglandin 2, supplied by Cusabio, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 93 stars, based on 1 article reviews
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ep2  (OriGene)
92
OriGene ep2
Validation experiments in SScL and NORML pericytes (A and B) Transcript levels of (A) <t>PTGER2</t> and (B) PTGER3 in SScL pericytes ( n = 5) relative to NORML pericytes ( n = 5). (C) Levels of cAMP were measured in NORML ( n = 3) and SScL ( n = 3) pericytes treated with vehicle (VEH, 500 nM), PGE2 (500 nM), or forskolin (FOR, 100 mM) for 15 min. (D) Protein abundance of pAKT normalized by total AKT in NORML ( n = 3) and SScL ( n = 4) pericytes treated with PGE2 and VEH. ∗ p < 0.05, ∗∗ p < 0.01, ∗∗∗ p < 0.001 as indicated by the lines; @ p < 0.05, @@ p < 0.01, @@@ p < 0.001 versus VEH-NORML (in black) or VEH-SScL (in orange). Data are represented as mean ± SEM.
Ep2, supplied by OriGene, used in various techniques. Bioz Stars score: 92/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 92 stars, based on 1 article reviews
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Image Search Results


Validation experiments in SScL and NORML pericytes (A and B) Transcript levels of (A) PTGER2 and (B) PTGER3 in SScL pericytes ( n = 5) relative to NORML pericytes ( n = 5). (C) Levels of cAMP were measured in NORML ( n = 3) and SScL ( n = 3) pericytes treated with vehicle (VEH, 500 nM), PGE2 (500 nM), or forskolin (FOR, 100 mM) for 15 min. (D) Protein abundance of pAKT normalized by total AKT in NORML ( n = 3) and SScL ( n = 4) pericytes treated with PGE2 and VEH. ∗ p < 0.05, ∗∗ p < 0.01, ∗∗∗ p < 0.001 as indicated by the lines; @ p < 0.05, @@ p < 0.01, @@@ p < 0.001 versus VEH-NORML (in black) or VEH-SScL (in orange). Data are represented as mean ± SEM.

Journal: iScience

Article Title: Transcriptomic characterization of lung pericytes in systemic sclerosis-associated pulmonary fibrosis

doi: 10.1016/j.isci.2024.110010

Figure Lengend Snippet: Validation experiments in SScL and NORML pericytes (A and B) Transcript levels of (A) PTGER2 and (B) PTGER3 in SScL pericytes ( n = 5) relative to NORML pericytes ( n = 5). (C) Levels of cAMP were measured in NORML ( n = 3) and SScL ( n = 3) pericytes treated with vehicle (VEH, 500 nM), PGE2 (500 nM), or forskolin (FOR, 100 mM) for 15 min. (D) Protein abundance of pAKT normalized by total AKT in NORML ( n = 3) and SScL ( n = 4) pericytes treated with PGE2 and VEH. ∗ p < 0.05, ∗∗ p < 0.01, ∗∗∗ p < 0.001 as indicated by the lines; @ p < 0.05, @@ p < 0.01, @@@ p < 0.001 versus VEH-NORML (in black) or VEH-SScL (in orange). Data are represented as mean ± SEM.

Article Snippet: PTGER2 , Applied Biosystems , Hs00168754_m1.

Techniques: Biomarker Discovery, Quantitative Proteomics

Role of PTGER2 and PTGER3 in lung inflammation and fibrosis (A) Under normal conditions, activation of PTGER2 (aka EP2) by PGE2 initiates activation of cAMP and PKA cascades that inhibit calcium waves and the PI3K/AKT signaling pathway, thus conferring protection against pulmonary inflammation and fibrosis. , , (B) In contrast, PGE2 signaling through PTGER3 (aka EP3) inhibits cAMP production and increases intracellular Ca 2+ concentration. , (C) The transcriptomic signature we observed in our RNA-seq analysis revealed that PTGER2 is downregulated and PTGER3 is upregulated in SScL pericytes, a signature that has been shown to lead to the loss of protection against lung inflammation and fibrosis.

Journal: iScience

Article Title: Transcriptomic characterization of lung pericytes in systemic sclerosis-associated pulmonary fibrosis

doi: 10.1016/j.isci.2024.110010

Figure Lengend Snippet: Role of PTGER2 and PTGER3 in lung inflammation and fibrosis (A) Under normal conditions, activation of PTGER2 (aka EP2) by PGE2 initiates activation of cAMP and PKA cascades that inhibit calcium waves and the PI3K/AKT signaling pathway, thus conferring protection against pulmonary inflammation and fibrosis. , , (B) In contrast, PGE2 signaling through PTGER3 (aka EP3) inhibits cAMP production and increases intracellular Ca 2+ concentration. , (C) The transcriptomic signature we observed in our RNA-seq analysis revealed that PTGER2 is downregulated and PTGER3 is upregulated in SScL pericytes, a signature that has been shown to lead to the loss of protection against lung inflammation and fibrosis.

Article Snippet: PTGER2 , Applied Biosystems , Hs00168754_m1.

Techniques: Activation Assay, Concentration Assay, RNA Sequencing

Journal: iScience

Article Title: Transcriptomic characterization of lung pericytes in systemic sclerosis-associated pulmonary fibrosis

doi: 10.1016/j.isci.2024.110010

Figure Lengend Snippet:

Article Snippet: PTGER2 , Applied Biosystems , Hs00168754_m1.

Techniques: Recombinant, cAMP Assay, Reverse Transcription, Western Blot, Software